Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation

Biochemistry

Volumn 42, Issue 33, 2003, Pages 9959-9969

  Tatham, Michael H ^b   Kim, Suhkmann ^a,d   Yu, Bin ^a   Jaffray, Ellis ^b   Song, Jing ^a   Zheng, Jian ^a   Rodriguez, Manuel S ^c   Hay, Ronald T ^b   Chen, Yuan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

^c INSTITUT JACQUES MONOD   (France)

^d Pusan National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CALORIMETRY; CELLS; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUBSTITUTION REACTIONS; SUBSTRATES; TITRATION;

BIOCHEMICAL ANALYSIS;

ENZYMES;

E2 CONJUGATING ENZYME; ENZYME; PROTEIN; PROTEIN RANGAP1; PROTEIN UBC9; SUMO 1 PROTEIN; SUMO 2 PROTEIN; SUMO 3 PROTEIN; SUMO PROTEIN; UBIQUITIN; UBIQUITIN LIKE PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALORIMETRY; CONJUGATION; CORRELATION ANALYSIS; ENZYME BINDING; MOLECULAR MECHANICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; GLUTATHIONE TRANSFERASE; GTPASE-ACTIVATING PROTEINS; HUMANS; LIGASES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUMO-1 PROTEIN; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINS;

EID: 0041972581     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0345283     Document Type: Article

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