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Volumn 54, Issue 2, 2003, Pages 203-218

The molecular mechanisms of cellular tolerance to δ-opioid agonists: A minireview

Author keywords

Adenylyl cyclase phosphorylation; Adenylyl cyclase superactivation; Cellular tolerance; Human opioid receptor; Receptor down regulation

Indexed keywords

4 (ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL) N,N DIETHYLBENZAMIDE; 4-(ALPHA-(4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL)-N,N-DIETHYLBENZAMIDE; ADENYLATE CYCLASE; BENZAMIDE DERIVATIVE; CYCLIC AMP; DELTA OPIATE RECEPTOR; NARCOTIC ANALGESIC AGENT; PIPERAZINE DERIVATIVE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

EID: 0042286663     PISSN: 02365383     EISSN: None     Source Type: Journal    
DOI: 10.1556/ABiol.54.2003.2.9     Document Type: Short Survey
Times cited : (5)

References (46)
  • 1
    • 0031886497 scopus 로고    scopus 로고
    • Role of carboxyl terminus of μ and δ opioid receptor in agonist-induced down-regulation
    • Afify, E. A., Law, P. Y., Riedl, M., Elde, R., Loh, H. H. (1998) Role of carboxyl terminus of μ and δ opioid receptor in agonist-induced down-regulation. Mol. Brain Res. 54, 24-34.
    • (1998) Mol. Brain Res. , vol.54 , pp. 24-34
    • Afify, E.A.1    Law, P.Y.2    Riedl, M.3    Elde, R.4    Loh, H.H.5
  • 3
    • 0034029962 scopus 로고    scopus 로고
    • Alterations in detergent solubility of heterotrimeric G proteins after chronic activation of Gi/o-coupled receptors: Changes in detergent solubility are in correlation with onset of adenylyl cyclase superactivation
    • Bayewitch, M. L., Nevo, I., Avidor-Reiss, T., Levy, R., Simmonds, W. F., Vogel, Z. (2000) Alterations in detergent solubility of heterotrimeric G proteins after chronic activation of Gi/o-coupled receptors: Changes in detergent solubility are in correlation with onset of adenylyl cyclase superactivation. Mol. Pharmacol. 57, 820-825.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 820-825
    • Bayewitch, M.L.1    Nevo, I.2    Avidor-Reiss, T.3    Levy, R.4    Simmonds, W.F.5    Vogel, Z.6
  • 4
    • 0035823506 scopus 로고    scopus 로고
    • Mu opioid receptor-mediated ERK activation involves calmodulin dependent EGF receptor transactivation
    • Belcheva, M. M., Szücs, M., Wang, D., Sadee, W., Coscia, C. J. (2001) Mu opioid receptor-mediated ERK activation involves calmodulin dependent EGF receptor transactivation. J. Biol. Chem. 276, 33847-33853.
    • (2001) J. Biol. Chem. , vol.276 , pp. 33847-33853
    • Belcheva, M.M.1    Szücs, M.2    Wang, D.3    Sadee, W.4    Coscia, C.J.5
  • 5
    • 0036364093 scopus 로고    scopus 로고
    • Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase
    • Belcheva, M. M., Coscia, C. J. (2002) Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase. Neurosignals 11, 34-44.
    • (2002) Neurosignals , vol.11 , pp. 34-44
    • Belcheva, M.M.1    Coscia, C.J.2
  • 6
    • 0031059468 scopus 로고    scopus 로고
    • Regulatory mechanisms that modulate signaling by G protein-coupled receptors
    • Bohm, S. K., Grady, E. F., Bunett, N. W. (1997) Regulatory mechanisms that modulate signaling by G protein-coupled receptors. Biochem. J. 322, 1-35.
    • (1997) Biochem. J. , vol.322 , pp. 1-35
    • Bohm, S.K.1    Grady, E.F.2    Bunett, N.W.3
  • 7
    • 0032422655 scopus 로고    scopus 로고
    • Chronic morphine augments adenylyl cyclase phosphorylation: Relevance to altered signaling during tolerance/dependence
    • Chakrabarti, S., Wang, L., Tang, W.-J., Gintzler, A. R. (1998) Chronic morphine augments adenylyl cyclase phosphorylation: relevance to altered signaling during tolerance/dependence. Mol. Pharmacol. 54, 949-953.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 949-953
    • Chakrabarti, S.1    Wang, L.2    Tang, W.-J.3    Gintzler, A.R.4
  • 8
    • 0035853752 scopus 로고    scopus 로고
    • Proteasome involvement in agonist-induced down-regulation of the μ and δ-opioid receptors
    • Chaturvedi, K., Bandari, P., Chinen, N., Howells, R. D. (2001) Proteasome involvement in agonist-induced down-regulation of the μ and δ-opioid receptors. J. Biol. Chem. 276, 12345-12352.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12345-12352
    • Chaturvedi, K.1    Bandari, P.2    Chinen, N.3    Howells, R.D.4
  • 9
    • 0029671452 scopus 로고    scopus 로고
    • 353, located within the COOH-terminal tail of the δ opiate receptor, is involved in receptor down-regulation
    • 353, located within the COOH-terminal tail of the δ opiate receptor, is involved in receptor down-regulation. J. Biol. Chem. 271, 4073-4079.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4073-4079
    • Cvejic, S.1    Trapaidze, N.2    Cyr, C.3    Devi, L.A.4
  • 10
    • 0031712776 scopus 로고    scopus 로고
    • Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GMI ganglioside-regulated opioid receptor functions
    • Crain, S. M., Shen, S.-F. (1998) Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GMI ganglioside-regulated opioid receptor functions. Trends Pharmacol. Sci. 19, 358-365.
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 358-365
    • Crain, S.M.1    Shen, S.-F.2
  • 11
    • 0032706897 scopus 로고    scopus 로고
    • Human dopamine D3 receptors mediate MAP kinase activation via PI-3-kinase and an atypical protein kinase C dependent mechanism
    • Cussack, D., Newman-Tancredi, A., Pasteau, V., Millan, M. J. (1999) Human dopamine D3 receptors mediate MAP kinase activation via PI-3-kinase and an atypical protein kinase C dependent mechanism. Mol. Pharmacol. 56, 1025-1030.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 1025-1030
    • Cussack, D.1    Newman-Tancredi, A.2    Pasteau, V.3    Millan, M.J.4
  • 12
    • 0029799611 scopus 로고    scopus 로고
    • Functional coupling of δ, μ, and κ-opioid receptors to MAP kinase and arachidonate release in Chinese hamster ovary cells
    • Fukuda, K., Kato, S., Morikawa, H., Shoda, T., Mori, K. (1996) Functional coupling of δ, μ, and κ-opioid receptors to MAP kinase and arachidonate release in Chinese hamster ovary cells. J. Neurochem. 67, 1309-1316.
    • (1996) J. Neurochem. , vol.67 , pp. 1309-1316
    • Fukuda, K.1    Kato, S.2    Morikawa, H.3    Shoda, T.4    Mori, K.5
  • 13
    • 0030700220 scopus 로고    scopus 로고
    • Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins
    • Hicke, L. (1997) Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins. The FASEB J. 11, 1215-1234.
    • (1997) The FASEB J. , vol.11 , pp. 1215-1234
    • Hicke, L.1
  • 14
  • 15
    • 0037040389 scopus 로고    scopus 로고
    • Opioid tolerance - In search of the holy grail
    • Kieffer, B. L., Evans, C. J. (2002) Opioid tolerance - in search of the holy grail. Cell 108, 587-590.
    • (2002) Cell , vol.108 , pp. 587-590
    • Kieffer, B.L.1    Evans, C.J.2
  • 17
    • 0032902147 scopus 로고    scopus 로고
    • Role of protein kinase C in agonist-induced μ-opioid receptor down-regulation: II. Activation and involvement of the α, ε and ξ isoforms of PKC
    • Kramer, H. K., Simon, E. J. (1999) Role of protein kinase C in agonist-induced μ-opioid receptor down-regulation: II. Activation and involvement of the α, ε and ξ isoforms of PKC. J. Neurochem. 72, 594-604.
    • (1999) J. Neurochem. , vol.72 , pp. 594-604
    • Kramer, H.K.1    Simon, E.J.2
  • 18
    • 0022403798 scopus 로고
    • Effect of pertussis toxin treatment on the down-regulation of opiate receptors in neuroblastoma x glioma NG108-15 hybrid cells
    • Law, P.-Y., Louie, A. K., Loh, H. H. (1985) Effect of pertussis toxin treatment on the down-regulation of opiate receptors in neuroblastoma x glioma NG108-15 hybrid cells. J. Biol. Chem. 260, 14818-14822.
    • (1985) J. Biol. Chem. , vol.260 , pp. 14818-14822
    • Law, P.-Y.1    Louie, A.K.2    Loh, H.H.3
  • 19
    • 0027315891 scopus 로고
    • Delta opioid receptor activates cAMP phosphodiesterase activities in neuroblastoma x glioma NG108-15 hybrid cells
    • Law, P.-Y., Loh, H. H. (1993) Delta opioid receptor activates cAMP phosphodiesterase activities in neuroblastoma x glioma NG108-15 hybrid cells. Mol. Pharmacol. 43, 684-693.
    • (1993) Mol. Pharmacol. , vol.43 , pp. 684-693
    • Law, P.-Y.1    Loh, H.H.2
  • 20
    • 0033495801 scopus 로고    scopus 로고
    • Mutational analysis of the structure and function of opioid receptors
    • Law, P.-Y., Wong, Y. H., Loh, H. H. (1999) Mutational analysis of the structure and function of opioid receptors. Biopolymers 51, 440-457.
    • (1999) Biopolymers , vol.51 , pp. 440-457
    • Law, P.-Y.1    Wong, Y.H.2    Loh, H.H.3
  • 21
    • 0034711224 scopus 로고    scopus 로고
    • Hierarchical phosphorylation of δ-opioid receptor regulates agonist-induced receptor desensitization and internalization
    • Maestri-El Kouhen, O., Wang, G., Solberg, J., Erickson, L. J., Law, P.-Y., Loh, H. H. (2000) Hierarchical phosphorylation of δ-opioid receptor regulates agonist-induced receptor desensitization and internalization. J. Biol. Chem. 275, 36659-36664.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36659-36664
    • Maestri-El Kouhen, O.1    Wang, G.2    Solberg, J.3    Erickson, L.J.4    Law, P.-Y.5    Loh, H.H.6
  • 22
    • 0030431224 scopus 로고    scopus 로고
    • Human delta opioid receptor: Functional studies on stably transfected Chinese hamster ovary cells after acute and chronic treatment with the selective nonpeptidic agonist SNC-80
    • Malatynska, E., Wang, Y., Knapp, R. J., Waite, S., Calderon, S., Rice, K., Hruby, V. J., Yamamura, H. I., Roeske, W. R. (1996) Human delta opioid receptor: Functional studies on stably transfected Chinese hamster ovary cells after acute and chronic treatment with the selective nonpeptidic agonist SNC-80. J. Pharmacol. Exp. Ther. 278, 1083-1094.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 1083-1094
    • Malatynska, E.1    Wang, Y.2    Knapp, R.J.3    Waite, S.4    Calderon, S.5    Rice, K.6    Hruby, V.J.7    Yamamura, H.I.8    Roeske, W.R.9
  • 23
    • 0029752791 scopus 로고    scopus 로고
    • Endocytosis and molecular sorting
    • Mellman, I. (1996) Endocytosis and molecular sorting. Ann. Rev. Cell. Dev. Biol. 12, 575-592.
    • (1996) Ann. Rev. Cell. Dev. Biol. , vol.12 , pp. 575-592
    • Mellman, I.1
  • 24
    • 0030609874 scopus 로고    scopus 로고
    • Synergistic regulation of β2-adrenergic receptor sequestration: Intracellular complement of β-adrenergic receptor kinase and β-arrestin determine kinetics of internalization
    • Menard, L., Ferguson, S. S. G., Zhang, J., Lin, F.-T., Lefkowitz, R. J., Caron, M. G., Barak, L. S. (1997) Synergistic regulation of β2-adrenergic receptor sequestration: Intracellular complement of β-adrenergic receptor kinase and β-arrestin determine kinetics of internalization. Mol. Pharmacol. 51, 800-808.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 800-808
    • Menard, L.1    Ferguson, S.S.G.2    Zhang, J.3    Lin, F.-T.4    Lefkowitz, R.J.5    Caron, M.G.6    Barak, L.S.7
  • 25
    • 0032875356 scopus 로고    scopus 로고
    • Physiological regulation of G protein linked signaling
    • Morris, A. J., Malbon, C. C. (1999) Physiological regulation of G protein linked signaling. Physiol. Rev. 79, 1373-1430.
    • (1999) Physiol. Rev. , vol.79 , pp. 1373-1430
    • Morris, A.J.1    Malbon, C.C.2
  • 26
    • 0032566523 scopus 로고    scopus 로고
    • Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor
    • Murray, S. R., Evans, C. J., von Zastrow, M. (1998) Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor. J. Biol. Chem. 273, 24987-24996.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24987-24996
    • Murray, S.R.1    Evans, C.J.2    Von Zastrow, M.3
  • 29
    • 0029085874 scopus 로고
    • Agonist-dependent phosphorylation of the mouse δ-opioid receptor: Involvement of G protein-coupled receptor kinases but not protein kinase C
    • Pei, G., Kieffer, B. L., Lefkowitz, R. J., Freedman, R. D. (1995) Agonist-dependent phosphorylation of the mouse δ-opioid receptor: Involvement of G protein-coupled receptor kinases but not protein kinase C. Mol. Pharmacol. 48, 173-178.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 173-178
    • Pei, G.1    Kieffer, B.L.2    Lefkowitz, R.J.3    Freedman, R.D.4
  • 31
    • 0025960130 scopus 로고
    • Development of delta opioid peptides as non-addicting analgesics
    • Rapaka, R. S., Porreca, F. (1991) Development of delta opioid peptides as non-addicting analgesics. Pharm. Res. 8, 1-8.
    • (1991) Pharm. Res. , vol.8 , pp. 1-8
    • Rapaka, R.S.1    Porreca, F.2
  • 32
    • 0031933356 scopus 로고    scopus 로고
    • Differential effect of chronic morphine on mRNA encoding adenylyl cyclase isoforms: Relevance to physiological sequela of tolerance/dependence
    • Rivera, M., Ginzler, A. R. (1998) Differential effect of chronic morphine on mRNA encoding adenylyl cyclase isoforms: relevance to physiological sequela of tolerance/dependence. Mol. Brain Res. 54, 165-169.
    • (1998) Mol. Brain Res. , vol.54 , pp. 165-169
    • Rivera, M.1    Ginzler, A.R.2
  • 33
    • 0034752836 scopus 로고    scopus 로고
    • Expression of α-transducin in Chinese hamster ovary cells stably transfected with the human δ-opioid receptor attenuates agonist-induced adenylyl cyclase superactivation
    • Rubenzik, M., Varga, E. V., Stropova, D., Roeske, W. R., Yamamura, H. I. (2001) Expression of α-transducin in Chinese hamster ovary cells stably transfected with the human δ-opioid receptor attenuates agonist-induced adenylyl cyclase superactivation. Mol. Pharmacol. 60, 1076-1082.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1076-1082
    • Rubenzik, M.1    Varga, E.V.2    Stropova, D.3    Roeske, W.R.4    Yamamura, H.I.5
  • 34
    • 0011276168 scopus 로고
    • Dual regulation of adenylyl cyclase accounts for narcotic dependence and tolerance
    • Sharma, S. K., Klee, W. A., Nirenberg, M. (1975) Dual regulation of adenylyl cyclase accounts for narcotic dependence and tolerance. Proc. Natl. Acad. Sci. USA 72, 3092-3096.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 3092-3096
    • Sharma, S.K.1    Klee, W.A.2    Nirenberg, M.3
  • 36
    • 0029928241 scopus 로고    scopus 로고
    • Isoform-specific sensitization of adenylyl cyclase activity by prior activation of inhibitory receptors: Role of βγ subunits in transducing enhanced activity of the type VI isoform
    • Thomas, J. M., Hoffman, B. B. (1996) Isoform-specific sensitization of adenylyl cyclase activity by prior activation of inhibitory receptors: Role of βγ subunits in transducing enhanced activity of the type VI isoform. Mol. Pharmacol. 49, 907-914.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 907-914
    • Thomas, J.M.1    Hoffman, B.B.2
  • 37
    • 0029825797 scopus 로고    scopus 로고
    • Sequestration of the δ-opioid receptor, role of the C terminus in agonist-mediated internalization
    • Trapaidze, N., Keith, D. E., Cvejic, S., Evans, C. J., Devi, L. A. (1996) Sequestration of the δ-opioid receptor, role of the C terminus in agonist-mediated internalization. J. Biol. Chem. 271, 29279-29286.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29279-29286
    • Trapaidze, N.1    Keith, D.E.2    Cvejic, S.3    Evans, C.J.4    Devi, L.A.5
  • 38
    • 0035063380 scopus 로고    scopus 로고
    • Mechanisms of opioid-induced pain and antinociceptive tolerance: Descending facilitation and spinal dynorphin
    • Vanderah, T. W., Ossipov, M. H., Lai, J., Malan, T. P. Jr., Porreca, F. (2001) Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin. Pain 92, 5-9.
    • (2001) Pain , vol.92 , pp. 5-9
    • Vanderah, T.W.1    Ossipov, M.H.2    Lai, J.3    Malan T.P., Jr.4    Porreca, F.5
  • 39
    • 0026091933 scopus 로고
    • μ-Opioid receptor-regulated adenylate cyclase activity in primary cultures of rat striatal neurons upon chronic morphine exposure
    • van Vliet, B. J., DeVries, T. J., Wardeh, G., Mulder, A. H., Schoffelmeer, A. N. M. (1991) μ-Opioid receptor-regulated adenylate cyclase activity in primary cultures of rat striatal neurons upon chronic morphine exposure. Eur. J. Pharmacol. 208, 105-111.
    • (1991) Eur. J. Pharmacol. , vol.208 , pp. 105-111
    • Van Vliet, B.J.1    DeVries, T.J.2    Wardeh, G.3    Mulder, A.H.4    Schoffelmeer, A.N.M.5
  • 44
    • 0033179904 scopus 로고    scopus 로고
    • Functional dissociation of μ opioid receptor signaling and endocytosis: Implications for the biology of opiate tolerance and addiction
    • Whistler, J. L., Chuang, H.-H., Chu, P., Jan, L.-Y., von Zastrow, M. (1999) Functional dissociation of μ opioid receptor signaling and endocytosis: Implications for the biology of opiate tolerance and addiction. Neuron 23, 737-749.
    • (1999) Neuron , vol.23 , pp. 737-749
    • Whistler, J.L.1    Chuang, H.-H.2    Chu, P.3    Jan, L.-Y.4    Von Zastrow, M.5
  • 45
    • 0035138995 scopus 로고    scopus 로고
    • Cellular and synaptic adaptations mediating opioid dependence
    • Williams, J. T., Christie, M. J., Manzoni, O. (2001) Cellular and synaptic adaptations mediating opioid dependence. Physiol. Rev. 81, 299-343.
    • (2001) Physiol. Rev. , vol.81 , pp. 299-343
    • Williams, J.T.1    Christie, M.J.2    Manzoni, O.3
  • 46
    • 0031559870 scopus 로고    scopus 로고
    • Carboxyl terminus of delta opioid receptor is required for agonist-dependent receptor phosphorylation
    • Zhao, J., Pei, G., Huang, Y. L., Zhong, F. M., Ma, L. (1997) Carboxyl terminus of delta opioid receptor is required for agonist-dependent receptor phosphorylation. Biochem. Biophys. Res. Commun. 238, 71-76.
    • (1997) Biochem. Biophys. Res. Commun. , vol.238 , pp. 71-76
    • Zhao, J.1    Pei, G.2    Huang, Y.L.3    Zhong, F.M.4    Ma, L.5


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