Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction

American Journal of Pathology

Volumn 159, Issue 3, 2001, Pages 875-883

  Lindner, V ^a   Booth, C ^a   Prudovsky, I ^a   Small, D ^a   Maciag, T ^a   Liaw, L ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; PROTEIN JAGGED; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTERY INJURY; ARTICLE; BALLOON CATHETER; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

EID: 0034849519     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)61763-4     Document Type: Article

References (47)

1. Notch signal transduction: A real rip and more
2. Notch signaling: Cell fate control and signal integration in development
3. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
4. Baltimore D: Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
5. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
6. Mutations in the human Jagged1 gene are responsible for Alagille syndrome
7. The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients
8. Notch3 mutations in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASlL), a mendellan condition causing stroke and vascular dementia
9. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
10. Dll4, a novel Notch ligand expressed in arterial endothelium
11. The expression of Jagged 1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome
12. Expression patterns of Notch1, Serrate1, Serrate2 and Delta1 in tissues of the developing chick limb
13. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
14. Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1
15. Notch signaling is essential for vascular morphogenesis in mice
16. Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation
17. A non-transmembrane form of Jagged-1 regulates the formation of matrix-dependent chord-like structures
18. An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitro
19. Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium
20. Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study
21. Urokinase-type plasminogen activator mediates basic fibroblast growth factor-induced bovine endothelial cell migration independent of its proteolytic activity
22. Alphavbeta3 integrin binding affinity and specificity of SM256 in various species
23. The erasable Western blot
24. Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
25. Mechanisms of stenosis after arterial injury
26. Kinetics of cellular proliferation after arterial injury. III. Endothelial and smooth muscle growth in chronically denuded vessels
27. Endothelial regeneration. V. Inhibition of endothelial regrowth in arteries of rat and rabbit
28. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for Src family kinases
29. JAGGED1 gene expression during human embryogenesis elucidates the wide phenotypic spectrum of Alagille syndrome
30. Complementary and combinatorial patterns of Notch gene family expression during early mouse development
31. Jagged2: A serrate-like gene expressed during rat embryogenesis
32. Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development
33. Notch signalling pathway and human diseases
34. Platelet-derived growth factor ligand and receptor expression by large vessel endothelium in vivo
35. Expression of platelet-derived growth factor ligands and receptors by rat aortic endothelium in vivo
36. Processing of the notch ligand delta by the metalloprotease Kuzbanian
37. Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila
38. Immobilization of Notch ligand, Delta-1, is required for induction of Notch signaling
39. Integrin and cadherin synergy regulates contact inhibition of migration and motile activity
40. Role of E-cadherin in peritoneal dissemination of the pancreatic cancer cell line, panc-1, through regulation of cell to cell contact
41. Loss of cell-cell contact is induced by integrin-mediated cell-substratum adhesion in highly-motile and highly-metastatic hepatocellular carcinoma cells
42. The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer
43. The protocadherin PAPC establishes segmental boundaries during somitogenesis in Xenopus embryos
44. Mouse paraxial protocadherin is expressed in trunk mesoderm and is not essential for mouse development
45. Expression of an activated Notch4(int-3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro
46. Notch4 and Jagged-1 induce microvessel differentiation of rat brain endothelial cells
47. Soluble Jagged1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype