Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: A novel component involved in cisplatin- and doxorubicin-provoked cell kill

Molecular Pharmacology

Volumn 64, Issue 2, 2003, Pages 259-268

  Schenk, Paul W ^a   Brok, Mariël ^a   Boersma, Antonius W M ^a   Brandsma, Jourica A ^b   Den Dulk, Hans ^b   Burger, Herman ^a   Stoter, Gerrit ^a   Brouwer, Jaap ^b   Nooter, Kees ^a,c  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMETABOLITE; CADMIUM CHLORIDE; CISPLATIN; COPPER SULFATE; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; DOXORUBIN; ETOPOSIDE; FLUOROURACIL; METHYLNITRONITROSOGUANIDINE; NITROGEN PERMEASE REGULATOR 2 PROTEIN; OXALIPLATIN; PLATINUM DERIVATIVE; PROTEIN KINASE; REGULATOR PROTEIN; SR PROTEIN SPECIFIC KINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL KILLING; CELLULAR DISTRIBUTION; CLONOGENIC ASSAY; CONTROLLED STUDY; CROSS RESISTANCE; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG RESISTANCE; EPISTASIS; GENE DISRUPTION; GENE THERAPY; HYPERSENSITIVITY; HYPOTHESIS; KNOCKOUT GENE; NONHUMAN; NPR2 GENE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; REGULATOR GENE; SACCHAROMYCES CEREVISIAE; SKY1 GENE; SPONTANEOUS MUTATION; STRAIN IDENTIFICATION; SURVIVAL;

ANTINEOPLASTIC AGENTS; CISPLATIN; DOXORUBICIN; DRUG RESISTANCE; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; PHENOTYPE; PLATINUM; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0042844651     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.2.259     Document Type: Article

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