Role of determinants of cadmium sensitivity in the tolerance of Schizosaccharomyces pombe to cisplatin

Molecular Pharmacology

Volumn 51, Issue 1, 1997, Pages 12-18

  Perego, Paola ^a,c   Weghe, Jennifer Vande ^b   Ow, David W ^b   Howell, Stephen B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; CADMIUM; CISPLATIN; DNA; GLUTATHIONE; RNA; SULFIDE;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG RESISTANCE; DRUG TOLERANCE; GENE MUTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE;

EID: 0031026412     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.51.1.12     Document Type: Article

References (32)

1. Kondo, Y., S.-M. Kuo, S. C. Watkins, and J. S. Lazo. Metallothionein localization and cisplatin resistance in human hormone-independent prostatic tumor cell lines. Cancer Res. 55:474-477 (1995).
2. Andrews, P. A., M. P. Murphy, and S. B. Howell. Differential potentiation of alkylating and platinating agent cytotoxicity in human ovarian carcinoma cells by glutathione depletion. Cancer Res. 45:6250-6253 (1985).
3. Andrews, P. A., N. P. Murphy, and S. B. Howell. Differential sensitization of human ovarian carcinoma and mouse L1210 cells to cisplatin and melphalan by glutathione depletion. Mol. Pharmacol. 30:643-650 (1986).
4. Godwin, A. K., A. Meister, P. J. O'Dwyer, C. S. Huang, T. C. Hamilton, and M. E. Anderson. High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc. Natl. Acad. Sci. USA 89:3070-3074 (1992).
5. Mehra, R. K., and D. R. Winge. Metal ion resistance in fungi: molecular mechanisms and their regulated expression. J. Cell Biol. 45:30-40 (1991).
6. Jeyaprakash, A., J. W. Welch, and S. Fogel. Multicopy CUP1 plasmids enhance cadmium and copper resistance levels in yeast. Mol. Gen. Genet. 225:363-368 (1991).
7. Yu, W., V. Santhanagopalan, A. K. Sewell, L. T. Jensen, and D. R. Winge. Dominance of metallothionein in metal ion buffering in yeast capable of synthesis of (yEC)nG isopeptides. J. Biol. Chem. 269:21010-21015 (1994).
8. Grill, E., E.-L. Winnacker, and M. H. Zenk. Phytochelatins, a class of heavy-metal-binding peptides from plants, are functionally analogous to metallothioneins. Proc. Natl. Acad. Sci. USA 84:439-443 (1987).
9. Robinson, N. J., A. M. Tommey, C. Kuske, and P. J. Jackson. Plant metallothioneins. Biochemistry 295:1-10 (1993).
10. Rauser, W. Phytochelatins and related peptides. Plant Physiol. 109:1141-1149 (1995).
11. Dameron, C. T., R. N. Reese, R. K. Mehra, A. R. Kortan, P. J. Carrol, M. L. Steigerwald, L. E. Brus, and D. R. Winge. Biosynthesis of cadmium sulfide quantum semiconductor crystallites. Nature (Lond.) 338:596-597 (1989).
12. Ortiz, D. F., L. Kreppel, D. M. Speiser, G. Scheel, G. McDonald, and D. W. Ow. Heavy metal tolerance in the fission yeast requires an ATP-binding cassette-type vacuolar membrane transporter. EMBO J. 11:3491-3499 (1992).
13. Prentice, H. L. High-efficiency transformation of Schizosaccharomyces pombe by electroporation. Nucleic Acids Res. 20:621-624 (1992).
14. Speiser, D. M., D. F. Ortiz, L. Kreppel, G. Scheel, G. McDonald, and D. W. Ow. Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe. Mol. Cell. Biol. 12:5301-5310 (1992).
15. Mehra, R. K., P. Mulchandani, and T. C. Hunter. Role of CdS quantum crystallites in cadmium resistance in Candida glabrata. Biochem. Biophys. Res. Commun. 200:1193-1200 (1994).
16. Miquel, J. CRC Handbook of Free Radicals and Antioxidants in Biomedicine. CRC Press, Boca Raton (1993).
17. Perego, P., G. Jimenez, and S. B. Howell. Isolation and characterization of a cisplatin-resistant strain of Schizosaccharomyces pombe. Mol. Pharmacol. 50:1080-1086 (1996).
18. Collart, M. A., and S. Oliviero. Anonymous Current Protocols in Molecular Biology. (1994).
19. Hickey, E., S. E. Branden, S. Sadis, B. Smale, and L. E. Weber. Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia. Gene 43:147-156 (1986).
20. Mutoh, N., and Y. Hayashi. Isolation of mutants of mutants of Schizosaccharomyces pombe unable to synthesize cadystin, small cadmium-binding peptides. Biochem. Biophys. Res. Commun. 151:32-39 (1986).
21. Coblenz, A., and K. Wolf. The role of glutathione biosynthesis in heavy metal resistance in the fission yeast Schizosaccharomyces pombe. FEMS Microbiol. Rev. 14:303-308 (1994)
22. Ortiz, D. F., T. Ruscitti, K. F. McCue, and D. W. Ow. Transport of metal-binding peptides by HMT1, a fission yeast ABC-type vacuolar membrane protein. J. Biol. Chem. 270:4721-4728 (1995).
23. Brzywczy, J., and A. Paszewski. Sulfur amino acid metabolism in Schizosaccharomyces pombe: occurrence of two O-acetylhomoserine sulfhydrylases and the lack of the reverse transsulfuration pathway. FEMS Microbiol. Lett. 121:171-174 (1994).
24. Juang, R. H., K. F. McCue, and D. W. Ow. Two purine biosynthetic enzymes that are required for cadmium tolerance in Schizosaccharomyces pombe utilize cysteine sulfinate in vitro. Arch. Biochem. Biophys. 304:392-401 (1993).
25. Naredi, P., D. D. Heath, R. E. Enns, and S. B. Howell. Cross-resistance between cisplatin, antimony potassium tartrate, and arsenite in human tumor cells. J. Clin. Invest. 95:1193-1198 (1995).
26. Ozols, R. F., P. J. O'Dwyer, T. C. Hamilton, and R. C. Young. The role of glutathione in drug resistance. Cancer Treat. Rev. 17:45-50 (1990).
27. O'Dwyer, P. J., T. C. Hamilton, R. C. Young, F. P. LaCreta, N. Carp, K. Padavic, R. L. Comis, and R. F. Ozols. Depletion of glutathione in normal and malignant human cells in vivo by buthionine sulfoximine: clinical and biochemical results. J. Natl. Cancer Inst. 84:264-267 (1992).
28. O'Dwyer, P. J., T. C. Hamilton, K. S. Yao, K. D. Tew, and R. F. Ozols. Modulation of glutathione and related enzymes in reversal of resistance to anticancer drugs. Hematol. Oncol. Clin. North Am. 9:383-396 (1995).
29. Grill, E., S. Loeffler, E.-L. Winnacker, and M. H. Zenk. Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase). Proc. Natl. Acad. Sci. USA 86:6838-6842 (1989).
30. nG in the cell-free system of the fission yeast. Biochem. Cell Biol. 69:115-121 (1991).
31. Steffens, J. C., D. F. Hunt, and B. G. Williams. Accumulation of non-protein metal binding polypeptides (γ-glutamyl-cysteinyl)n-glycine in selected cadmium-resistant tomato cells. J. Biol. Chem. 261:13879-13882 (1986).
32. Howden, R., P. B. Goldsbrough, C. R. Anderson, and C. S. Cobbett. Cadmium sensitive, cad1 mutants of Arabidopsis thaliana are phytochelatin deficient. Plant Physiol. 107:1059-1066 (1995).