Enhanced stimulatory adenylyl cyclase signaling during opioid dependence is associated with a reduction in palmitoylated G(sα)

Molecular Pharmacology

Volumn 52, Issue 6, 1997, Pages 993-999

  Ammer, Hermann ^a   Schulz, Rüdiger ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; OPIATE;

ADAPTATION; ARTICLE; DRUG DEPENDENCE; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RECONSTITUTION; HUMAN; HUMAN CELL; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN PROCESSING; SECOND MESSENGER; SENSITIZATION; SIGNAL TRANSDUCTION;

EID: 0031435934     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.52.6.993     Document Type: Article

References (39)

1. Collier, H. O. J. Cellular site of opiate dependence. Nature (Lond.) 283: 625-629 (1980).
2. Nestler, E. J., Hope, B. T., and K. L. Widnell. Drug addiction: a model for the molecular basis of neural plasticity. Neuron 11:995-1006 (1993).
3. Sharma, S. K., Klee, W. A., and M. Nirenberg. Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance. Proc. Natl. Acad. Sci. USA 72:3092-3096 (1975).
4. Johnson, S. M., and W. W. Fleming. Mechanisms of cellular adaptive sensitivity changes: applications to opioid tolerance and dependence. Pharmacol. Rev. 41:435-488 (1989).
5. Reisine, T., and G. I. Bell. Molecular biology of opioid receptors. Trends Neurosci. 19:506-510 (1993).
6. Sharma, S. K., Nirenberg, M., and W. A. Klee. Morphine receptors as regulators of adenylate cyclase activity. Proc. Natl. Acad. Sci. USA 72: 590-594 (1975).
7. 1 receptors and stimulatory G proteins. Brain Res. 707:265-244 (1996).
8. Ammer, H., and R. Schulz. Chronic morphine treatment increases stimulatory beta-2 adrenoceptor signaling in A431 cells stably expressing the mu opioid receptor. J. Pharmacol. Exp. Ther. 280:512-520 (1997).
9. Yu, V. C., Eiger, S., Duan, D.-S., Lameh, J., and W. Sadée. Regulation of cyclic AMP by the mu opioid receptor in human neuroblastoma SH-SY5Y cells. J. Neurochem. 55:1390-1396 (1990).
10. Nestler, E. J. Molecular mechanisms of drug addiction. J. Neurosci. 12: 2439-2450 (1992).
11. 1 receptor system in neuroblastoma X glioma (NG108-15) hybrid cells. J. Neurochem. 64:2449-2457 (1995).
12. Gilman, A. G. G-proteins: transducers of receptor generated signals. Annu. Rev. Biochem. 56:615-649 (1987).
13. α subunits with the plasma membrane. Current Biol. 5:107-109 (1995).
14. Mollner, S., Beck, K., and T. Pfeuffer. Acylation of adenylyl cyclase catalyst is important for enzymic activity. FEBS Lett. 371:241-244 (1995).
15. 2-adrenergic receptor by the cAMP-dependent protein kinase. J. Biol. Chem. 271:21490-21497 (1996).
16. 3H] palmitic acid and mutation of cysteine-3 prevents this modification. Biochemistry 32:8057-8061 (1993).
17. sα. J. Biol. Chem. 268:25001-25008 (1993).
18. Mumby, S. M., Kleuss, C., and A. G. Gilman. Receptor regulation of G-protein palmitoylation. Proc. Natl. Acad. Sci. USA 91:2800-2804 (1994).
19. s protein α subunit after activation by the β-adrenergic receptor or cholera toxin. J. Biol. Chem. 268:23769-23772 (1993).
20. sα. Cell 77:1063-1070 (1994).
21. sα. Mol. Cell. Biol. 7:1225-1233 (1996).
22. Delavier-Klutchko, C., Hoebecke, J., and D. Strosberg. The human carcinoma cell line A431 possesses large numbers of functional β-adrenergic receptors. FEBS Lett. 169:151-155 (1984).
23. Chen, Y., Mestek, A., Liu, J., Hurley, J. A., and L. Yu. Molecular cloning and functional expression of a μ-opioid receptor from rat brain. Mol. Pharmacol. 44:8-12 (1993).
24. Vachon, L., Costa, T., and A. Herz. GTPase and adenylate cyclase desensitize at different rates in NG108-15 cells. Mol. Pharmacol. 31:159-168 (1987).
25. Bourne, H. R., Coffino, P., and G. M. Tomkins. Selection of a variant lymphoma cell deficient in adenylate cyclase. Science (Washington D. C.) 187:750-752 (1975).
26. Frandsen, E. K., and G. Krishna. A simple ultrasensitive method for the assay of cyclic AMP and cyclic GMP in tissues. Life Sci. 18:529-542 (1977).
27. Sternweis, P. C., Northup, J. K., Smigel, M. D., and A. G. Gilman. The regulatory component of adenylate cyclase: purification and properties. J. Biol. Chem. 256:11517-11526 (1981).
28. Pepperberg, D. R., Morrison, D. F., and P. J. O'Brien. Depalmitoylation of rhodopsin with hydroxylamine. Methods Enzymol. 250:348-361 (1995).
29. Patterson, S. I., and P. J. H. Skene. Inhibition of dynamic protein palmitoylation in intact cells with tunicamycin. Methods Enzymol. 250:284-299 (1995).
30. z signaling. J. Biol. Chem. 270:9667-9675 (1995).
31. s-adenylate cyclase interactions. FASEB J. 5:2300-2303 (1991).
32. s) and adenylyl cyclase. J. Neurochem. 64:724-732 (1995).
33. s to rat synaptic membrane adenylate cyclase is enhanced subsequent to chronic antidepressant treatment. Mol. Pharmacol. 36:803-808 (1989).
34. Chen, J., Carty, D. J., and R. Iyengar. Adenylyl cyclase assay for βγ subunits of G proteins. Methods Enzymol. 237:451-456 (1994).
35. Resh, M. D. Myristylation and palmitylation of src family members: the fats of the matter. Cell 76:411-413 (1994).
36. Dunphy, J. T., Greentree, W. K., Manahan, C. L., and M. E. Linder. G-protein palmitoyltransferase activity is enriched in plasma membranes. J. Biol. Chem. 271:7154-7159 (1996).
37. sα by palmitate and the βγ subunit. Proc. Natl. Acad. Sci. USA 93:14592-14597 (1996).
38. Thomas, J. M., and B. B. Hoffman. Isoform-specific sensitization of adenylyl cyclase activity by prior activation of inhibitory receptors: role of βγ subunits in transducing enhanced activity of the type VI isoform. Mol. Pharmacol. 49:907-914 (1996).
39. Lisanti, M. P., Scherer, P. E., Tang, Z. L., and M. Sargiacomo. Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis. Trends Cell Biol. 4:231-235 (1994).