Effects of the CGRP receptor antagonist BIBN4096BS on capsaicin-induced carotid haemodynamic changes in anaesthetised pigs

British Journal of Pharmacology

Volumn 140, Issue 2, 2003, Pages 329-338

  Kapoor, Kapil ^a   Arulmani, Udayasankar ^a   Heiligers, Jan P C ^a   Garrelds, Ingrid M ^a   Willems, Edwin W ^a   Doods, Henri ^b   Villalón, Carlos M ^c   Saxena, Pramod R ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Arteriovenous anastomoses; BIBN4096BS; Capsaicin; Carotid circulation; CGRP; CGRP receptor antagonists; Microspheres; Migraine and pig

Indexed keywords

ANTIMIGRAINE AGENT; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; N [2 [[5 AMINO 1 [[4 (4 PYRIDINYL) 1 PIPERAZINYL]CARBONYL]PENTYL]AMINO] 1 [(3,5 DIBROMO 4 HYDROXYPHENYL)METHYL] 2 OXOETHYL] 4 (1,4 DIHYDRO 2 OXO 3(2H) QUINAZOLINYL) 1 PIPERIDINECARBOXAMIDE; OLCEGEPANT; UNCLASSIFIED DRUG;

ANESTHESIA; ARTERIAL OXYGEN SATURATION; ARTERIOVENOUS FISTULA; ARTICLE; CAROTID ARTERY FLOW; CAROTID ARTERY PULSE; CONDUCTANCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; HEART RATE; HEMODYNAMICS; JUGULAR VEIN; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SWINE; TISSUE BLOOD FLOW; VENOUS OXYGEN TENSION;

ANESTHESIA; ANIMALS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CALCITONIN GENE-RELATED PEPTIDE; CAPSAICIN; CAROTID ARTERIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART RATE; HEMODYNAMIC PROCESSES; JUGULAR VEINS; OXYGEN; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; SWINE;

EID: 0042634735     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705451     Document Type: Article

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