Phosphorylation of adenylyl cyclase VI upon chronic δ-opioid receptor stimulation

European Journal of Pharmacology

Volumn 364, Issue 2-3, 1999, Pages

  Varga, Eva V ^a   Stropova, Dagmar ^a   Rubenzik, Marc ^a   Waite, Sue ^a   Roeske, William R ^a   Yamamura, Henry I ^a  

^a NONE

Author keywords

Adenylyl cyclase VI; Opioid receptor; Phosphorylation

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; ADENYLATE CYCLASE; DELTA OPIATE RECEPTOR; NALTRINDOLE; PHOSPHATE;

ANIMAL CELL; CELL CULTURE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SHORT SURVEY;

EID: 0032899678     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00847-4     Document Type: Article

References (8)

1. Avidor-Reiss T., Nevo I., Levy R., Pfeuffer T., Vogel Z. Chronic opioid treatment induces adenylyl cyclase V superactivation. J. Biol. Chem. 271:1996;21309-21315.
2. Avidor-Reiss T., Nevo I., Saya D., Bayewitz M., Vogel Z. Opiate-induced adenylyl cyclase superactivation is isoenzyme-specific. J. Biol. Chem. 272:1997;5040-5047.
3. βγ interactions with PH domains and Ras-MAPK signaling pathways. Trends Biochem. 20:1995;151-156.
4. Ishikawa Y., Homcy C.J. The adenylyl cyclases as integrators of the transmembrane signal transduction pathway. Circulation Research. 80:1997;297-304.
5. Malatynska E., Wang Y., Knapp R.J., Waite S., Calderon S., Rice K., Hruby V.J., Yamamura H.I., Roeske W.R. Human delta opioid receptor: functional studies on stably transfected CHO cells following acute and chronic treatment with the selective non-peptidic agonist SNC-80. J. Pharmacol. Exp. Ther. 278:1995;1083-1089.
6. Mons N., Cooper D.M.F. Adenylate cyclases: critical foci in neuronal signaling. Trends Neurosci. 18:1995;536-542.
7. Sharma S.K., Klee W.A., Nirenberg M. Dual regulation of adenylyl cyclase accounts for narcotic dependence and tolerance. Proc. Natl. Acad. Sci. USA. 72:1975;3092-3096.
8. Varga E.V., Stropova D., Rubenzik M., Wang M., Landsman R.S., Roeske W.R., Yamamura H.I. Identification of adenylyl cyclase isoenzymes in CHO and B82 cells. Eur. J. Pharmacol. 348:1998;R1-R2.