Genomic scale mutant hunt identifies cell size homeostasis genes in S. cerevisiae

Current Biology

Volumn 12, Issue 23, 2002, Pages 1992-2001

  Zhang, Jian ^a   Schneider, Colette ^a   Ottmers, Lisa ^a   Rodriguez, Robert ^a   Day, Audra ^a   Markwardt, Jody ^a   Schneider, Brandt L ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C;

CELL CYCLE G1 PHASE; CELL MUTANT; CELL PROLIFERATION; CELL SIZE; EUKARYOTIC CELL; FUNGAL CELL; GENE DELETION; GENETIC REGULATION; HETEROZYGOSITY; HOMEOSTASIS; HOMOZYGOSITY; ARTICLE; CELL CYCLE; CYTOLOGY; GENETICS; GENOME; HETEROZYGOTE; HOMOZYGOTE; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

CELL CYCLE; CELL SIZE; GENE DELETION; GENOME, FUNGAL; HETEROZYGOTE; HOMEOSTASIS; HOMOZYGOTE; SACCHAROMYCES CEREVISIAE;

EID: 0036899862     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)01305-2     Document Type: Article

References (40)

1. Conlon, I., and Raff, M. (1999). Size control in animal development. Cell 96, 235-244.
2. Stocker, H., and Hafen, E. (2000). Genetic control of cell size. Curr. Opin. Genet. Dev. 10, 529-535.
3. Edgar, B.A. (1999). From small flies come big discoveries about size control. Nat. Cell Biol. 1, E191-193.
4. Fantes, P.A., Grant, W.D., Pritchard, R.H., Sudbery, P.E., and Wheals, A.E. (1975). The regulation of cell size and the control of mitosis. J. Theor. Biol. 50, 213-244.
5. Hartwell, L.H. (1974). Saccharomyces cerevisiae cell cycle. Bacteriol. Rev. 38, 164-198.
6. Tyers, M., Tokiwa, G., and Futcher, B. (1993). Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. EMBO J. 12, 1955-1968.
7. Nash, R., Tokiwa, G., Anand, S., Erickson, K., and Futcher, A.B. (1988). The WHI1 + gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog. EMBO J. 7, 4335-4346.
8. Dirick, L., Bohm, T., and Nasmyth, K. (1995). Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae. EMBO J. 14, 4803-4813.
9. Di Como, C.J., Chang, H., and Arndt, K.T. (1995). Activation of CLN1 and CLN2 G1 cyclin gene expression by BCK2. Mol. Cell. Biol. 15, 1835-1846.
10. Sudbery, P.E., Goodey, A.R., and Carter, B.L. (1980). Genes which control cell proliferation in the yeast Saccharomyces cerevisiae. Nature 288, 401-404.
11. Radcliffe, P., Trevethick, J., Tyers, M., and Sudbery, P. (1997). Deregulation of CLN1 and CLN2 in the Saccharomyces cerevisiae whi2 mutant. Yeast 13, 707-715.
12. Nash, R.S., Volpe, T., and Futcher, B. (2001). Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157, 1469-1480.
13. Hadwiger, J.A., Wittenberg, C., Richardson, H.E., de Barros Lopes, M., and Reed, S.I. (1989). A family of cyclin homologs that control the G1 phase in yeast. Proc. Natl. Acad. Sci. USA 86, 6255-6259.
14. Tyson, C.B., Lord, P.G., and Wheals, A.E. (1979). Dependency of size of Saccharomyces cerevisiae cells on growth rate. J. Bacteriol. 138, 92-98.
15. Kozma, S.C., and Thomas, G. (2002). Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K. Bioessays 24, 65-71.
16. Polymenis, M., and Schmidt, E.V. (1999). Coordination of cell growth with cell division. Curr. Opin. Genet. Dev. 9, 76-80.
17. Prober, D.A., and Edgar, B.A. (2001). Growth regulation by oncogenes-new insights from model organisms. Curr. Opin. Genet. Dev. 11, 19-26.
18. Pyronnet, S., and Sonenberg, N. (2001). Cell-cycle-dependent translational control. Curr. Opin. Genet. Dev. 11, 13-18.
19. Sudbery, P. (2002). Cell biology. When wee meets whi. Science 297, 351-352.
20. Winzeler, E.A., Shoemaker, D.D., Astromoff, A., Liang, H., Anderson, K., Andre, B., Bangham, R., Benito, R., Boeke, J.D., Bussey, H., et al. (1999). Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285, 901-906.
21. Russo, G.L., van den Bos, C., Sutton, A., Coccetti, P., Baroni, M.D., Alberghina, L., and Marshak, D.R. (2000). Phosphorylation of Cdc28 and regulation of cell size by the protein kinase CKII in Saccharomyces cerevisiae. Biochem. J. 351, 143-150.
22. Jorgensen, P., Nishikawa, J.L., Breitkreutz, B.J., and Tyers, M. (2002). Systematic identification of pathways that couple cell growth and division in yeast. Science 297, 395-400.
23. Dwight, S.S., Harris, M.A., Dolinski, K., Ball, C.A., Binkley, G., Christie, K.R., Fisk, D.G., Issel-Tarver, L., Schroeder, M., Sherlock, G., et al. (2002). Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO). Nucleic Acids Res. 1, 69-72.
24. Koch, C., and Nasmyth, K. (1994). Cell cycle regulated transcription in yeast. Curr. Opin. Cell Biol. 6, 451-459.
25. Spellman, P.T., Sherlock, G., Zhang, M.Q., Iyer, V.R., Anders, K., Eisen, M.B., Brown, P.O., Botstein, D., and Futcher, B. (1998). Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol. Biol. Cell 9, 3273-3297.
26. Chang, M., French-Cornay, D., Fan, H.Y., Klein, H., Denis, C.L., and Jaehning, J.A. (1999). A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling. Mol. Cell. Biol. 19, 1056-1067.
27. Hall, D.D., Markwardt, D.D., Parviz, F., and Heideman, W. (1998). Regulation of the Cln3-Cdc28 kinase by cAMP in Saccharomyces cerevisiae. EMBO J. 17, 4370-4378.
28. Tokiwa, G., Tyers, M., Volpe, T., and Futcher, B. (1994). Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast. Nature 371, 342-345.
29. Baroni, M.D., Monti, P., and Alberghina, L. (1994). Repression of growth-regulated G1 cyclin expression by cyclic AMP in budding yeast. Nature 371, 339-342.
30. Nurse, P., and Thuriaux, P. (1977). Controls over the timing of DNA replication during cell cycle of fission yeast. Exp. Cell Res. 107, 365-375.
31. Fantes, P., and Nurse, P. (1977). Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division. Exp. Cell Res. 107, 377-386.
32. Gray, J.V., Ogas, J.P., Kamada, Y., Stone, M., Levin, D.E., and Herskowitz, I. (1997). A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator. EMBO J. 16, 4924-4937.
33. Koch, C., Wollmann, P., Dahl, M., and Lottspeich, F. (1999). A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast. Nucleic Acids Res. 27, 2126-2134.
34. Madden, K., Sheu, Y.J., Baetz, K., Andrews, B., and Snyder, M. (1997). SBF cell cycle regulator as a target of the yeast PKCMAP kinase pathway. Science 275, 1781-1784.
35. Igual, J.C., Johnson, A.L., and Johnston, L.H. (1996). Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity. EMBO J. 15, 5001-5013.
36. Ivanovska, I., and Rose, M.D. (2000). SLG1 plays a role during G1 in the decision to enter or exit the cell cycle. Mol. Gen. Genet. 262, 1147-1156.
37. Edgington, N.P., and Futcher, B. (2001). Relationship between the function and the location of G1 cyclins in S. cerevisiae. J. Cell Sci. 114, 4599-4611.
38. Diehl, J.A., Cheng, M., Roussel, M.F., and Sherr, C.J. (1998). Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 12, 3499-3511.
39. Ho, Y., Gruhler, A, Heilbut, A., Bader, G.D., Moore, L., Adams, S.L., Millar, A., Taylor, P., Bennett, K., Boutilier, K., et al. (2002). Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415, 180-183.
40. Schneider, B.L., Yang, Q.H., and Futcher, A.B. (1996). Linkage of replication to start by the Cdk inhibitor Sic1. Science 272, 560-562.