Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3

Biochemical Journal

Volumn 368, Issue 2, 2002, Pages 597-603

  Brand, Martin D ^a   Pamplona, Reinald ^b   Portero Otín, Manuel ^b   Requena, Jesús R ^c,e   Roebuck, Stephen J ^a   Buckingham, Julie A ^a   Clapham, John C ^d,f   Cadenas, Susana ^a,g  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF LLEIDA   (Spain)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d GLAXOSMITHKLINE   (United Kingdom)

^e UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^f ASTRAZENECA R AND D   (Sweden)

^g INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

Author keywords

Peroxidation; Protein oxidation; Proton leak; Reactive oxygen species; Superoxide

Indexed keywords

AMINO ACIDS; CELLS; FATTY ACIDS; MUSCLE; OXIDATION; PHOSPHOLIPIDS;

BASAL PROTON CONDUCTANCE;

PROTEINS;

6 N CARBOXYETHYLLYSINE; 6 N CARBOXYMETHYLLYSINE; 6 N MALONDIALDEHYDE LYSINE; AMINOADIPIC ACID; FATTY ACID; GLUTAMIC ACID; LYSINE DERIVATIVE; PHOSPHOLIPID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; IN VIVO STUDY; LIPID COMPOSITION; MOUSE; MUSCLE MITOCHONDRION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; SKELETAL MUSCLE;

ANIMALS; BIOLOGICAL MARKERS; CARRIER PROTEINS; FATTY ACIDS; ION CHANNELS; LYSINE; MICE; MICE, MUTANT STRAINS; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; OXIDATIVE STRESS; PHOSPHOLIPIDS; PROTEINS; REACTIVE OXYGEN SPECIES;

ANIMALIA;

EID: 2242425423     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021077     Document Type: Article

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