DHH1 regulates the G1/S-checkpoint following DNA damage or BRCA1 expression in yeast

Journal of Surgical Research

Volumn 113, Issue 1, 2003, Pages 62-73

  Westmoreland, T J ^a   Olson Jr , J A ^a   Saito, W Y ^a   Huper, G ^a   Marks, J R ^a   Bennett, C B ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

BRCA1; DDX6; DHH1; G1 checkpoint; Ionizing radiation; Yeast

Indexed keywords

GALACTOSE; PLASMID DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DHH1; UNCLASSIFIED DRUG;

CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL VIABILITY; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA SCREENING; DNA TRANSCRIPTION; DOWN REGULATION; GENE DELETION; GENE EXPRESSION; HETEROLOGOUS EXPRESSION; IONIZING RADIATION; NONHUMAN; ONCOGENE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; REPORTER GENE; STRAIN DIFFERENCE; TUMOR SUPPRESSOR GENE; WILD TYPE; YEAST;

EID: 0041441252     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-4804(03)00155-0     Document Type: Conference Paper

References (50)

1. Maekawa H., Nakagawa T., Uno Y., Kitamura K., Shimoda C. The ste13+ gene encoding a putative RNA helicase is essential for nitrogen starvation-induced G1 arrest and initiation of sexual development in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 244:1994;456.
2. Hata H., Mitsui H., Liu H., Bai Y., Denis C.L., Shimizu Y., Sakai A. Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae. Genetics. 148:1998;571.
3. Fischer N., Weis K. The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1. Embo J. 21:2002;2788.
4. Tucker M., Valencia-Sanchez M.A., Staples R.R., Chen J., Denis C.L., Parker R. The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell. 104:2001;377.
5. Maillet L., Collart M.A. Interaction between Not1p, a component of the Ccr4-not complex, a global regulator of transcription, and Dhh1p, a putative RNA helicase. J. Biol. Chem. 277:2002;2835.
6. Claus E.B., Risch N., Thompson W.D. Genetic analysis of breast cancer in the cancer and steroid hormone study. Am. J. Hum. Genet. 48:1991;232.
7. Thompson L.H., Schild D. Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat Res. 477:2001;131.
8. Chen Y., Lee W.H., Chew H.K. Emerging roles of BRCA1 in transcriptional regulation and DNA repair. J. Cell. Physiol. 181:1999;385.
9. Zhong Q., et al. Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response. Science. 285:1999;747.
10. Cantor S.B., et al. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell. 105:2001;149.
11. Schlegel B.P., Starita L.M., Parvin J.D. Overexpression of a protein fragment of RNA helicase A causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells. Oncogene. 22:2003;983.
12. Wu L.C., et al. Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat. Genet. 14:1996;430.
13. Deng C.X., Brodie S.G. Roles of BRCA1 and its interacting proteins. Bioessays. 22:2000;728.
14. Wang Y., Cortez D., Yazdi P., Neff N., Elledge S.J., Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes. Dev. 14:2000;927.
15. Wang H., Zeng Z.C., Bui T.A., DiBiase S.J., Qin W., Xia F., Powell S.N., Iliakis G. Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2. Cancer Res. 61:2001;270.
16. Moynahan M.E., Chiu J.W., Koller B.H., Jasin M. Brca1 controls homology-directed DNA repair. Mol. Cell. 4:1999;511.
17. Davies A.A., Masson J.Y., McIlwraith M.J., Stasiak A.Z., Stasiak A., Venkitaraman A.R., West S.C. Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol. Cell. 7:2001;273.
18. Moynahan M.E., Cui T.Y., Jasin M. Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a brca1 mutation. Cancer Res. 61:2001;4842.
19. Scully R., Chen J., Plug A., Xiao Y., Weaver D., Feunteun J., Ashley T., Livingston D.M. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell. 88:1997;265.
20. Lu M., Arrick B.A. Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells evidence for both common and distinct activities of wildtype and mutant forms. Oncogene. 19:2000;6351.
21. Jin S., Zhao H., Fan F., Blanck P., Fan W., Colchagie A.B., Fornace A.J. Jr, Zhan Q. BRCA1 activation of the GADD45 promoter. Oncogene. 19:2000;4050.
22. Fan S., et al. BRCA1 as a potential human prostate tumor suppressor modulation of proliferation, damage responses and expression of cell regulatory proteins. Oncogene. 16:1998;3069.
23. Chen J. Ataxia telangiectasia-related protein is involved in the phosphorylation of BRCA1 following deoxyribonucleic acid damage. Cancer Res. 60:2000;5037.
24. Lee J.S., Collins K.M., Brown A.L., Lee C.H., Chung J.H. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature. 404:2000;201.
25. Bennett C.B., Snipe J.R., Westmoreland J.W., Resnick M.A. SIR functions are required for the toleration of an unrepaired double-strand break in a dispensable yeast chromosome. Mol. Cell. Biol. 21:2001;5359.
26. Bennett C.B., Lewis L.K., Karthikeyan G., Lobachev K.S., Jin Y.H., Sterling J.F., Snipe J.R., Resnick M.A. Genes required for ionizing radiation resistance in yeast. Nat. Genet. 29:2001;426.
27. Kishida M., Tokunaga M., Katayose Y., Yajima H., Kawamura-Watabe A., Hishinuma F. Isolation and genetic characterization of pGKL killer-insensitive mutants (iki) from Saccharomyces cerevisiae. Biosci. Biotechnol. Biochem. 60:1996;798.
28. Akao Y., Marukawa O., Morikawa H., Nakao K., Kamei M., Hachiya T., Tsujimoto Y. The rck/p54 candidate proto-oncogene product is a 54-kilodalton D-E-A-D box protein differentially expressed in human and mouse tissues. Cancer Res. 55:1995;3444.
29. Nakamura A., Amikura R., Hanyu K., Kobayashi S. Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis. Development. 128:2001;3233.
30. Navarro R.E., Shim E.Y., Kohara Y., Singson A., Blackwell T.K. cgh-1, a conserved predicted RNA helicase required for gametogenesis and protection from physiological germline apoptosis in C. elegans. Development. 128:2001;3221.
31. Weinert T.A., Hartwell L.H. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science. 241:1988;317.
32. Mendenhall M.D., Hodge A.E. Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 62:1998;1191.
33. Zhang J., Schneider C., Ottmers L., Rodriguez R., Day A., Markwardt J., Schneider B.L. Genomic Scale Mutant Hunt Identifies Cell Size Homeostasis Genes in S. cerevisiae. Curr. Biol. 12:2002;1992.
34. Akao Y., Matsuda Y. Identification and chromosome mapping of the mouse homologue of the human gene (DDX6) that encodes a putative RNA helicase of the DEAD box protein family. Cytogenet. Cell. Genet. 75:1996;38.
35. Humphrey J.S., Salim A., Erdos M.R., Collins F.S., Brody L.C., Klausner R.D. Human BRCA1 inhibits growth in yeast potential use in diagnostic testing. Proc. Natl. Acad. Sci. USA. 94:1997;5820.
36. Holt J.T., Thompson M.E., Szabo C., Robinson-Benion C., Arteaga C.L., King M.C., Jensen R.A. Growth retardation and tumour inhibition by BRCA1. Nat. Genet. 12:1996;298.
37. Sanchez Y., Desany B.A., Jones W.J., Liu Q., Wang B., Elledge S.J. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science. 271:1996;357.
38. Huang M., Zhou Z., Elledge S.J. The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell. 94:1998;595.
39. Zhou Z., Elledge S.J. DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell. 75:1993;1119.
40. Toczyski D.P., Galgoczy D.J., Hartwell L.H. CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell. 90:1997;1097.
41. Kitamoto H.K., Jablonowski D., Nagase J., Schaffrath R. Defects in yeast RNA polymerase II transcription elicit hypersensitivity to G1 arrest induced by Kluyveromyces lactis zymocin. Mol. Genet. Genomics. 268:2002;49.
42. Chang M., French-Cornay D., Fan H.Y., Klein H., Denis C.L., Jaehning J.A. A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling. Mol. Cell. Biol. 19:1999;1056.
43. Pearce A.K., Humphrey T.C. Integrating stress-response and cell-cycle checkpoint pathways. Trends Cell. Biol. 11:2001;426.
44. Akao Y., et al. The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations. Cancer Res. 52:1992;6083.
45. Arai Y., Hosoda F., Kobayashi H., Arai K., Hayashi Y., Kamada N., Kaneko Y., Ohki M. The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10. Blood. 89:1997;3936.
46. Smillie D.A., Sommerville J. RNA helicase p54 (DDX6) is a shuttling protein involved in nuclear assembly of stored mRNP particles. J. Cell Sci. 115:2002;395.
47. Jin C., Reed J.C. Yeast and apoptosis. Nat. Rev. Mol. Cell. Biology. 3:2002;453.
48. Mazzoni C., Mancini P., Verdone L., Madeo F., Serafini A., Herker E., C F.A. truncated form of KILsm4p and the absence of factors involved in mRNA decapping trigger apoptosis in yeast. Mol. Cell. Biol. 14:2003;721.
49. Rouault J.P., Prevot D., Berthet C., Birot A.M., Billaud M., Magaud J.P., Corbo L. Interaction of BTG1 and p53-regulated BTG2 gene products with mCaf1, the murine homolog of a component of the yeast CCR4 transcriptional regulatory complex. J. Biol. Chem. 273:1998;22563.
50. Tirone F. The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family regulator in control of cell growth, differentiation, and DNA repair? J. Cell. Physiol. 187:2001;155.