A comparison of topiramate and acetazolamide on seizure duration and paired-pulse inhibition in the dentate gyrus of the rat

Epilepsy Research

Volumn 40, Issue 2-3, 2000, Pages 147-153

  Stringer, Janet L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Acetazolamide; Dentate gyrus; Inhibition; Long term Potentiation; Seizures; Topiramate

Indexed keywords

ACETAZOLAMIDE; ANTICONVULSIVE AGENT; CARBONATE DEHYDRATASE; TOPIRAMATE;

AFTERDISCHARGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFECT; ELECTROENCEPHALOGRAM; LONG TERM POTENTIATION; MALE; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; SEIZURE THRESHOLD;

ACETAZOLAMIDE; ANIMALS; ANTICONVULSANTS; DENTATE GYRUS; DRUG EVALUATION, PRECLINICAL; FRUCTOSE; LONG-TERM POTENTIATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES;

EID: 0034039327     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(00)00118-2     Document Type: Article

References (25)

1. Amano K., Hamada K., Yagi K., Seino M. Antiepileptic effects of topiramate on amygdaloid kindling in rats. Epilepsy Res. 31:1998;123-128.
2. Bialer M., Johannessen S.l., Kupferburg H.J., Levy R.H., Loiseau P., Perucca E. Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference (EILAT IV). Epilepsy Res. 34:1999;1-41.
3. Edmonds H.L., Jiang Y.D., Zhang P.Y., Shank R.P. Anticonvulsant activity of topiramate and phenytoin in a rat model of ischemia-induced epilepsy. Life Sci. 59:1996;PL127-PL137.
4. Joy R.M., Albertson T.E. Convulsant-induced changes in perforant pathdentate gyrus excitability in urethane anesthetized rats. J. Pharmacol. Exp. Ther. 246:1988;887-895.
5. Kapur J., Stringer J.L., Lothman E.W. Evidence that repetitive seizures in the hippocampus cause a lasting reduction of GABAergic inhibition. J. Neurophysiol. 61:1989;417-426.
6. Ransom B.R., Orkand R.X. Glial-neuronal interactions in non-synaptic areas of the brain: studies in the optic nerve. Trends Neurosci. 19:1996;352-358.
7. Reife R.A. Topiramate. Shorvon S., Dreifuss F., Fish D., Thomas D. The Treatment of Epilepsy. 1996;471-481 Blackwell Science, Oxford, UK.
8. Resor S.R., Resor L.D., Woodbury D.M., Kemp J.W. Acetazolamide. Levy R.H., Mattson R.H., Meldrum B.S. Antiepileptic Drugs. 1995;969-985 Raven Press, New York.
9. Rock D.M., Taylor C.P. Effects of diazepam, pentobarbital, phenytoin and pentylenetetrazol on hippocampal paired-pulse inhibition in vivo. Neurosci. Lett. 65:1986;265-270.
10. Sapirstein V.S., Strocchi P., Gilbert J.M. Properties and function of brain carbonic anhydrase. Tashian R.E., Hewitt-Emmett D. Biology and Chemistry of the Carbonic Anhydrases. 1984;481-493 Ann. NY Acad. Sci. New York.
11. Shank R.P., Gardocki J.F., Vaught J.L. Topiramate: preclinical evaluation of a structurally novel anticonvulsant. Epilepsia. 35:1994;450-460.
12. Shank, R.P., Gardocki, J. F, Streeter, A.J., Maryanoff, B.E., 2000. An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics and mechanism of action, Epilepsia. 41, 53-59.
13. Simeone T.A., McClellan A.M.L., Wilcox K.S., Twyman R.E., White H.S. Topiramate potentiates the recombinant a2β2y2S GABAA receptor mediated chloride current. Soc. Neurosci. Abstr. 25:1999;1223.
14. Stringer J.L., Lothman E.W. Repetitive seizures cause an increase in paired-pulse inhibition in the dentate gyrus. Neurosci. Lett. 105:1989;91-95.
15. Stringer J.L., Lothman E.W. Maximal dentate activation: characteristics and alterations after repeated seizures. J. Neurophysiol. 62:1989;136-143.
16. Stringer J.L., Lothman E.W. Maximal dentate activation: a tool to screen compounds for activity against limbic seizures. Epilepsy Res. 5:1990;169-176.
17. Stringer J.L., Lothman E.W. Use of maximal dentate activation to study the effect of drugs on kindling and kindled responses. Epilepsy Res. 6:1990;180-186.
18. Stringer J.L., Lothman E.K. Reverberatory seizure discharges in hippocampal-parahippocampal circuits. Neurology. 116:1992;198-203.
19. Stringer, J.L. Taylor, C.P. The effects of gabapentin in the rat hippocampus are mimicked by two structural analogs, but not by nimodipine. submitted.
20. Stringer J.L. Rapid kindling: behavioral and electrographic. Peterson S.L., Albertson T.E. Neuropharmacology Methods in Epilepsy Research. 1998;75-94 CIRC Press, New York.
21. Wauquier A., Zhou S. Topiramate: a potent anticonvulsant in the amygdala-kindled rat. Epilepsy Res. 24:1996;73-77.
22. White H.S., Brown S.D., Woodhead J.H., Skeen G.A., Wolf H.H. Topiramate enhances GABA-mediated chloride flux and GABA-evoked currents in mouse brain neurons and increases seizure threshold. Epilepsy Res. 28:1997;167-179.
23. White, H.S., Woodhead, J., Wolf, H.H., 2000. Topiramate enhances GABA-evoked currents in mouse cortical neurons and elevates seizure threshold through a non-benzodiazepine receptor mechanism, Epilepsia. 41, 517-520.
24. Xiong Z.-Q., Stringer J.L. Effects of felbamate, gabapentin and lamotrigine on seizure parameters and excitability in the rat hippocampus. Epilepsy Res. 27:1997;187-194.
25. Zhang, X.L., Velumian, A., Jones, O.T., Carlen, P.L., 2000. Modulation of high voltage-activated calcium channels in dentate granule cells by topiramate. Epilepsia. 41, 552-560.