Inhibition of cell proliferation and induction of apoptosis by novel tetravalent peptides inhibiting DNA binding of E2F

Oncogene

Volumn 22, Issue 32, 2003, Pages 4943-4952

  Montigiani, Silvia ^a,b   Müller, Rolf ^a   Kontermann, Roland E ^a,c  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b CHIRON VACCINES   (Italy)

^c Vectron Therapeutics AG   (Germany)

Author keywords

Apoptosis; Cell cycle; E2F; Inhibitor of DNA binding; Peptidomimetics; Phage display; Tat

Indexed keywords

DNA; GLYCYLSERYLARGINYLISOLEUCYLTHREONYLPHENYLALANYLARGINYLSERYLGLYCYLSERYLTRYPT OPHYLTYROSYLALANYLSERINAMIDE; ISOLEUCYLTRYPTOPHYLLEUCYLSERYLGLYCYLLEUCYLSERYLARGINYLGLYCYLVALYLTRYPTOPHYL VALYLSERYLPHENYLALANYLPROLINAMIDE; PEPTIDE D6 10; PEPTIDE D6 11; PEPTIDE D6 8; PEPTIDE S15 3; PEPTIDE S15 7; PHENYLALANYLTRYPTOPHYLLEUCYLARGINYLPHENYLALANYLTHREONINAMIDE; PROTEIN SUBUNIT; SYNTHETIC PEPTIDE; TETRAVALENT PEPTIDE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F2; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR E2F4; TRANSCRIPTION FACTOR E2F5; TRYPTOPHYLHISTIDYLPHENYLALANYLISOLEUCYLPHENYLALANYLTRYPTOPHANAMIDE; TRYPTOPHYLVALYLARGINYLTRYPTOPHYLHISTIDYLPHENYLALANINAMIDE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; E2F1 PROTEIN, HUMAN; E2F2 PROTEIN, HUMAN; E2F4 PROTEIN, HUMAN; PEPTIDE; PEPTIDE LIBRARY; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; HUMAN; HUMAN CELL; INHIBITION KINETICS; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PEPTIDE ANALYSIS; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ISOLATION; PROTEIN STRUCTURE; PROTEIN TARGETING; TRANSCRIPTION REGULATION; VALIDATION PROCESS; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HELA CELL; METABOLISM;

APOPTOSIS; CELL CYCLE PROTEINS; CELL DIVISION; DNA; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; E2F2 TRANSCRIPTION FACTOR; E2F3 TRANSCRIPTION FACTOR; E2F4 TRANSCRIPTION FACTOR; E2F5 TRANSCRIPTION FACTOR; HELA CELLS; HUMANS; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 0042786010     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206495     Document Type: Article

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