메뉴 건너뛰기




Volumn 86, Issue 1, 2003, Pages 93-98

DT56a (Tofupill®/Femarelle™) selectively stimulates creatine kinase specific activity in skeletal tissues of rats but not in the uterus

Author keywords

Bone; Cartilage; Creatine kinase; DT56a; Estradiol; Phytoestrogens; Raloxifene; Uterus

Indexed keywords

CREATINE KINASE BB; ESTRADIOL; PHYTOESTROGEN; PLANT EXTRACT; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TOFUPILL; CREATINE KINASE; DT56A; ESTROGEN; ISOENZYME; ISOFLAVONE DERIVATIVE; PLANT MEDICINAL PRODUCT;

EID: 0041424883     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(03)00252-8     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 0037157169 scopus 로고    scopus 로고
    • Effect of lower doses of conjugated equine estrogens with and without medroxyprogesterone acetate on bone in early postmenopausal women
    • Lindsay R., Gallagher J.C., Kleerekoper M., Pickar J.H. Effect of lower doses of conjugated equine estrogens with and without medroxyprogesterone acetate on bone in early postmenopausal women. J. Am. Med. Assoc. 287:2002;2668-2676.
    • (2002) J. Am. Med. Assoc. , vol.287 , pp. 2668-2676
    • Lindsay, R.1    Gallagher, J.C.2    Kleerekoper, M.3    Pickar, J.H.4
  • 2
    • 0029992572 scopus 로고    scopus 로고
    • The comparative effect on bone density, endometrium, and lipids of continuous hormones as replacement therapy (CHART study). A randomized controlled trial
    • Speroff L., Rowan J., Symons J., Genant H., Wilborn W. The comparative effect on bone density, endometrium, and lipids of continuous hormones as replacement therapy (CHART study). A randomized controlled trial. J. Am. Med. Assoc. 276:1996;1397-1403.
    • (1996) J. Am. Med. Assoc. , vol.276 , pp. 1397-1403
    • Speroff, L.1    Rowan, J.2    Symons, J.3    Genant, H.4    Wilborn, W.5
  • 4
    • 0032813510 scopus 로고    scopus 로고
    • Oestrogen receptors - An overview
    • Enmark E., Gustafsson J.A. Oestrogen receptors - an overview. J. Int. Med. 246:1999;133-138.
    • (1999) J. Int. Med. , vol.246 , pp. 133-138
    • Enmark, E.1    Gustafsson, J.A.2
  • 5
    • 0032561362 scopus 로고    scopus 로고
    • Differential classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain
    • Eng F.C., Barsalou A., Akutsu N., Mercier N., Zechel C., Mader S., White J.H. Differential classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain. J. Biol. Chem. 273:1998;28371-28377.
    • (1998) J. Biol. Chem. , vol.273 , pp. 28371-28377
    • Eng, F.C.1    Barsalou, A.2    Akutsu, N.3    Mercier, N.4    Zechel, C.5    Mader, S.6    White, J.H.7
  • 6
    • 0030946198 scopus 로고    scopus 로고
    • Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen 4-hydroxy tamoxifen
    • Smith C.L., Nawaz Z., O'Malley B.W. Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen 4-hydroxy tamoxifen. Mol. Endocrinol. 11:1997;657-666.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 657-666
    • Smith, C.L.1    Nawaz, Z.2    O'Malley, B.W.3
  • 7
    • 0030059053 scopus 로고    scopus 로고
    • Current management of breast cancer
    • Philips D.M., Balducci L. Current management of breast cancer. Am. Fam. Physician. 53:1996;657-665.
    • (1996) Am. Fam. Physician , vol.53 , pp. 657-665
    • Philips, D.M.1    Balducci, L.2
  • 8
    • 0033781929 scopus 로고    scopus 로고
    • Raloxifene: A selective estrogen receptor modulator (SERM) with multiple target system effects
    • Muchmore D.B. Raloxifene: a selective estrogen receptor modulator (SERM) with multiple target system effects. Oncologist. 5:2000;388-392.
    • (2000) Oncologist , vol.5 , pp. 388-392
    • Muchmore, D.B.1
  • 9
    • 0037138787 scopus 로고    scopus 로고
    • Raloxifene and cardiovascular events in osteoporotic postmenopausal women: 4-year results from the MORE (multiple outcomes of raloxifene evaluation) randomized trial
    • Barrett-Connor E., Grady D., Sashegyi A., Anderson P.W. Raloxifene and cardiovascular events in osteoporotic postmenopausal women: 4-year results from the MORE (multiple outcomes of raloxifene evaluation) randomized trial. J. Am. Med. Assoc. 287:2002;847-857.
    • (2002) J. Am. Med. Assoc. , vol.287 , pp. 847-857
    • Barrett-Connor, E.1    Grady, D.2    Sashegyi, A.3    Anderson, P.W.4
  • 10
    • 0032098310 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators
    • Kearney C.E., Purdie D.W. Selective estrogen receptor modulators. Climacteric. 1:1998;143-147.
    • (1998) Climacteric , vol.1 , pp. 143-147
    • Kearney, C.E.1    Purdie, D.W.2
  • 11
    • 0036189150 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators as a new therapeutic drug group: Concept to reality in a decade
    • Gajdos C., Jordan V.C. Selective estrogen receptor modulators as a new therapeutic drug group: concept to reality in a decade. Clin. Breast Cancer. 2:2002;272-281.
    • (2002) Clin. Breast Cancer , vol.2 , pp. 272-281
    • Gajdos, C.1    Jordan, V.C.2
  • 12
    • 0032116898 scopus 로고    scopus 로고
    • Potential health benefits of dietary phyto-estrogens: A review of the clinical, epidemiological, and mechanistic evidence
    • Tham D.M., Gardner C.D., Haskell W.L. Potential health benefits of dietary phyto-estrogens: a review of the clinical, epidemiological, and mechanistic evidence. J. Clin. Endocrinol. Metab. 83:1998;2223-2235.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 2223-2235
    • Tham, D.M.1    Gardner, C.D.2    Haskell, W.L.3
  • 13
    • 0031741906 scopus 로고    scopus 로고
    • Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones
    • Setchell K.D.R. Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. Am. J. Clin. Nutr. 68(Suppl):1998;1333S-1346S.
    • (1998) Am. J. Clin. Nutr. , vol.68 , Issue.SUPPL.
    • Setchell, K.D.R.1
  • 14
    • 0031826719 scopus 로고    scopus 로고
    • Effects of tamoxifen on bone fractures in older nursing home residents
    • Breuer B., Wallenstein S., Anderson R. Effects of tamoxifen on bone fractures in older nursing home residents. J. Am. Geriatr. Soc. 46:1998;968-972.
    • (1998) J. Am. Geriatr. Soc. , vol.46 , pp. 968-972
    • Breuer, B.1    Wallenstein, S.2    Anderson, R.3
  • 15
    • 0036375102 scopus 로고    scopus 로고
    • Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators
    • McDonnell D.P., Connor C.E., Wijayaratne A., Chang C.Y., Norris J.D. Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators. Recent Prog. Horm. Res. 57:2002;295-316.
    • (2002) Recent Prog. Horm. Res. , vol.57 , pp. 295-316
    • McDonnell, D.P.1    Connor, C.E.2    Wijayaratne, A.3    Chang, C.Y.4    Norris, J.D.5
  • 16
    • 0033368173 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Tissue selectivity and differential uterine effects
    • Silfen S.L., Ciaccia A.V., Bryant H.U. Selective estrogen receptor modulators: tissue selectivity and differential uterine effects. Climateric. 2:1999;268-283.
    • (1999) Climateric , vol.2 , pp. 268-283
    • Silfen, S.L.1    Ciaccia, A.V.2    Bryant, H.U.3
  • 17
    • 0030450585 scopus 로고    scopus 로고
    • Tissue selective action of tamoxifen methiodide, raloxifene and tamoxifen on creatine kinase B activity in vitro and in vivo
    • Somjen D., Waisman A., Kaye A.M. Tissue selective action of tamoxifen methiodide, raloxifene and tamoxifen on creatine kinase B activity in vitro and in vivo. J. Steroid Biochem. Mol. Biol. 59:1996;389-396.
    • (1996) J. Steroid Biochem. Mol. Biol. , vol.59 , pp. 389-396
    • Somjen, D.1    Waisman, A.2    Kaye, A.M.3
  • 18
    • 0031772172 scopus 로고    scopus 로고
    • Soy protein and isoflavones: Their effects on blood lipids and bone density in postmenopausal women
    • Potter S.M., Baum J.A., Teng H., Stillman R.J., Shay N.F., Erdman J.W. Jr. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. Am. J. Clin. Nutr. 68(Suppl):1998;1375S-1379S.
    • (1998) Am. J. Clin. Nutr. , vol.68 , Issue.SUPPL.
    • Potter, S.M.1    Baum, J.A.2    Teng, H.3    Stillman, R.J.4    Shay, N.F.5    Erdman J.W., Jr.6
  • 19
    • 0036245076 scopus 로고    scopus 로고
    • Phytoestrogens in the management of the menopause: Up-to-date
    • Ewies A.A. Phytoestrogens in the management of the menopause: up-to-date. Obstet. Gynecol. Surv. 57:2002;306-313.
    • (2002) Obstet. Gynecol. Surv. , vol.57 , pp. 306-313
    • Ewies, A.A.1
  • 20
    • 0020562898 scopus 로고
    • Estrogen-induced creatine kinase in the reproductive system of the immature female rat
    • Malnick S.D., Shaer A., Soreq H., Kaye A.M. Estrogen-induced creatine kinase in the reproductive system of the immature female rat. Endocrinology. 113:1983;1907-1909.
    • (1983) Endocrinology , vol.113 , pp. 1907-1909
    • Malnick, S.D.1    Shaer, A.2    Soreq, H.3    Kaye, A.M.4
  • 21
    • 3042643717 scopus 로고
    • Direct and sex-specific stimulation by sex steroids of creatine kinase activity and DNA synthesis in rat bone
    • Somjen D., Weisman Y., Harell A., Berger E., Kaye A.M. Direct and sex-specific stimulation by sex steroids of creatine kinase activity and DNA synthesis in rat bone. Proc. Natl. Acad. Sci. U.S.A. 86:1989;3361-3365.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 3361-3365
    • Somjen, D.1    Weisman, Y.2    Harell, A.3    Berger, E.4    Kaye, A.M.5
  • 22
    • 0032077009 scopus 로고    scopus 로고
    • Nonhypercalcemic analogs of vitamin D stimulate creatine kinase B activity in osteoblast-like ROS 17/2.8 cells and up-regulate their responsiveness to estrogens
    • Somjen D., Waissman A., Weisman Y., Kaye A.M. Nonhypercalcemic analogs of vitamin D stimulate creatine kinase B activity in osteoblast-like ROS 17/2.8 cells and up-regulate their responsiveness to estrogens. Steroids. 63:1998;340-343.
    • (1998) Steroids , vol.63 , pp. 340-343
    • Somjen, D.1    Waissman, A.2    Weisman, Y.3    Kaye, A.M.4
  • 23
  • 24
    • 0011216192 scopus 로고    scopus 로고
    • Mass balance study of isoflavones during soybean processing
    • Wang H.J., Murphy P.A. Mass balance study of isoflavones during soybean processing. J. Agric. Food Chem. 44:1996;2377-2383.
    • (1996) J. Agric. Food Chem. , vol.44 , pp. 2377-2383
    • Wang, H.J.1    Murphy, P.A.2
  • 25
    • 0042249632 scopus 로고    scopus 로고
    • Phytoestrogens: A time-tested solution for menopausal symptoms revisited
    • Yoles I., Kaplan B., Seidman D.S., Chayen B. Phytoestrogens: a time-tested solution for menopausal symptoms revisited. Obstet. Gynecol. 99(Suppl):2002;58S.
    • (2002) Obstet. Gynecol. , vol.99 , Issue.SUPPL.
    • Yoles, I.1    Kaplan, B.2    Seidman, D.S.3    Chayen, B.4
  • 26
    • 0023320347 scopus 로고
    • The effect of ovariectomy and 17b-estradiol on bone histomorphometry in growing rats
    • Turner R.T., van der Steenhover J.J., Bell N.H. The effect of ovariectomy and 17b-estradiol on bone histomorphometry in growing rats. J. Bone Mineral. Res. 2:1987;115-122.
    • (1987) J. Bone Mineral. Res. , vol.2 , pp. 115-122
    • Turner, R.T.1    Van der Steenhover, J.J.2    Bell, N.H.3
  • 27
    • 0028157566 scopus 로고
    • Age dependence and modulation by gonadectomy of the sex-specific response of rat diaphyseal bone to gonadal steroids
    • Somjen D., Mor Z., Kaye A.M. Age dependence and modulation by gonadectomy of the sex-specific response of rat diaphyseal bone to gonadal steroids. Endocrinology. 134:1994;809-814.
    • (1994) Endocrinology , vol.134 , pp. 809-814
    • Somjen, D.1    Mor, Z.2    Kaye, A.M.3
  • 28
    • 0034667496 scopus 로고    scopus 로고
    • Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells
    • Tamir S., Eizenberg M., Somjen D., Izrael S., Vaya J. Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells. Cancer Res. 60:2000;5704-5709.
    • (2000) Cancer Res. , vol.60 , pp. 5704-5709
    • Tamir, S.1    Eizenberg, M.2    Somjen, D.3    Izrael, S.4    Vaya, J.5
  • 30
    • 0034541315 scopus 로고    scopus 로고
    • Extraction and quantification of lignan phytoestrogens in food and human samples
    • Liggins J., Grimwood R., Bingham S.A. Extraction and quantification of lignan phytoestrogens in food and human samples. Anal. Biochem. 287:2000;102-109.
    • (2000) Anal. Biochem. , vol.287 , pp. 102-109
    • Liggins, J.1    Grimwood, R.2    Bingham, S.A.3
  • 31
    • 0033896482 scopus 로고    scopus 로고
    • The therapeutic potential of phytoestrogens
    • Wiseman H. The therapeutic potential of phytoestrogens. Exp. Opin. Investig. Drugs. 9:2000;1829-1840.
    • (2000) Exp. Opin. Investig. Drugs , vol.9 , pp. 1829-1840
    • Wiseman, H.1
  • 33
    • 0031734143 scopus 로고    scopus 로고
    • Soy, its components and cancer prevention: A review of the in vitro, animal and human data
    • Fournier B.F., Erdman J.W. Jr., Gordon G.B. Soy, its components and cancer prevention: a review of the in vitro, animal and human data. Cancer Epidemiol. Biomarkers Prev. 7:1998;1055-1065.
    • (1998) Cancer Epidemiol. Biomarkers Prev. , vol.7 , pp. 1055-1065
    • Fournier, B.F.1    Erdman J.W., Jr.2    Gordon, G.B.3
  • 37
    • 0031015553 scopus 로고    scopus 로고
    • Anabolic effects of estrogen and parathyroid hormone on skeletal tissues: The use of creatine kinase B activity as a response marker
    • Kaye A.M., Kim T.-Y., Kohen F., Somjen D. Anabolic effects of estrogen and parathyroid hormone on skeletal tissues: the use of creatine kinase B activity as a response marker. Arch. Gerontol. Geriatr. 24:1997;197-209.
    • (1997) Arch. Gerontol. Geriatr. , vol.24 , pp. 197-209
    • Kaye, A.M.1    Kim, T.-Y.2    Kohen, F.3    Somjen, D.4
  • 38
    • 0036139780 scopus 로고    scopus 로고
    • Selective anabolic effects of muteins of mid-region PTH fragments on skeletal tissues of prepubertal rats
    • Kim T.-Y., Vargas V., Mayer H., Somjen D., Kaye A.M. Selective anabolic effects of muteins of mid-region PTH fragments on skeletal tissues of prepubertal rats. Bone. 30:2002;78-84.
    • (2002) Bone , vol.30 , pp. 78-84
    • Kim, T.-Y.1    Vargas, V.2    Mayer, H.3    Somjen, D.4    Kaye, A.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.