In silico cloning of novel endothelial-specific genes

Genome Research

Volumn 10, Issue 11, 2000, Pages 1796-1806

  Huminiecki, L ^a   Bicknell, R ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; CD31 ANTIGEN; COLLAGEN TYPE 4; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR; FATTY ACID BINDING PROTEIN; PHOSPHATIDYLSERINE; PROTEIN TYROSINE KINASE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VON WILLEBRAND FACTOR;

ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DATA BASE; DRUG TARGETING; ENDOTHELIUM CELL; EXPRESSED SEQUENCE TAG; GENE CLUSTER; GENE LIBRARY; GENE SEQUENCE; GENE TARGETING; HUMAN; HUMAN CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE SPECIFICITY; VASCULAR ENDOTHELIUM;

ADULT; ANIMALS; CELL LINE; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; DATABASES, FACTUAL; DNA, NEOPLASM; ENDOTHELIUM; EXPRESSED SEQUENCE TAGS; FEMALE; GENE EXPRESSION; GENE LIBRARY; HUMANS; MALE; MICE; MULTIGENE FAMILY; SOFTWARE; TUMOR CELLS, CULTURED;

EID: 0033669849     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.150700     Document Type: Article

References (51)

1. Toward the development of a gene index to the human genome: An assessment of the nature of high-throughput EST sequence data
2. Initial assessment of human gene diversity and expression patterns based on 83 million nucleotides of cDNA sequence
3. Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
4. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins
5. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
6. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
7. Chimeric axon guidance receptors: The cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion
8. Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells
9. Characterization of the human fovea cDNA library and regional differential gene expression in the human retina
10. Biosequence exegesis
11. ESTablishing a human transcript map
12. The human adult skeletal muscle transcriptional profile reconstructed by a novel computational approach
13. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
14. Characterization of gene expression in resting and activated mast cells
15. Localization of VEGF and expression of its receptors flt and KDR in human placenta throughout pregnancy
16. The genetics of cancer-a 3D model
17. Prediction of transmembrane α-helices in prokaryotic membrane proteins: The dense alignment surface method
18. Functional gene expression domains: Defining the functional unit of eukaryotic gene regulation
19. Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: A candidate for 6q-linked retinopathies
20. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
21. It's the genes! EST access to human genome content
22. Human von Willebrand factor (vWF): Isolation of complementary DNA (cDNA) clones and chromosomal localization
23. Multimerin is found in the α-granules of resting platelets and is synthesized by a megakaryocytic cell line
24. Studies of multimerin in human endothelial cells
25. An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect
26. Membrane Protein Structure Prediction, Hydrophobicity Analysis and the Positive-inside Rule
27. Expression profile of active genes in granulocytes
28. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors
29. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit
30. Identification of human megakaryocyte coagulation factor V
31. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
32. Vascular endothelial growth factor and its receptors in male fertility
33. A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains
34. The molecular characterization of the fetal stem cell marker AA4
35. Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system
36. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
37. Pieces of the puzzle: Expressed sequence tags and the catalog of human genes
38. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
39. cDNA encoding novel polypeptide from human umbilical vein endothelial cell
40. Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family
41. Identification of common molecular subsequences
42. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
43. Biosynthesis of von Willebrand protein by human megakaryocytes
44. New opportunities for uncovering the molecular basis of cancer
45. Hematopoiesis and angiogenesis
46. cDNA cloning and gene expression of human type 1-α cGMP-dependent protein kinase
47. Discovery of three genes specifically expressed in human prostate by expressed sequence tag database analysis
48. Serial analysis of gene expression
49. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2
50. Inventory of high-abundance mRNAs in skeletal muscle of normal men
51. KDR receptor: A key marker defining hematopoietic stem cells