Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum

Journal of Biological Chemistry

Volumn 278, Issue 37, 2003, Pages 34804-34811

  Furman, Margo H ^c   Loureiro, Joana ^c   Ploegh, Hidde L ^a   Tortorella, Domenico ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; BIOLOGICAL MEMBRANES; BIOSYNTHESIS; CYTOLOGY; HISTOLOGY; PROTEINS; REACTION KINETICS;

HEAVY CHAIN CONJUGATES;

BIOCHEMISTRY;

GENE PRODUCT; LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PROTEIN US11; PROTEIN US2; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IN VITRO STUDY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN TARGETING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT;

ANIMALS; CYTOSOL; ENDOPLASMIC RETICULUM; HUMANS; KINETICS; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; PROTEIN BIOSYNTHESIS; PROTEIN FOLDING; PROTEIN TRANSPORT; RABBITS; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; UBIQUITIN; VIRAL ENVELOPE PROTEINS; VIRAL PROTEINS;

CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 5;

EID: 0041816452     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300913200     Document Type: Article

References (38)

1. Ellgaard, L., Molinari, M., and Helenius, A. (1999) Science 286, 1882-1888
2. Brodsky, J. L., and McCracken, A. A. (1999) Semin. Cell Dev. Biol. 10, 507-513
3. Plemper, R. K., and Wolf, D. H. (1999) Trends Biochem. Sci. 24, 266-270
4. Tortorella, D., Gewurz, B. E., Furman, M. H., Schust, D. J., and Ploegh, H. L. (2000) Annu. Rev. Immunol. 18, 861-926
5. Wiertz, E. J., Tortorella, D., Bogyo, M., Yu, J., Mothes, W., Jones, T. R., Rapoport, T. A., and Ploegh, H. L. (1996a) Nature 384, 432-438
6. Wiertz, E. J., Jones, T. R., Sun, L., Bogyo, M., Geuze, H. J., and Ploegh, H. L. (1996b) Cell 84, 769-779
7. Tirosh, B., Furman, M. H., Tortorella, D., and Ploegh, H. L. (2003) J. Biol. Chem. 278, 6664-6672
8. Fiebiger, E., Story, C., Ploegh, H. L., and Tortorella, D. (2002) EMBO J. 21, 1041-1053
9. Pilon, M., Schekman, R., and Romisch, K. (1997) EMBO J. 16, 4540-4548
10. Plemper, R. K., Bohmler, S., Bordallo, J., Sommer, T., and Wolf, D. H. (1997) Nature 388, 891-895
11. Zhou, M., and Schekman, R. (1999) Mol. Cell 4, 925-934
12. Bebok, Z., Mazzochi, C., King, S. A., Hong, J. S., and Sorscher, E. J. (1998) J. Biol. Chem. 273, 29873-29878
13. Wilhovsky, S., Gardner, R., and Hampton, R. (2000) Mol. Biol. Cell 11, 1697-1708
14. Tiwari, S., and Weissman, A. M. (2001) J. Biol. Chem. 276, 16193-16200
15. Jarosch, E., Taxis, C., Volkwein, C., Bordallo, J., Finley, D., Wolf, D. H., and Sommer, T. (2002) Nat. Cell Biol. 4, 134-139
16. Braun, S., Matuschewski, K., Rape, M., Thoms, S., and Jentsch, S. (2002) EMBO J. 21, 615-621
17. Ye, Y., Meyer, H. H., and Rapoport, T. A. (2001) Nature 414, 652-656
18. Shamu, C. E., Story, C. M., Rapoport, T. A., and Ploegh, H. L. (1999) J. Cell Biol. 147, 45-58
19. Shamu, C. E., Flierman, D., Ploegh, H. L., Rapoport, T. A., and Chau, V. (2001) Mol. Biol. Cell 12, 2546-2555
20. Kikkert, M., Hassink, G., Barel, M., Hirsch, C., van der Wal, F. J., and Wiertz, E. (2001) Biochem. J. 358, 369-377
21. Story, C. M., Furman, M. H., and Ploegh, H. L. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 8516-8521
22. Huppa, J. B., and Ploegh, H. L. (1997) J. Exp. Med. 186, 393-403
23. Jones, T. R., Hanson, L. K., Sun, L., Slater, J. S., Stenberg, R. M., and Campbell, A. E. (1995) J. Virol. 69, 4830-4841
24. Neefjes, J. J., and Ploegh, H. L. (1988) Eur. J. Immunol. 18, 801-810
25. Parham, P., Barnstable, C. J., and Bodmer, W. F. (1979) J. Immunol. 123, 342-349
26. Furman, M. H., Ploegh, H. L., and Tortorella, D. (2002) J. Biol. Chem. 277, 3258-3267
27. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, p. 311, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
28. Bogyo, M., McMaster, J. S., Gaczynska, M., Tortorella, D., Goldberg, A. L., and Ploegh, H. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 6629-6634
29. Chong, S., Mersha, F. B., Comb, D. G., Scott, M. E., Landry, D., Vence, L. M., Perler, F. B., Benner, J., Kucera, R. B., Hirvonen, C. A., Pelletier, J. J., Paulus, H., and Xu, M. Q. (1997) Gene (Amst.) 192, 271-281
30. Borodovsky, A., Ovaa, H., Kolli, N., Gan-Erdene, T., Wilkinson, K. D., Ploegh, H. L., and Kessler, B. M. (2002) Chem. Biol. 9, 1149-1159
31. Ploegh, H. L. (1995) in Current Protocols in Protein Science (Coligan, J. E., Dunn, B. M., Ploegh, H. L., Speicher, D. W., and Wingfield, P. T., eds.) pp. 10.0.1-10.1.34, John Wiley & Sons, Inc., New York
32. Huppa, J. B., and Ploegh, H. L. (1997) Immunity 7, 113-122
33. Tortorella, D., Story, C. M., Huppa, J. B., Wiertz, E. J., Jones, T. R., Bacik, I., Bennink, J. R., Yewdell, J. W., and Ploegh, H. L. (1998) J. Cell Biol. 142, 365-376
34. Margottin, F., Bour, S. P., Durand, H., Selig, L., Benichou, S., Richard, V., Thomas, D., Strebel, K., and Benarous, R. (1998) Mol. Cell 1, 565-574
35. Boname, J. M., and Stevenson, P. G. (2001) Immunity 15, 627-636
36. Gewurz, B. E., Wang, E. W., Tortorella, D., Schust, D. J., and Ploegh, H. L. (2001) J. Virol. 75, 5197-5204
37. Gewurz, B. E., Gaudet, R., Tortorella, D., Wang, E. W., Ploegh, H. L., and Wiley, D. C. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 6794-6799
38. Pickart, C. M. (2001) Mol. Cell 8, 499-504