Effect of intact and isoflavone-depleted soy protein on NMU-induced rat mammary tumorigenesis

Carcinogenesis

Volumn 21, Issue 5, 2000, Pages 929-935

  Cohen, L A ^a   Zhao, Z ^a   Pittman, B ^a   Scimeca, J A ^b  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b Kraft Foods Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN; ISOFLAVONE; METHYLNITROSOUREA; SOYBEAN PROTEIN; SUPRO 670HG; SUPRO 670IF;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; CANCER INCIDENCE; CANCER PREVENTION; CHEMICAL CARCINOGENESIS; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DIET; FEMALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0034075877     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/21.5.929     Document Type: Article

References (48)

1. Fournier, D.B., Erdman, J.W. and Gordon, G.B. (1998) Soy, its components and cancer prevention: a review of the in vitro, animal and human data. Cancer Epidemiol. Biomarkers Prev., 7, 1055-1065.
2. Adlercreutz, C.H.T., Goldin, B.R., Gorbach, S.L., Höckerstedt, K.A., Watanabe, S., Hämäläinen, E.K., Markkanen, M.H., Mäkelä, T.H., Wähälä, K.T, Hase, T.A. and Fotsis, T. (1995) Soybean phytoestrogen intake and cancer risk. J. Nutr., 125, 757S-770S.
3. Adlercreutz, H. (1998) Evolution nutrition, intestinal microflora and prevention of cancer: a hypothesis. Proc. Soc. Exp. Biol. Med., 217, 241-246.
4. Barnes, S., Peterson, G., Grubbs, C. and Setchell, K. (1998) Potential role of dietary isoflavones in the prevention of cancer. Adv. Exp. Med. Biol., 354, 135-147.
5. Barnes, S. (1995) Effect of genistein on in vitro and in vivo models of cancer. J. Nutr., 125, 777S-783S.
6. Messina, M.J., Persky, V., Setchell, K.D. and Barnes, S. (1994) Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr. Cancer, 21, 113-131.
7. Connolly, J.M., Liu, X.-H. and Rose, D.P. (1997) Effects of dietary menhaden oil, soy and a cyclooxygenase inhibitor on human breast cancer cell growth and metastasis in nude mice. Nutr. Cancer, 29, 48-54.
8. Hawrylewicz, E.J., Zapata, J.J. and Blair, W. (1995) Soy and experimental cancer: animal studies. J. Nutr., 125, 698S-708S.
9. Troll, W., Weisner, R., Shellabarger, C.J., Holtzman, S. and Stone, J.P. (1980) Soybean diet lowers breast tumor incidence in irradiated rats. Carcinogenesis, 1, 469-412.
10. Shamsuddin, A.U. (1995) Inositol phosphates have novel anticancer function. J. Nutr., 123, 725S-732S.
11. Barnes, S., Peterson, G.T. and Coward, L. (1995) Rationale for the use of genistein-containing matrices in chemoprevention trials for breast and prostate cancer. J. Cell Biochem., 22 (suppl.), 181-187.
12. Zava, D.T. and Duwe, G. (1997) Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro. Nutr. Cancer, 27, 31-40.
13. Akiyama, T., Ishida, J., Nakagawa, S., Ogawara, H., Watanabe, S., Itoh, N., Shibuya, M. and Fakanu, Y. (1987) Genistein a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem., 262, 5592-5595.
14. Okura, A., Arakawa, H., Oha, H., Yoshmari, T. and Monden, Y. (1988) Effect of genistein on topoisomerase activity and on the growth of [Val 12] Haras-transformed NIH 3T3 cells. Biochem. Biophys. Res. Commun., 157, 183-189.
15. McCabe, M.J. and Orrenius, S. (1993) Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II. Biochem. Biophys. Res. Commun., 194, 944-950.
16. Fotsis, T., Pepper, M., Adlercreutz, H., Fleischmann, G., Hase, T., Montesano, R. and Schweigerer, L. (1993) Genistein a dietary-derived inhibitor of in vitro angiogenesis. Proc. Natl Acad. Sci. USA, 90, 2690-2694.
17. Kiguchi, K., Constantinou, A.I. and Huberman, E. (1990) Genistein-induced cell differentiation and protein-linked DNA strand breakage in human melanoma cells. Cancer Commun., 2, 271-278.
18. Constantinou, A. and Huberman, E. (1995) Genistein as an inducer of tumor cell differentiation: possible mechanisms of action. Proc. Soc. Exp. Biol. Med., 208, 109-115.
19. Yuan, J.-M., Wang, Q.-S., Ross, K.K., Henderson, B.E. and Yu, M.C. (1995) Diet and breast cancer in Shanghai and Tianjin, China. Br. J. Cancer, 71, 1353-1358.
20. Petrakis, N.L., Barnes, S., King, E.B., Lowenstein, J., Wiencke, J., Lee, M.M., Miike, R., Kirk, M. and Coward, L. (1996) Stimulatory influence of soy protein isolate on breast fluid secretion in pre- and postmenopausal women. Cancer Epidemiol. Biomarkers Prev., 5, 785-794.
21. Barnes, S., Grubbs, C., Setchele, K. and Carlson, J. (1990) Soybeans inhibit mammary tumors in models of breast cancer. In Pariza, M. (ed.) Mutagens and Carcinogens in the Diet. Wiley-Liss, New York, NY, pp. 239-253.
22. Chan, P.C., Head, J.F., Cohen, L.A. and Wynder, E.L. (1977) Influence of dietary fat on the induction of mammary tumors by N-nitrosomethylurea: associated hormone changes and differences between Sprague-Dawley and F344 rats. J. Natl Cancer Inst., 59, 279-283.
23. Reeves, P.G., Neilsen, F.H. and Fahey, G.L.Jr (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr., 123, 1939-1951.
24. Young, S. and Hallowes, R.C. (1973) Tumors of the mammary gland. In Turosov, V.S. (ed.) Pathology of Tumors in Laboratory Animals. IARC, Lyon, Vol. 1, pp. 31-74.
25. Russo, J., Russo, J.H., Rogers, A.E., Van Zwietan, M.J. and Gusterson, B. (1990) Tumours of the Mammary Gland. IARC Scientific Publications no. 99. IARC, Lyon, pp. 47-78.
26. Kaplan, E.L. and Meier, P. (1978) Nonparametric estimation from incomplete observation. J. Am. Statist. Assoc., 53, 457-481.
27. Peto, R. and Peto, J. (1972) A symptomatically efficient rank invariant procedure. J. R. Statist. Soc., 135A, 185-207.
28. Helwig, J.T. and Council, K.A. (eds) (1985) Statistical Analysis User's Guide: Statistics Version, 5th Edn. SAS Institute, Raleigh, NC.
29. Armitage, P. (1966) The chi-square test for heterogeneity of proportions after adjustment for stratification. J. R. Statist. Soc., 28B, 150-163.
30. Fleiss, J.L. (1981) Statistical Methods for Rates and Proportions, 2nd Edn. Wiley, New York, NY, pp. 145-146.
31. Mantel, N. and Haenszel, W. (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl Cancer Inst., 22, 719-748.
32. SAS Institute (1981) SAS for Linear Models: A Guide to the ANOVA and GLM Procedures. SAS Institute, Raleigh, NC.
33. Fleiss, J.L. (1986) The Design and Analysis of Clinical Experiments. Wiley, New York, NY, pp. 220-240.
34. Franke, A.A., Coster, L.J., Cerna, C.M. and Narala, K.K. (1994) Quantitation of phytoestrogens in legumes by HPLC. J. Agric. Food Chem., 42, 1905-1913.
35. Franke, A.A., Guster, L.J., Wang, W. and Shi, C.Y. (1998) HPLC analysis of isoflavonoids and other phenolic agents from foods and from human fluids. Proc. Soc. Exp. Biol. Med., 217, 263-273.
36. Carroll, K.K. (1975) Experimental evidence of dietary factors and hormone dependent cancers. Cancer Res., 35, 3374-3383.
37. Hsueh, A.R., Shipley, R. and Park, H.A. (1992) Quality of dietary protein during initiation and promotion of chemical carcinogenesis in rats. In Ligra, G.U., Beitz, D.C., Beynia, A.C. and Gorman, M.A. (eds) Dietary Proteins: How They Alleviate Disease and Promote Better Health. American Oil Chemists Society, Champaign, IL, pp. 151-162.
38. Appelt, L.C. and Reicks, M.M. (1999) Soy induces phase II enzymes but does not inhibit dimethylbenz(a)anthracene-induced carcinogenesis in female rats. J. Nutr., 129, 1820-1826.
39. Gridley, D.S., Kettering, J.D., Slater, J.M. and Nutter, R.L. (1983) Modification of spontaneous mammary tumors in mice fed different sources of protein, fat, carbohydrate. Cancer Lett., 19, 133-146.
40. Baggott, J.E., Ha, T., Vaughn, W.H., Juliana, M.M., Hardin, J.M. and Grubbs, C. (1990) Effect of Miso (Japanese Soybean Paste) and NaCl on DMBA-induced rat mammary tumors. Nutr. Cancer, 14, 103-109.
41. Gotoh, T., Yamada, K., Yin, H., Ito, A., Kataoka, T. and Dehi, K. (1998) Chemoprevention of N-nitroso-N-methylurea-induced rat mammary carcinogenesis by soy foods or biochanin. Jpn. J. Cancer Res., 89, 137-142.
42. Ito, A., Gato, T., Okamoto, T., Yamada, K. and Roy, G.A. (1996) A combined effect of tamoxifen (TAM) and Miso for the development of mammary tumors induced with NMU in SD rats. Proc. Am. Assoc. Cancer Res., 37, 271.
43. Scholar, E.M. and Toews, M.L. (1994) Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein. Cancer Lett., 87, 159-169.
44. Barnes, S. (1997) The chemopreventive properties of soy isoflavonoids in animal models of breast cancer. Breast Cancer Res. Treat., 46, 169-179.
45. Constantinou, A.I., Mehta, R.G. and Vaughan, A. (1996) Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones. Anticancer Res., 16, 3293-3298.
46. LaMartiniere, C.A., Moore, J.B., Brown, N.M., Thompson, R., Hardin, M.J. and Barnes, S (1995) Genistein suppresses mammary cancer in rats. Carcinogenesis, 16, 2833-2840.
47. La Martiniere, C.A., Murrell, W.B., Manzolillo, P.A., Zhang, J.-X, Barnes, S., Zhang, X., Wei, H. and Brown, N. (1998) Genistein alters the ontogeny of mammary gland development and protects against chemically-induced mammary cancer in rats. Proc. Soc. Exp. Biol. Med., 217, 358-364.
48. Lu, L.-J., Lin, S.N., Grady, J., Nagamani, M. and Anderson, K.E. (1996) Altered kinetics and extent of urinary daidzein and genistein excretion in women during chronic soya exposure. Nutr Cancer, 26, 289-302.