Agonist-bound nuclear receptors: Not just targets of coactivators

Journal of Molecular Endocrinology

Volumn 31, Issue 1, 2003, Pages 1-7

  Fernandes, I ^a   White, John H ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; CELL NUCLEUS RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; HORMONE RECEPTOR STIMULATING AGENT; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P160; RETINOIC ACID RECEPTOR; RETINOL DERIVATIVE; STEROID RECEPTOR; THIAZOLIDINE DERIVATIVE; THYROID HORMONE RECEPTOR; TRANSCRIPTION FACTOR; TRICHOSTATIN A; VITAMIN D DERIVATIVE; XENOBIOTIC AGENT;

AGONIST; ATTENUATION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC ANALYSIS; HUMAN; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; CYTOSKELETAL PROTEINS; HISTONE DEACETYLASES; HUMANS; MODELS, BIOLOGICAL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 0042854938     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0310001     Document Type: Review

References (37)

1. Becker M, Baumann C, John S, Walker DA, Vigneron M, McNally JG & Hager GL 2002 Dynamic behavior of transcription factors on a natural promoter in living cells. EMBO Reports 3 1188-1194.
2. Burakov D, Crofts LA, Chang CPB & Freedman LP 2002 Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor. Journal of Biological Chemistry 277 14359-14362.
3. Cavaillès V, Dauvois S, L'Horset F, Lopez G, Hoare S, Kushner PJ & Parker MG 1995 Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO Journal 14 3741-3751.
4. Chawla A, Repa J, Evans RM & Mangelsdorf DJ 2001 Nuclear receptors and lipid physiology: opening the X-files. Science 294 1866-1870.
5. Chen JD & Evans RM 1995 A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377 454-457.
6. Chinnadurai G 2002 CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Molecular Cell 9 213-224.
7. Eng FCS, Barsalou A, Akutsu N, Mercier I, Zechel C, Mader S & White JH 1998 Different classes of coactivators recognize distinct but overlapping sites on the estrogen receptor ligand binding domain. Journal of Biological Chemistry 273 28371-28377.
8. Fernandes I, Bastien Y, Wai T, Nygard K, Lin R, Cormier O, Lee HS, Eng F, Bertos NR, Pelletier N et al. 2003 Ligand-dependent corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms. Molecular Cell 11 139-150.
9. Font de Mora J & Brown M 2000 AIB1 is a signaling conduit for kinase-mediated growth factor signaling to the estrogen receptor. Molecular and Cellular Biology 20 5041-5047.
10. Glass CK & Rosenfeld MG 2000 The coregulator exchange in transcriptional functions of nuclear receptors. Genes and Development 14 121-141.
11. Heery DM, Kalkhoven E, Hoare S & Parker MG 1997 A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387 733-736.
12. Horlein AJ, Naar AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, Ryan A, Kamei Y, Soderstrom M, Glass CK & Rosenfeld MG 1995 Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377 397-404.
13. Huang NW, vom Baur E, Garnier JM, Lerouge T, Vonesch JL, Lutz Y, Chambon P & Losson R 1998 Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO Journal 17 3398-3412.
14. Inoue A, Yoshida N, Omoto Y, Oguchi S, Yamori T, Kiyama R & Hayashi S 200 Development of cDNA microarray for expression profiling of estrogen-responsive genes. Journal of Molecular Endocrinology 29 175-192.
15. Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchyama S, Sasaki H, Masushige S, Gotoh Y, Hishida E, Kawashima H, Metzger D & Chambon P 1995 Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270 1491-1494.
16. Le Douarin B, Zechel C, Garnier JM, Lutz Y, Tora L, Pierrat P, Heery D, Gronemeyer H, Chambon P & Losson R 1995 The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO Journal 14 2020-2033.
17. Lee CH, Chinpaisal C & Wei LN 1998 Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2. Molecular and Cellular Biology 18 6745-6755.
18. Lin R, Nagai Y, Sladek R, Bastien Y, Ho J, Petrecca K, Sotiropoulou G, Diamandis EP, Hudson T & White JH 2002 Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 signaling on cell proliferation, differentiation and immune system regulation. Molecular Endocrinology 16 1243-1256.
19. Lobenhofer EK, Bennett L, Cable PL, Li LP, Bushel PR & Afshari CA 2002 Regulation of DNA replication fork genes by 17 beta-estradiol. Molecular Endocrinology 16 1215-1229.
20. McKenna NJ & O'Malley BW 2002 Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108 465-474.
21. McNally JG, Muller WG, Walker D, Wolford R & Hager GL 2000 The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science 287 1262-1265.
22. Miyata KS, McCaw SE, Meertens LM, Patel HV, Rachubinski RA & Capone JP 1998 Receptor-interacting protein 140 interacts with and inhibits transactivation by peroxisome proliferator-activated receptor alpha and liver-X-receptor alpha. Molecular and Cellular Endocrinology 146 69-76.
23. Ng HH & Bird A 2001 Histone deacetylases: silencers for hire. Trends in Biochemical Science 25 121-126.
24. Nielsen AL, Ortiz JA, You J, Oulad-Abdelghani M, Khechumian R, Gansmuller A, Chambon P & Losson R 1999 Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. EMBO Journal 18 6385-6395.
25. Perissi V, Staszewski LM, McInerney EM, Kurokawa R, Krones A, Rose DW, Lambert MH, Milburn MV, Glass CK & Rosenfeld MG 1999 Molecular determinants of nuclear receptor-corepressor interaction. Genes and Development 13 3198-3208.
26. Rajendran RR, Nye AC, Frasor J, Balsara RD, Martini PGV & Katzenellenbogen BS 2003 Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97). Journal of Biological Chemistry 278 4628-4638.
27. Renaud JP & Moras D 2000 Structural studies on nuclear receptors. Cell and Molecular Life Science 57 1748-1769.
28. Rosenfeld MG & Glass CK 2001 Coregulator codes of transcriptional regulation by nuclear receptors. Journal of Biological Chemistry 276 36865-36868.
29. Sanchez R, Nguyen D, Rocha W, White JH & Mader S 2002 Diversity in the mechanisms of gene regulation by estrogen receptors. BioEssays 24 244-254.
30. Shang Y, Xiao H, DiRenzo J, Lazar MA & Brown M 2000 Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103 843-852.
31. Shao D & Lazar M 1999 Modulating nuclear receptor function: may the phos be with you. Journal of Clinical Investigation 103 1617-1618.
32. Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS & Mancini MA 2001 Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor α-coactivator complexes in living cells. Molecular and Cellular Biology 21 4404-4412.
33. Treuter E, Albrektsen T, Johansson L, Leers J & Gustafsson JA 1998 A regulatory role for RIP140 in nuclear receptor activation. Molecular Endocrinology 12 864-881.
34. Vo N, Fjeld C & Goodman RH 2001 Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates its interaction with CtBP. Molecular and Cellular Biology 21 6181-6188.
35. Voegel JJ, Heine MJS, Zechel C & Chambon P 1996 The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways. EMBO Journal 13 3667-3675.
36. Wan YH & Nordeen SK 2002 Overlapping but distinct gene regulation profiles by glucocorticoids and progestins in human breast cancer cell. Molecular Endocrinology 16 1204-1214.
37. Wei LN, Hu XL, Chandra D, Seto E & Farooqui M 2000 Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing. Journal of Biological Chemistry 275 40782-40787.