Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes

Current Biology

Volumn 9, Issue 1, 1999, Pages 51-54

  Durant, Stephen T ^a   Morris, Melanie M ^a   Illand, Maureen ^a   McKay, Helen J ^a   McCormick, Carol ^a   Hirst, Gillian L ^a   Borts, Rhona H ^a,b   Brown, Robert ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SACCHAROMYCES CEREVISIAE;

EID: 0032933747     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(99)80047-5     Document Type: Article

References (24)

1. Modrich P: Strand-specific mismatch repair in mammalian cells. J Biol Chem 1997, 272:24727-24730.
2. Fink D, Aebi S, Howell SB: The role of DNA mismatch repair in drug resistance. Clin Cancer Res 1998, 4:1-6.
3. Karran P, Hampson R: Genomic instability and tolerance to alkylating agents. Cancer Surveys 1996, 28:69-85.
4. Brown R, Hirst GL, Gallagher WM, Mcllwraith AJ, Margison GP, Van der Zee AG, Anthoney DA: hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents. Oncogene 1997, 15:45-52.
5. Kolodner R: Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 1996, 10:1433-1442.
6. Alani E, Reenan RA, Kolodner RD: Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics 1994, 137:19-39.
7. Prolla TA, Christie D, Liskay RM: Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutl gene. Mol Cell Biol 1994, 14:407-415.
8. Lea DE, Coulson CA: The distribution of numbers of mutants in bacterial populations. J Genet 1949, 49:264-285.
9. Petes TD, Malone RE, Syminton LS: Recombination in yeast. In The Molecular and Cellular Biology of The Yeast Saccharomyces. Edited by Broach JR, Pringle JR, Jones EW. Cold Spring Harbour Laboratory Press; 1991:407-521.
10. Zou H, Rothstein R: Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism. Cell 1997, 90:87-96.
11. Fishman-Lobell J, Haber JE: Removal of non-homologous DNA ends in double-strand break recombination: The role of the yeast ultraviolet repair gene RAD1. Science 1992, 258:480-484.
12. Davies AA, Friedberg EC, Tomkinson AE, Wood RD, West SC: Role of Rad1 and Rad10 proteins in nucleotide excision repair and recombination. J Biol Chem 1995, 270:24638-24641.
13. Sugawara N, Paques F, Colaiacovo M, Haber JE: Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. Proc Natl Acad Sci USA 1997, 94:9214-9219.
14. Zamble DB, Lippard SJ: Cisplatin and DNA repair in cancer chemotherapy. Trends Biochem Sci 1995, 20:435-439.
15. Moggs JG, Szymkowski DE, Yamada M, Karran P, Wood RD: Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts. Nucleic Acids Res 1997, 25:480-490.
16. McA'Nulty MM, Lippard SJ: The HMG-domain protein lxr1 blocks excision repair of cisplatin-DNA adducts in yeast. Mutat Res 1996, 362:75-86.
17. Yamada M, O'Regan E, Brown R, Karran P: Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins. Nucleic Acids Res 1997, 25:491-495.
18. Vaisman A, Varchenko M, Umar A, Kunkel TA, Risinger JI, Barrett JC, Hamilton TC, Chaney SG: The role of hmlh1, hmsh3, and hmsh6 defects in cisplatin and oxaliplatin resistance: Correlation with replicative bypass of platinum-DNA adducts. Cancer Res 1998, 58:3579-3585.
19. Bailis AM, Rothstein R: A defect in mismatch repair in Saccharomyces cerevisiae stimulates ectopic recombination between homologous genes by an excision repair dependent process. Genetics 1990, 126:535-547.
20. Datta A, Hendrix M, Lipsstich M, Jinks-Roberston S: Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast Proc Natl Acad Sci USA 1997, 94:9757-9762.
21. Bawa S, Xiao W: A mutation in the MSH5 gene results in alkylation tolerance. Cancer Res 1997, 57:2715-2720.
22. Hunter N, Borts RH: Mlh1p is unique among mismatch repair proteins in its ability to promote crossing over during meiosis. Genes Dev 1997, 11:1573-1582.
23. Schild D, Konforti B, Perez C, Gish W, Mortimer R: Isolation and characterisation of yeast DNA repair genes: I. Cloning of the RAD52 gene. Curr Genet 1983, 7:85-92.
24. Zehfus BR, McWilliams AD, Lin YH, Hoekstra MF, Keil RL: Genetic control of RNA polymerase I-stimulated recombination in yeast. Genetics 1990, 126:41-52.