-
1
-
-
0024532122
-
Inhibition of potentially lethal DNA damage repair in human tumor cells by β-lapachone, an activator of topoisomerase I
-
Boothman DA, Trask DK, Pardee AB (1989). Inhibition of potentially lethal DNA damage repair in human tumor cells by β-lapachone, an activator of topoisomerase I. Cancer Res 49: 605-612.
-
(1989)
Cancer Res
, vol.49
, pp. 605-612
-
-
Boothman, D.A.1
Trask, D.K.2
Pardee, A.B.3
-
2
-
-
0032031888
-
Involvement of hydrogen peroxide in topoisomerase inhibitor β-lapachone-induced apoptosis and differentiation in human leukemia cells
-
Chau Y-P, Shiah S-G, Con M-J, Kuo M-L (1998). Involvement of hydrogen peroxide in topoisomerase inhibitor β-lapachone-induced apoptosis and differentiation in human leukemia cells. Free Radical Biol Med 24: 660-670.
-
(1998)
Free Radical Biol Med
, vol.24
, pp. 660-670
-
-
Chau, Y.-P.1
Shiah, S.-G.2
Con, M.-J.3
Kuo, M.-L.4
-
3
-
-
0033795435
-
Inhibition of tert-butyl hydroperoxide-induced cell membrane bleb formation by alphatocopherol and glutathione
-
Chen HW, Chlang T, Wang CY, Lii CK (2000). Inhibition of tert-butyl hydroperoxide-induced cell membrane bleb formation by alphatocopherol and glutathione. Food Chem Toxicol 38: 1089-1096.
-
(2000)
Food Chem Toxicol
, vol.38
, pp. 1089-1096
-
-
Chen, H.W.1
Chlang, T.2
Wang, C.Y.3
Lii, C.K.4
-
4
-
-
0027218533
-
The production of chromosomal alterations by β-lapachone, an activator of topoisomerase I
-
Degrassi F, De Salvia R, Berghella L (1993). The production of chromosomal alterations by β-lapachone, an activator of topoisomerase I. Mutat Res 288: 263-267.
-
(1993)
Mutat Res
, vol.288
, pp. 263-267
-
-
Degrassi, F.1
De Salvia, R.2
Berghella, L.3
-
5
-
-
0031870525
-
Effect of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agents
-
Dolan ME, Frydman B, Thompson CB, Diamond AM, Garbiras BJ, Safa AR, Beck WT, Marton LJ (1998). Effect of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agents. Anti-cancer Drugs 9: 437-448.
-
(1998)
Anti-cancer Drugs
, vol.9
, pp. 437-448
-
-
Dolan, M.E.1
Frydman, B.2
Thompson, C.B.3
Diamond, A.M.4
Garbiras, B.J.5
Safa, A.R.6
Beck, W.T.7
Marton, L.J.8
-
6
-
-
0035056968
-
Induction of CDK inhibitors (p21 WAF1 and p27Kip1) and Bak in the β-lapachone induced apoptosis of human prostate cancer cells
-
Don M-J, Chang Y-H, Chen K-K, Ho L-K, Chau Y-P (2001). Induction of CDK inhibitors (p21 WAF1 and p27Kip1) and Bak in the β-lapachone induced apoptosis of human prostate cancer cells. Mol Pharmacol 59: 784-794.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 784-794
-
-
Don, M.-J.1
Chang, Y.-H.2
Chen, K.-K.3
Ho, L.-K.4
Chau, Y.-P.5
-
7
-
-
0033641615
-
Muerte celular programada y apoptosis
-
Dubin M, Stoppani AOM (2000). Muerte celular programada y apoptosis. Medicina 60: 375-386.
-
(2000)
Medicina
, vol.60
, pp. 375-386
-
-
Dubin, M.1
Stoppani, A.O.M.2
-
8
-
-
0027987063
-
Effect of 5-nitroindole on adenylate energy charge, oxidative phosphorylation and lipid peroxidation in rat hepatocytes
-
Dubin M, Carrizo PH, Biscardi AM, Fernandez Villamil SH, Stoppani AOM (1994). Effect of 5-nitroindole on adenylate energy charge, oxidative phosphorylation and lipid peroxidation in rat hepatocytes. Biochem Pharmacol 48: 1483-1492.
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 1483-1492
-
-
Dubin, M.1
Carrizo, P.H.2
Biscardi, A.M.3
Fernandez Villamil, S.H.4
Stoppani, A.O.M.5
-
9
-
-
0035223367
-
Citotoxicidad de la β-lapcichona, una o-naftoquinona con posibles usos terapéuticos
-
Dubin M, Fernández Villamil SH, Stoppani AOM (2001). Citotoxicidad de la β-lapcichona, una o-naftoquinona con posibles usos terapéuticos. Medicina-Buenos Aires 61: 343-350.
-
(2001)
Medicina-Buenos Aires
, vol.61
, pp. 343-350
-
-
Dubin, M.1
Fernández Villamil, S.H.2
Stoppani, A.O.M.3
-
10
-
-
0042505357
-
Possible cytotoxic effects of lipophilic o-naphthoquinones in isolated rat hepatocytes. Protective mechanisms
-
H.E. Nieburgs, Ed. Elsevier Science Inc
-
Dubin M, Fernández Villamil SH, De Witte N, Carrizo P, Molina Portela MP, Stoppani AOM (2002). Possible cytotoxic effects of lipophilic o-naphthoquinones in isolated rat hepatocytes. Protective mechanisms. In: Sixth International Symposium on Predictive Oncology and Intervention Strategies, H.E. Nieburgs, Ed. Elsevier Science Inc, p. 179.
-
(2002)
Sixth International Symposium on Predictive Oncology and Intervention Strategies
, pp. 179
-
-
Dubin, M.1
Fernández Villamil, S.H.2
De Witte, N.3
Carrizo, P.4
Molina Portela, M.P.5
Stoppani, A.O.M.6
-
11
-
-
0028973302
-
An interleukin-1β-converting enzyme-like protease is a common mediator of apoptosis in thymocytes
-
Fearnhead HO, Dinsdale D, Cohen GM (1995). An interleukin-1β -converting enzyme-like protease is a common mediator of apoptosis in thymocytes. FEBS Lett 375: 283-288.
-
(1995)
FEBS Lett
, vol.375
, pp. 283-288
-
-
Fearnhead, H.O.1
Dinsdale, D.2
Cohen, G.M.3
-
12
-
-
1342335877
-
Semiquinone production by lipophilic o-naphthoquinones
-
Fernández Villamil SH, Dubin M, Molina Portela MP, Perissinotti L LJ, Brusa MA, Stoppani AOM (1997). Semiquinone production by lipophilic o-naphthoquinones. Redox Report 3: 245-252.
-
(1997)
Redox Report
, vol.3
, pp. 245-252
-
-
Fernández Villamil, S.H.1
Dubin, M.2
Molina Portela, M.P.3
Perissinotti, L.L.J.4
Brusa, M.A.5
Stoppani, A.O.M.6
-
14
-
-
17544391279
-
Induction of DNA topoisomerase 11-mediated DNA cleavage by β-lapachone and related naphthoquinones
-
Frydman B, Marton LJ, Sun JS, Neder K, Witiak DT, Liu AA, Wang H-M, Mao Y, Wu H-Y, Sanders MM, Liu LF (1997). Induction of DNA topoisomerase 11-mediated DNA cleavage by β-lapachone and related naphthoquinones. Cancer Res 57: 620-627.
-
(1997)
Cancer Res
, vol.57
, pp. 620-627
-
-
Frydman, B.1
Marton, L.J.2
Sun, J.S.3
Neder, K.4
Witiak, D.T.5
Liu, A.A.6
Wang, H.-M.7
Mao, Y.8
Wu, H.-Y.9
Sanders, M.M.10
Liu, L.F.11
-
15
-
-
0021835907
-
Effects of β-lapachone, a peroxide-generating quinone, on macromolecule synthesis and degradation in Trypanosoma cruzi
-
Goijman SG, Stoppani AOM (1985). Effects of β-lapachone, a peroxide-generating quinone, on macromolecule synthesis and degradation in Trypanosoma cruzi. Arch Biochem Biophys 240: 273-280.
-
(1985)
Arch Biochem Biophys
, vol.240
, pp. 273-280
-
-
Goijman, S.G.1
Stoppani, A.O.M.2
-
16
-
-
0033942431
-
The morphology of apoptosis
-
Hacker G (1999). The morphology of apoptosis. Cell Tissue Res 301: 283-288.
-
(1999)
Cell Tissue Res
, vol.301
, pp. 283-288
-
-
Hacker, G.1
-
17
-
-
0033177892
-
Cytoplasmic vacuolation, adaptation and cell death, a view on new perspectives and features
-
Henics T, Wheatley DN (1999). Cytoplasmic vacuolation, adaptation and cell death, a view on new perspectives and features. Bio Cell 91: 485-498.
-
(1999)
Bio Cell
, vol.91
, pp. 485-498
-
-
Henics, T.1
Wheatley, D.N.2
-
18
-
-
0033276625
-
β-lapachone induces cell cycle arrest and apoptosis in human colon cancer cells
-
Huang L, Pardee AB (1999). β-lapachone induces cell cycle arrest and apoptosis in human colon cancer cells. Mol Med 5: 711-720.
-
(1999)
Mol Med
, vol.5
, pp. 711-720
-
-
Huang, L.1
Pardee, A.B.2
-
19
-
-
0032583203
-
SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis
-
Huot J, Houle F, Rousseau S, Deschesness RG, Shah GM, Landry J (1998). SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis. J Cell Biol 143: 1361-1373.
-
(1998)
J Cell Biol
, vol.143
, pp. 1361-1373
-
-
Huot, J.1
Houle, F.2
Rousseau, S.3
Deschesness, R.G.4
Shah, G.M.5
Landry, J.6
-
20
-
-
0021160336
-
A quantitative fluorimetric assay for the determination of oxidant production by polymorphonuclear leukocytes: Its use in the simultaneous fluorimetric assay of celular activation processes
-
Hyslop PA, Sklar LA (1984). A quantitative fluorimetric assay for the determination of oxidant production by polymorphonuclear leukocytes: its use in the simultaneous fluorimetric assay of celular activation processes. Arch Biochem Biophys 141: 380-386.
-
(1984)
Arch Biochem Biophys
, vol.141
, pp. 380-386
-
-
Hyslop, P.A.1
Sklar, L.A.2
-
21
-
-
0030712860
-
ERM (ezrin/radixin/moesin)-baswd molecular mechanism of microvillar breakdown at an early stage of apoptosis
-
Kondo F, Takeuchi K, Doi Y, Yonemura S, Nagata S, Tsukita D (1997). ERM (ezrin/radixin/moesin)-baswd molecular mechanism of microvillar breakdown at an early stage of apoptosis. J Cell Biol 139: 749-758.
-
(1997)
J Cell Biol
, vol.139
, pp. 749-758
-
-
Kondo, F.1
Takeuchi, K.2
Doi, Y.3
Yonemura, S.4
Nagata, S.5
Tsukita, D.6
-
22
-
-
0033288336
-
Mitochondrial control of apoptosis: An overview
-
G.C. Brown, D.G. Nicholls, C.E. Cooper, Eds. Portland Press
-
Kroemer G (1999). Mitochondrial control of apoptosis: an overview. In: Mitochondria and Cell Death, G.C. Brown, D.G. Nicholls, C.E. Cooper, Eds. Portland Press, pp. 1-15.
-
(1999)
Mitochondria and Cell Death
, pp. 1-15
-
-
Kroemer, G.1
-
23
-
-
0029360394
-
Induction of apoptosis byfi-lapachone in human prostate cancer cells
-
Li CJ, Wang C, Pardee AB (1995). Induction of apoptosis byfi-lapachone in human prostate cancer cells. Cancer Res 55: 3712-3715.
-
(1995)
Cancer Res
, vol.55
, pp. 3712-3715
-
-
Li, C.J.1
Wang, C.2
Pardee, A.B.3
-
24
-
-
0034570848
-
Potent induction of apoptosis by β-lapachone in human multiple myeloma cell lines and patient cells
-
Li Y, Li CJ, Yu D, Pardee AB (2000). Potent induction of apoptosis by β-lapachone in human multiple myeloma cell lines and patient cells. Mol Med 6: 1008-1015.
-
(2000)
Mol Med
, vol.6
, pp. 1008-1015
-
-
Li, Y.1
Li, C.J.2
Yu, D.3
Pardee, A.B.4
-
25
-
-
0036040863
-
Effect of the lipophilic o-naphthoquinone CG 10-248 on rat liver mitochondria structure and function
-
López LM, Pellegrino de Iraldi A, Carrizo PH, Dubin M, Stoppani AOM (2002). Effect of the lipophilic o-naphthoquinone CG 10-248 on rat liver mitochondria structure and function Biocell 26: 237-245.
-
(2002)
Biocell
, vol.26
, pp. 237-245
-
-
López, L.M.1
Pellegrino de Iraldi, A.2
Carrizo, P.H.3
Dubin, M.4
Stoppani, A.O.M.5
-
26
-
-
0032965633
-
Suppression of tumor necrosis factor-activated nuclear transcription factorkB, activator protein- 1, c-Jun N-terminal kinase, and apoptosis by β-lapachone
-
Manna S, Gad YP, Mukhopadhyay A, Aggarwal BB (1999). Suppression of tumor necrosis factor-activated nuclear transcription factorkB, activator protein- 1, c-Jun N-terminal kinase, and apoptosis by β-lapachone. Biochem Pharmacol 57: 763-774.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 763-774
-
-
Manna, S.1
Gad, Y.P.2
Mukhopadhyay, A.3
Aggarwal, B.B.4
-
27
-
-
0023694098
-
Menadione-induced blebformation in hepatocytes is associated with the oxidation of thiol groups in actin
-
Mirabelli F, Salis A, Marinoni V, Finardi G, Bellomo G, Thör H, Orrenius DS (1988). Menadione-induced blebformation in hepatocytes is associated with the oxidation of thiol groups in actin. Arch Biochem Biophys 264: 261-269.
-
(1988)
Arch Biochem Biophys
, vol.264
, pp. 261-269
-
-
Mirabelli, F.1
Salis, A.2
Marinoni, V.3
Finardi, G.4
Bellomo, G.5
Thör, H.6
Orrenius, D.S.7
-
31
-
-
0000865129
-
Propiedades electrónicas y actividad redox de naftoquinonas
-
Paulino M, Hansz M, Hikichi N, Tabares G, Molina Portela MP, Fernandez Villamil SH, Sreider CM, Stoppani AOM (1994). Propiedades electrónicas y actividad redox de naftoquinonas. An Asoc Quim Argent 82: 371-389.
-
(1994)
An Asoc Quim Argent
, vol.82
, pp. 371-389
-
-
Paulino, M.1
Hansz, M.2
Hikichi, N.3
Tabares, G.4
Molina Portela, M.P.5
Fernandez Villamil, S.H.6
Sreider, C.M.7
Stoppani, A.O.M.8
-
32
-
-
0034009970
-
NAD(P)H: Quinone oxidoreductase activity is the principal determinant of β-lapachone cytotoxicity
-
Pink JJ, Planchon SM, Tagliarino C, Varnes ME, Siegel D, Boothman DA (2000a). NAD(P)H: Quinone oxidoreductase activity is the principal determinant of β-lapachone cytotoxicity. J Biol Chem 275: 5416-5424.
-
(2000)
J Biol Chem
, vol.275
, pp. 5416-5424
-
-
Pink, J.J.1
Planchon, S.M.2
Tagliarino, C.3
Varnes, M.E.4
Siegel, D.5
Boothman, D.A.6
-
33
-
-
0034653956
-
Activation of a cysteine protease in MCF-7 and T47D breast cancer cells during β-lapachone-mediated apoptosis
-
Pink JJ, Wuerzberger-Davis S, Tagliarino C, Planchon SM, Yang XH, Froelich CJ, Boothman DA (2000b). Activation of a cysteine protease in MCF-7 and T47D breast cancer cells during β-lapachone-mediated apoptosis. Exp Cell Res 255: 144-155.
-
(2000)
Exp Cell Res
, vol.255
, pp. 144-155
-
-
Pink, J.J.1
Wuerzberger-Davis, S.2
Tagliarino, C.3
Planchon, S.M.4
Yang, X.H.5
Froelich, C.J.6
Boothman, D.A.7
-
34
-
-
0028982219
-
β-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: A p53-independent response
-
Planchon SM, Wuerzberger S, Frydman B, Witiak DT, Hutson P, Church DR, Wilding G, Boothman DA (1995).β-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: A p53-independent response. Cancer Res 55: 3706-3711.
-
(1995)
Cancer Res
, vol.55
, pp. 3706-3711
-
-
Planchon, S.M.1
Wuerzberger, S.2
Frydman, B.3
Witiak, D.T.4
Hutson, P.5
Church, D.R.6
Wilding, G.7
Boothman, D.A.8
-
35
-
-
0033129747
-
Bcl-2 protects against β-lapachonemediated caspase 3 activation and apoptosis in human myeloid leukemia (HL-60) cells
-
Planchon SM, Wuerzberger-Davis SM, Pink JJ, Robertson KA, Bornmann WG, Boothman DA (1999). Bcl-2 protects against β-lapachonemediated caspase 3 activation and apoptosis in human myeloid leukemia (HL-60) cells. Oncol Rep 6: 485-492.
-
(1999)
Oncol Rep
, vol.6
, pp. 485-492
-
-
Planchon, S.M.1
Wuerzberger-Davis, S.M.2
Pink, J.J.3
Robertson, K.A.4
Bornmann, W.G.5
Boothman, D.A.6
-
36
-
-
0021229959
-
β-lapachone: Synthesis of derivatives and activities in tumor models
-
Schaffner-Sabba K, Schmidt-Ruppin KH, Wehrli W, Schuerch AR, Wasley JWF (1984). β-lapachone: synthesis of derivatives and activities in tumor models. J Med Chem 27: 990-994.
-
(1984)
J Med Chem
, vol.27
, pp. 990-994
-
-
Schaffner-Sabba, K.1
Schmidt-Ruppin, K.H.2
Wehrli, W.3
Schuerch, A.R.4
Wasley, J.W.F.5
-
37
-
-
0015752890
-
Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion
-
Seglen PO (1973). Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion. Exp Cell Res 82: 391-398.
-
(1973)
Exp Cell Res
, vol.82
, pp. 391-398
-
-
Seglen, P.O.1
-
38
-
-
0033556233
-
2-terminal kinase and subsequent CPP32/Yama during topoisomerase inhibitor β-lapachone-induced apoptosis through an oxidation dependent pathway
-
2-terminal kinase and subsequent CPP32/Yama during topoisomerase inhibitor β-lapachone-induced apoptosis through an oxidation dependent pathway. Cancer Res 59: 391-398.
-
(1999)
Cancer Res
, vol.59
, pp. 391-398
-
-
Shiah, S.-G.1
Chuang, S.-E.2
Chau, Y.-P.3
Shen, S.-C.4
Kuo, M.-L.5
-
39
-
-
0002104051
-
Cytotoxicity of lipophilic o-naphthoquinones: Structure-activity relationship
-
Stoppani AOM, Goijman S, Dubin M, Fernández Villamil SH, Molina Portela MP, Biscardi AM, Paulino M (2000). Cytotoxicity of lipophilic o-naphthoquinones: structure-activity relationship. Trends Comp Biochem Physiol 7: 1-16.
-
(2000)
Trends Comp Biochem Physiol
, vol.7
, pp. 1-16
-
-
Stoppani, A.O.M.1
Goijman, S.2
Dubin, M.3
Fernández Villamil, S.H.4
Molina Portela, M.P.5
Biscardi, A.M.6
Paulino, M.7
-
40
-
-
0023752311
-
Alterations in hepatocyte cytoskeleton caused by redox cycling and alkylating quinones
-
Thör H, Mirabelli F, Salis A, Cohen GM, Bellomo G, Orrenius S (1988). Alterations in hepatocyte cytoskeleton caused by redox cycling and alkylating quinones. Arch Biochem Biophys 266: 397-407.
-
(1988)
Arch Biochem Biophys
, vol.266
, pp. 397-407
-
-
Thör, H.1
Mirabelli, F.2
Salis, A.3
Cohen, G.M.4
Bellomo, G.5
Orrenius, S.6
-
41
-
-
0030613796
-
Bcl-x(L) regulates the membrane potential and volume homeostasis of mitochondria
-
Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB (1997). Bcl-x(L) regulates the membrane potential and volume homeostasis of mitochondria. Cell 91: 627-637.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
42
-
-
0032486082
-
DNA damage and cytotoxicity induced by β-lapachone: Relation to poly(ADP-ribose)polymerase inhibition
-
Vanni A, Fiore M, De Salvia R, Cundari E, Ricordy R, Ceccarelli R, Degrassi F (1998). DNA damage and cytotoxicity induced by β-lapachone: relation to poly(ADP-ribose)polymerase inhibition. Mutat Res 401: 55-63.
-
(1998)
Mutat Res
, vol.401
, pp. 55-63
-
-
Vanni, A.1
Fiore, M.2
De Salvia, R.3
Cundari, E.4
Ricordy, R.5
Ceccarelli, R.6
Degrassi, F.7
-
43
-
-
0026605991
-
Mechanism of DNA damage induced in rat hepatocytes by quinones
-
Walles S (1992). Mechanism of DNA damage induced in rat hepatocytes by quinones. Cancer Res 63: 47-52.
-
(1992)
Cancer Res
, vol.63
, pp. 47-52
-
-
Walles, S.1
-
44
-
-
0032080821
-
Induction of apoptosis in MCF-7: WS8 cancer cells by β-lapachone
-
Wuerzberger SM, Pink JJ, Planchon SM, Byers KL, Bornmann WG, Bothman DA (1998). Induction of apoptosis in MCF-7: WS8 cancer cells by β-lapachone. Cancer Res 58: 1876-1885.
-
(1998)
Cancer Res
, vol.58
, pp. 1876-1885
-
-
Wuerzberger, S.M.1
Pink, J.J.2
Planchon, S.M.3
Byers, K.L.4
Bornmann, W.G.5
Bothman, D.A.6
-
45
-
-
0029101644
-
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
-
Zamzami N, Marchetti P, Castedo M, Decaudin D, Macho A, Hirsch T, Susin SA, Petit PX, Mignotte B, Kroemer G (1995). Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182: 367-377.
-
(1995)
J Exp Med
, vol.182
, pp. 367-377
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
Decaudin, D.4
Macho, A.5
Hirsch, T.6
Susin, S.A.7
Petit, P.X.8
Mignotte, B.9
Kroemer, G.10
-
46
-
-
0029983059
-
Inhibitors ofpermeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
-
Zamzami N, Marchetti P, Castedo M, Hirsch T, Susin SA, Masse B, Kroemer G (1996). Inhibitors ofpermeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Lett 384: 53-57.
-
(1996)
FEBS Lett
, vol.384
, pp. 53-57
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
Hirsch, T.4
Susin, S.A.5
Masse, B.6
Kroemer, G.7
|