The Cdk inhibitor p21 is required for necrosis, but it inhibits apoptosis following toxin-induced liver injury

Journal of Biological Chemistry

Volumn 278, Issue 32, 2003, Pages 30348-30355

  Kwon, Young Hye ^b   Jovanovic, Aleksandra ^b   Serfas, Michael S ^b   Tyner, Angela L ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROMES;

CARBON TETRACHLORIDE; CYTOLOGY; GENES;

PROTEINS;

CARBON TETRACHLORIDE; CYCLIN A; CYCLIN DEPENDENT KINASE INHIBITOR; CYTOCHROME P450 2E1; PROTEIN P21; PROTEIN P27; RETINOBLASTOMA PROTEIN; TOXIN;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; LIVER CELL; LIVER INJURY; LIVER NECROSIS; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; WILD TYPE;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; CARBON TETRACHLORIDE; CASPASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; CYTOCHROME P-450 CYP2E1; FEMALE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENOTYPE; HEPATOCYTES; IMMUNOBLOTTING; IN SITU NICK-END LABELING; LIVER; MALE; MICE; MICE, TRANSGENIC; NECROSIS; PHOSPHORYLATION; PRECIPITIN TESTS; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 0041528505     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300996200     Document Type: Article

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