The p21Cip1 protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers

Hepatology

Volumn 35, Issue 5, 2002, Pages 1063-1071

  Jaime, Maribel ^a,b   Pujol, Maria Jessüs ^a   Serratosa, Joan ^b   Pantoja, Cristina ^c   Canela, Nüria ^a   Casanovas, Oriol ^a   Serrano, Manuel ^c   Agell, Neus ^a   Bachs, Oriol ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CDC25A PROTEIN; CYCLIN DEPENDENT KINASE 2; CYCLIN E; DNA; MESSENGER RNA; PHOSPHATASE; PROTEIN P21; PROTEIN P27; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CELLULAR DISTRIBUTION; DNA REPLICATION; DNA SYNTHESIS; LIVER REGENERATION; LIVER RESECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TISSUE REGENERATION;

EID: 0036237044     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.32678     Document Type: Article

References (39)

1. Cyclin-dependent kinases: Engines, clocks, and microprocessors
2. G1 phase progression: Cycling on cue
3. Cyclins and cyclin-dependent kinases: A biochemical view
4. The retinoblastoma protein and cell cycle control
5. Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases
6. Cell cycle-dependent phosphorylation of the retinoblastoma-related protein p130
7. DP E2F proteins: Coordinating transcription with cell cycle progression
8. Regulation of cell proliferation by the E2F transcription factors
9. The Rb/E2F pathway: Expanding roles and emerging paradigms
10. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
11. Cyclin/Cdk-dependent initiation of DNA replication in a human cell-free system
12. Inhibitors of mammalian G1 cyclin-dependent kinases
13. New functional activities for the p21 family of CDK inhibitors
14. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
15. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
16. Control of E2F activity by p21Waf1/Cip1
17. The protein SET regulates the inhibitory effect of p21(Cip1) on cyclin E-cyclin-dependent kinase 2 activity
18. Calmodulin binds to p21 (Cip1) and is involved in the regulation of its nuclear localization
19. p21 (WAF1/Cip1): More than a break to the cell cycle?
20. TOK-1, a novel p21cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase
21. Identification of CIP-1-associated regulator of cyclin B (CARB), a novel p21-binding protein acting in the G2 phase of the cell cycle
22. Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver
23. KIP1 with cyclin ECDK2 during rat liver regeneration
24. Radiation-induced cell cycle arrest compromised by p21 deficiency
25. Experimental pathology of the liver: Restoration of liver of the white rat following partial surgical removal
26. Role of the INK4a locus in tumor suppression and cell mortality
27. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
28. Endogenous thymic factors regulating cell proliferation and analysis of their mechanism of action
29. Alterations in the phosphorylation and activity of DNA polymerase alpha correlate with the change in replicative DNA synthesis as quiescent cells re-enter the cell cycle
30. Phosphorylation of rat liver heterogeneous nuclear ribonucleoproteins A2 and C can be modulated by calmodulin
31. Regulation of cyclin D1, DNA topoisomerase I, and proliferating cell nuclear antigen promoters during the cell cycle
32. Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site
33. Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases
34. A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2
35. p21CIP1 and Cdc25A: Competition between an inhibitor and an activator of cyclin-dependent kinases
36. Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1
37. Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases
38. CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase
39. Calmodulin is essential for cyclin-dependent kinase 4 (Cdk4) activity and nuclear accumulation of cyclin D1-Cdk4 during G1