Neuronal messengers in the human cerebral circulation

Peptides

Volumn 22, Issue 6, 2001, Pages 995-1007

  Gulbenkian, Sérgio ^a   Uddman, Rolf ^b   Edvinsson, Lars ^b  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CALCITONIN GENE RELATED PEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; NEUROKININ; NEUROPEPTIDE; NEUROPEPTIDE Y; NEUROTRANSMITTER; NITRIC OXIDE; NORADRENALIN; SEROTONIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ADRENERGIC SYSTEM; ARTICLE; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; CHOLINERGIC SYSTEM; DENERVATION; IMMUNOHISTOCHEMISTRY; NERVE FIBER; NEUROTRANSMISSION; PARASYMPATHETIC GANGLION; PARASYMPATHETIC NERVE; PRIORITY JOURNAL; SENSORY NERVE; SUPERIOR CERVICAL GANGLION; TRIGEMINUS GANGLION;

EID: 0035009860     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00408-9     Document Type: Review

References (146)

1. Noradrenergic innervation of gerbil large cerebral arteries
2. Presence of the predicted C-flanking peptide of neuropeptide Y (C-PON) in tissue extracts
3. Vasorelaxant effect of PACAP-27 on canine cerebral arteries and rat intracerebral arterioles
4. Stellate ganglion innervation of the vertebro-basilar arterial system demonstrated in the rat with anterograde and retrograde WGA-HR tracing
5. Pituitary adenylate cyclase activating polypeptide (PACAP): Discovery and current status of research
6. Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: Neuroendocrine and endocrine interactions
7. Neuropeptides in the human superior cervical ganglion
8. Nitroxidergic innervation of guinea pig cerebral arteries
9. In vitro evidence that vasoactive intestinal peptide is a transmitter of neuro-vasodilation in the head of the cat
10. Appearance of the noradrenergic markers tyrosine hydroxylase and neuropeptide Y in cholinergic nerves of the iris following sympathetomy
11. Perivascular nerves of the human basal cerebral arteries: II. Changes in aging and Alzheimer's disease
12. Perivascular nerves of the human basal cerebral arteries: I. Topographical distribution
13. Localization of nitric oxide synthase indicating a neuronal role for nitric oxide
14. Sympathetic innervation of vascular smooth muscle in normal and hypertensive animals
15. Changes in expression of autonomic nerves in aging and disease
16. Factors involved in physiological regulation of cerebral blood flow
17. Dihydroergotamine and sumatripan attenuate levels of CGRP in plasma in rat superior sagittal sinus during electrical stimulation of the trigeminal ganglion
18. Evidence for coexistence of serotonin and noradrenaline in sympathetic nerves supplying brain vessels of guinea pig
19. 5-HT-containing nerves to major cerebral arteries of the gerbil originate in the superior cervical ganglia
20. Innervation pattern of malformative cortical vessels in Sturge-Weber disease. An histochemical, immunohistochemical and ultrastructural study
21. hCGRP(8-37) a calcitonin gene-related peptide receptor heterogeneity in brain, and periphery
22. Distribution of serotonin-like immunoreactive nerves in major cerebral arteries of rabbit: An immunohistochemical study
23. Substance P in the cerebral vasculature: Depletion by capsaicin suggests a sensory role
24. Concentrations of putative neurovascular transmitters in major cerebral arteries and small pial vessels of various species
25. Concentration of noradrenaline in pial vessels, choroid plexus and iris during two weeks after sympathetic ganglionectomy or decentralization
26. Cholinergic mechanisms in pial vessels. Histochemistry, electron microscopy and pharmacology
27. Autonomic nerves, mast cells and amine receptors in human brain vessels. A histochemical and pharmacological study
28. 3H-noradrenaline into rabbit brain vessels and its relation to the degree of sympathetic supply
29. Substance P: Immunohistochemical localization, and effect upon cat pial arteries in vitro, and in situ
30. Neuropeptide Y: Cerebrovascular innervation, and vasomotor effects in the cat
31. Central serotonergic nerves project to the pial vessels of the brain
32. Substance P. Localization, concentration, and release in cerebral arteries, choroid plexus, and dura mater
33. Neuropeptide Y: Immunocytochemical localization to, and effect upon feline pial arteries, and veins in vitro, and in situ
34. Functional role of perivascular peptides in the control of cerebral circulation
35. Nerve fibres containing neuropeptide Y in the cerebrovascular bed: Immunocytochemistry, radioimmunoassay and vasomotor effects
36. Calcitonin gene-related peptide and cerebral blood vessels: Distribution and vasomotor effects
37. Peptide-containing nerve fibres in human cerebral arteries: Immunocytochemistry, radioimmunoassay and in vitro pharmacology
38. Neurokinin A in cerebral vessels: Characterization, localization, co-existence, and effects in vitro
39. Retrograde tracing of nerve fibers to the rat middle cerebral artery with true blue: Colocalization with different peptides
40. Demonstration of neuropeptide-containing nerves and vasomotor responses to perivascular peptides in human cerebral arteries
41. Calcitonin gene-related peptide1 receptor mRNA in human trigeminal ganglia and cerebral arteries
42. Messenger molecules in the cranial sympathetic nervous system
43. Calcitonin gene-related peptide and nitric oxide in the trigeminal ganglion: Cerebral vasodilation from trigeminal nerve stimulation involves mainly calcitonin gene-related peptide
44. Origin and co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat
45. Amylin: Localization, effects on cerebral arteries and on local cerebral blood flow in the cat
46. The chemical neuroanatomy of sympathetic ganglia
47. Topopgraphy and immunocytochemical characterization of nerve fibres in the leptomeningeal compartments of the rat. A light and electron-microscopical study
48. Perivascular nerves with immunoreactivity to vasoactive intestinal polypeptide in cephalic arteries of the cat: Distribution, possible origins and functional implications
49. Co-existence of immunoreactivity to neuropeptide Y and vasoactive intestinal peptide in non-noradrenergic axons innervating guinea pig cerebral arteries after sympathectomy
50. Release of vasoactive peptide in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system
51. Vasoactive peptide released in the extracerebral circulation of humans during migraine headache
52. The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in human and cats
53. Human in vivo evidence for trigeminovascular activation in cluster headache. Neuropeptide changes and effects of acute therapies
54. Cerebral vasodilation in the cat involves nitric oxide from parasympathetic nerves
55. Ineffectiveness of neurokinin-1 antagonist in acute migraine: A crossover study
56. Neuronal nitric oxide synthase activation by vasoactive intestinal peptide in bovine cerebral arteries
57. Co-localization of neuropeptide tyrosine (NPY), and its C-terminal flanking peptide (C-PON)
58. Simultaneous visualization of neuropeptide and acetylcholinesterase nerve populations in the perivascular plexus
59. Pattern of innervation of sensory afferent systems in the circulation: Immunocytochemistry and ultrastructure
60. Ultrastructural evidence for the coexistence of calcitonin gene-related peptide and substance P in secretory vesicles of peripheral nerves in the guinea pig
61. The peptidergic innervation of human coronary and cerebral vessels
62. Licht und Electronmikroskopishe Untersuchung zur Innervation der Piagefasse
63. Neuropeptide Y mRNA regulation in rat sympathetic ganglia: Effect of reserpine
64. Origin of cholinergic nerves to the rat major arteries: Coexistence with vasoactive intestinal polypeptide
65. Acetylcholine and vasoactive intestinal peptide in cerebral blood vessels: Effect of extirpation of the sphenopalatine ganglion
66. Cerebral blood flow response to carbon dioxide after capsaicin treatment
67. Dopamine β-hydroxylase-, neurotensin-, substance P-, vasoactive intestinal polypeptide-, and enkephalin-immunohistochemistry of paravertebral, and prevertebral ganglia in the cat
68. Substance P is not involved in vascular nociception in humans
69. Dual adrenergic and cholinergic innervation of the cerebral arteries of the rat
70. Ultrastructure of serotonin-containing nerve fibres in the middle cerebral artery of the rat and evidence for its localisation within catecholamine-containing nerve fibres by immunoelectron microscopy
71. 5-Hydroxytryptamine demonstrated immunohistochemically in rat cerebrovascular nerves largely represents 5-hydroxytryptamine uptake into sympathetic nerve fibres
72. Tachykinins (substance P, neurokinin A, neuropeptide K, and neurokinin B) in the cerebral circulation: Vasomotor responses in vitro, and in situ
73. Vasoactive intestinal peptide (VIP) like peptides in the cerebral circulation of the cat
74. The innervation of the human superficial temporal artery
75. Calcitonin gene-related peptide is released from capsaicin-sensitive nerve fibres and induces vasodilation of human cerebral arteries concomitant with activation of adenylate cyclase
76. Somatostatin-like immunoreactivity in human sympathetic ganglia
77. Calcitonin gene-related peptide (human α-CGRP) counteracts vasoconstriction in human subarachnoid haemorrage
78. Calcitonin gene-related peptide-LI in subarachnoid haemorrage in man. Signs of activation of the trigemino-cerebrovascular system?
79. Alterations in perivascular dilatory neuropeptides. (CGRP, SP, VIP) in the external jugular vein and in the cerebrospinal fluid following subarachnoid haemorrage in man
80. Immunohistochemical and electron microscopic demonstration of vascular innervation in the mammalian brain stem
81. Histochemical studies of the adrenergic innervation of canine cerebral arteries
82. Immunohistochemical localization of neuropeptides in the human ciliary ganglion
83. Electrical stimulation of the Gasserian ganglion induced structural alterations of calcitonin gene-related peptide-immunoreactive perivascular sensory nerve terminals in the rat dura mater: Possible model of migraine headache
84. Immunohistochemical localization of a vasodilatory polypeptide (VIP) in cerebrovascular nerves
85. Histamine induces migraine via the H1-receptor. Support for the hypothesis of migraine
86. Direct evidence against acetylcholine as the dilator transmitter in the cat cerebral artery
87. Cholinergic mechanism in the large cat cerebral artery
88. Innervation of cerebral arteries by nerves containing 5-hydroxytryptamine and noradrenaline
89. NPY-, galanin-, VIP/PHI-, CGRP-, and substance P-immunoreactive neuronal subpopulations in cat autonomic, and sensory ganglia, and their projections
90. Immunohistochemical evidence for a substance P-containing trigeminovascular pathway to pial arteries in cats
91. The concept of coupling blood flow to brain function: Revision required?
92. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: Functional significance of coexisting transmitters for vasodilation and secretion
93. Frequency-, and reserpine-dependent chemical coding of sympathetic transmission: Differential release of noradrenaline, and neuropeptide Y from pig spleen
94. Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: Distribution and quantitative differences between the iris and cerebral artery with special reference to substance P
95. Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain
96. Perivascular meningeal projections from cat trigeminal ganglia: Possible pathway for vascular headache in man
97. Calcitonin gene-related peptide: Functional role in cerebrovascular regulation
98. Cholinergic and VIPergic innervation in cerebral arteries: A sequential double-labelling immunohistochemical study
99. Projections of nitric oxide synthase containing fibres from the sphenopalatine ganglion to cerebral arteries in the rat
100. Pituitary adenylate cyclase activating polypeptide is a sensory neuropeptide: Immunocytochemical and immunochemical evidence
101. Pituitary adenylate cyclase activating polypeptide in sensory neurons
102. Pituitary adenylate cyclase activating polypeptide is expressed in autonomic neurons
103. Innervation of i.c. arteries
104. Adrenergic innervation of pial arteries related to the circle of Willis in the cat
105. Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries
106. The nitric oxide hypothesis of migraine and other vascular headaches
107. Autonomic neuroreceptor mechanisms in brain vessels
108. Histochemical and pharmacological approach to the investigation of neurotransmitters, with particular regard to the cerebrovascular bed
109. The non-peptide NK-1 receptor antagonist LY303870 inhibits neurogenic dural inflammation in guinea pigs
110. Substance P-, and calcitonin gene-related peptide-like immunoreactive pericellular baskets in human trigeminal ganglion
111. Calcitonin gene-related peptide in the human trigeminal sensory system at developmental and adult life stages: Immunohistochemistry, neuronal morphometry and coexistence with substance P
112. Serotonin neurons project to small blood vessels in the brain
113. Adrenergic innervation affecting local cerebral blood flow
114. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
115. Evidence for the presence of cholinergic nerves in cerebral arteries: An immunohistochemical demonstration of choline acetyltransferase
116. Serotonin as an alternative transmitter in sympathetic nerves of large cerebral arteries of the rabbit
117. Vasodilator innervation of small cerebral arteries of guinea pigs
118. The effects of pituitary adenylate cyclase-activating polypeptide on cerebral arteries and vertebral artery blood flow in anesthetized dogs
119. The non-peptide neurokinin 1 receptor antagonist RP67580, blocks neurogenic plasma extravasation in the dura mater of rats
120. The NK1 receptor antagonist CP-99,994 blocks dural extravasation, and c-fos expression produced by electrical stimulation of the trigeminal ganglion in rats
121. Comparison of the effects of sumatripan and the NK1 antagonist CP-99,994 on plasma extravasation in dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats
122. Nitric oxide neurons
123. Origins and pathways of cerebrovascular vasoactive intestinal polypeptide-positive nerves in rat
124. Origins and pathways of cerebrovascular nerves storing substance P and calcitonin gene-related peptide in rat
125. Neuropeptide Y co-exists with vasoactive intestinal polypeptide, and acetylcholine in parasympathetic cerebrovascular nerves originating in the sphenopalatine, otic, and internal carotid ganglia of the rat
126. Origins and pathways of choline acetyltransferase-positive parasympathetic nerve fibers to cerebral vessels in rat
127. The cerebrovascular parasympathetic innervation
128. Cerebrovascular NADPH-diaphorase-containing nerve fibers in the rat
129. The human superior cervical ganglion: Neuropeptides and peptide receptors
130. Messenger molecules and receptor mRNA in the human trigeminal ganglion
131. Arterial supersensitivity to nitric oxide (nitroglycerin) in migraine sufferers
132. Distribution of nitric oxide synthase in the human cerebral blood vessels and brain tissues
133. Neuropeptide Y (NPY)-like immunoreactivity in perivascular nerves of the guinea-pig
134. Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: Trigeminal origin and coexistence with substance P
135. PACAP, a VIP-like peptide: Immunohistochemical localization, and effect upon cat pial arteries, and cerebral blood flow
136. Nitric oxide synthase expression in cervical autonomic and sensory ganglia in rat: Relationship to neuropeptides
137. Neuronal messengers and peptide receptors in the human sphenopalatine and otic ganglia
138. Neuropeptide Y-related peptides, and their receptors - Are the receptors potential therapeutic drug targets?
139. Peptidergic innervation of guinea pig brain vessels: Comparison with immunohistochemistry and in vitro pharmacology in rostrally and caudally located arteries
140. Nitric oxide synthase immunoreactive nerve fibres in dog cerebral and peripheral arteries
141. Histological and functional studies on the nitroxidergic nerve innervating monkey cerebral, mesenteric and temporal arteries
142. 5-Hydroxytryptamine-containing fibers in cerebral arteries of the cat, rat, and guinea pig
143. Stimulation of the superior sagittal sinus in the cat causes release of vasoactive peptides
144. Phenotypic plasticity in adult sympathetic neurons: Changes in neuropeptide expression in organ culture