Inhibition of mouse and human CYP 1A- and 2E1-dependent substrate metabolism by the isoflavonoids genistein and equol

Food and Chemical Toxicology

Volumn 36, Issue 5, 1998, Pages 375-382

  Helsby, N A ^a   Chipman, J K ^a   Gescher, A ^b   Kerr, D ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Cytochrome P 450; Equol; Genistein; Isoflavonoids

Indexed keywords

ALPHA NAPHTHOFLAVONE; CYTOCHROME P450 INHIBITOR; CYTOCHROME P450 ISOENZYME; DIETHYLTHIOCARBAMATE; DIMETHYLBENZ[A]ANTHRACENE; EQUOL; ETHOXYRESORUFIN; GENISTEIN; ISOFLAVONOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PREVENTION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DIET; ENZYME INHIBITION; FEMALE; GENOTOXICITY; LIVER MICROSOME METABOLISM; MALE; MOUSE; NONHUMAN; RAT; XENOBIOTIC METABOLISM;

ANIMALS; CELL LINE, TRANSFORMED; CHROMANS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; GENISTEIN; HUMANS; ISOFLAVONES; MALE; MICE; MICE, INBRED BALB C; MICROSOMES, LIVER; MONOAMINE OXIDASE INHIBITORS; NITROPHENOLS; OXAZINES; RATS; RATS, WISTAR; SUBSTRATE SPECIFICITY;

EID: 0031835035     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(97)00171-3     Document Type: Article

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