The cyclin D1 alternative transcripts [a] and [b] are expressed in normal and malignant lymphocytes and their relative levels are influenced by the polymorphism at codon 241

Haematologica

Volumn 86, Issue 6, 2001, Pages 563-569

  Howe, D ^a   Lynas, C ^a  

^a MUSGROVE PARK HOSPITAL   (United Kingdom)

Author keywords

Alternative transcripts; Cyclin D1; Lymphocytes; Mantle cell lymphoma; Polymorphism

Indexed keywords

CYCLIN D1;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CORRELATION FUNCTION; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MANTLE CELL LYMPHOMA; PROGNOSIS; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; ALTERNATIVE SPLICING; CASE-CONTROL STUDIES; CYCLIN D1; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC; LYMPHOCYTES; LYMPHOMA, MANTLE-CELL; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SURVIVAL ANALYSIS;

EID: 0034949805     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. The D-cyclins, their kinases and their inhibitors
2. Function of a human cyclin gene as an oncogene
3. Cyclin D1 in breast cancer
4. Cyclin D1 as a cellular proto-oncogene
5. Aberrations of the G1- and G1/S-regulating genes in human cancer
6. Alternate splicing produces a novel cyclin D1 transcript
7. Absence of cyclin D1/PRAD1 point mutations in human breast cancers and parathyroid adenomas and identification of a new cyclin D1 gene polymorphism
8. Cyclin D1/PRAD1/BCL-1 alternative transcript [B] protein product in B-lymphoid malignancies with t(11;14)(q13;q32) translocation
9. Alternatively spliced forms of cyctin D1 modulate entry into cell cycle in an inverse manner
10. Cyclin D1 (PRAD1) alternative transcript b: Full-length cDNA cloning and expression in breast cancers
11. Detection of cyclin D1 (bcl-1, PRAD1) overexpression by a simple competitive reverse transcription-polymerase chain reaction assay in t(11;14)(q13;q32)-bearing B-cell malignancies and/or mantle cell lymphoma
12. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
13. Cyclin D1 protein expression and gene polymorphism in colorectal cancer
14. A multi-agent system simulating human splice site recognition
15. The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences
16. Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck
17. Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer