New molecular pathways in angiogenesis

British Journal of Cancer

Volumn 89, Issue 2, 2003, Pages 228-231

  Sullivan, D C ^a   Bicknell, R ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR; EPHRIN; EPHRIN RECEPTOR; NOTCH RECEPTOR; PROTEIN; SLIT PROTEIN; SONIC HEDGEHOG PROTEIN; SPROUTY PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; CANCER; CANCER RESEARCH; DRUG TARGETING; HUMAN; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; SHORT SURVEY; SIGNAL TRANSDUCTION;

EPHRINS; HEDGEHOG PROTEINS; HUMANS; LIGANDS; MEMBRANE PROTEINS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, EPH FAMILY; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 0042622339     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601107     Document Type: Short Survey

References (22)

1. Adams RH (2002) Vascular patterning by Eph receptor tyrosine kinases and Ephrins. Cell Dev Biol 13: 55-60
2. Artavanis-Tsakonas S, Rand MD, Lake RJ (1999) Notch signaling: cell fate control and signal integration in development. Science 284: 770-776
3. Bikfalvi A, Bicknell R (2002) Recent advances in angiogenesis, antiangiogenesis and vascular targeting. Trends Pharmacol Sci 23: 576-580
4. Brantley DM, Cheng N, Thompson EJ, Lin Q, Brekken RA, Thorpe PE, Muraoka RS, Cerretti DP, Pozzi A, Jackson D, Lin C, Chen J (2002) Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. Oncogene 21: 7011-7026
5. Cheng N, Brantley DM, Chen J (2002a) The ephrins and Eph receptors in angiogenesis. Cytokine Growth Factor Rev 13: 75-85
6. Cheng N, Brantley DM, Liu H, Lin Q, Enriquez M, Gale N, Yancopoulos GD, Cerretti DP, Daniel TO, Chen J (2002b) Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis. Mol Cancer Res 1: 2-11
7. Hrabe de Angelis M, McIntyre II J, Gossler A (1997) Maintenance of somite borders in mice requires the Delta homologue DII1. Nature 386: 717-721
8. Huminiecki L, Bicknell R (2000) In silico cloning of novel endothelial-specific genes. Genome Res 10: 1796-1806
9. Huminiecki L, Gorn M, Suchting S, Poulsom R, Bicknell R (2002) Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis. Genomics 79: 547-552
10. Lawson ND, Vogel AM, Weinstein BM (2002) Sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell 3: 127-136
11. Lee SH, Schloss DJ, Jarvis L, Krasnow MA, Swain JL (2001) Inhibition of angiogenesis by a mouse sprouty protein. J Biol Chem 276: 4128-4133
12. Lindner V, Booth C, Prudovsky I, Small D, Maciag T, Liaw L (2001) Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction. Am J Pathol 159: 875-883
13. Liu ZJ, Shirakawa T, Li Y, Soma A, Oka M, Dotto GP, Fairman RM, Velazquez OC, Herlyn M (2003) Regulation of Notch1 and DII4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol 23: 14-25
14. Mailhos C, Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D (2001) Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation 69: 135-144
15. Martiny-Baron G, Wood J, Esser N, Weindel K, Marme D (2001) EphB receptors and Ephrin ligands are involved in tumour growth and angiogenesis in A375 Melanoma Xenografts. Am Assoc Cancer Res Annu Meeting, (Abstract No 4154).
16. Ogawa K, Pasqualini R, Lindberg RA, Kain R, Freeman AL, Pasquale EB (2000) The ephrin-A1 ligand and its receptor, EphA2 are expressed during tumor neovascularization. Oncogene 19: 6043-6052
17. Pandey A, Shao H, Marks RM, Polverini PJ, Dixit VM (1995) Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis. Science 268: 567-569
18. Pola R, Ling LE, Silver M, Corbley MJ, Kearney M, Pepinsky RB, Shapiro R, Taylor FR, Baker DP, Asahara T, Isner JM (2001) The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nat Med 7: 706-711
19. Stein E, Lane AA, Cerretti DP, Schoecklmann HO, Schroff AD, Van Etten RL, Daniel TO (1998) Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses. Genes Dev 12: 667-678
20. Uyttendaele H, Ho J, Rossant J, Kitajewski J (2001) Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad Sci USA 98: 5643-5648
21. Villa N, Walker L, Lindsell CE, Gasson J, Iruela-Arispe ML, Weinmaster G (2001) Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels. Mech Dev 108: 161-164
22. Xue Y, Gao X, Lindsell CE, Norton CR, Chang B, Hicks C, Gendron-Maguire M, Rand EB, Weinmaster G, Gridley T (1999) Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet 8: 723-730