Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures

Development

Volumn 127, Issue 9, 2000, Pages 1833-1843

  Xu, Jingsong ^a   Liu, Zhonghao ^a   Ornitz, David M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Central nervous system; Cerebellum; FGF; FGF17; FGF8; Fibroblast growth factor; Mouse; Neuronal differentiation factor; Neuronal growth factor; Organizer

Indexed keywords

FIBROBLAST GROWTH FACTOR 8;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CELL PROLIFERATION; CEREBELLAR ATAXIA; CEREBELLUM VERMIS; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO PATTERN FORMATION; GENE DISRUPTION; GENE DOSAGE; MESENCEPHALON; MOUSE; NEUROEPITHELIUM; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RHOMBENCEPHALON;

ANIMALS; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELL DIFFERENTIATION; CELL DIVISION; CELL MOVEMENT; CEREBELLUM; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; HISTOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; PHENOTYPE; SIGNAL TRANSDUCTION;

ANIMALIA; ATAXIA; VERTEBRATA;

EID: 0034023520     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Altman, J. and Bayer, S. A. (1985). Embryonic development of the rat cerebellum. III. Regional differences in the time of origin, migration, and settling of Purkinje cells. J. Comp. Neurol. 231, 42-65.
2. Altman, J. and Bayer, S. A. (1997). Development of the Cerebellar System: In Relation to its Evolution, Structure and Functions. New York: CRC press.
3. Alvarez Otero, R., Sotelo, C. and Alvarado-Mallart, R. M. (1993). Chick/quail chimeras with partial cerehellar grafts: an analysis of the origin and migration of cerebellar cells. J. Comp. Neurol. 333, 597-615.
4. Bally-Cuif, L., Alvarado-Mallart, R. M., Darnell, D. K. and Wassef, M. (1992). Relationship between Wnt-1 and En-2 expression domains during early development of normal and ectopic met-mesencephalon. Development 115, 999-1009.
5. Brodal, P. (1998). The Central Nervous System: Structure and Function. Oxford: Oxford University Press.
6. Chisaka, O. and Capecchi, M. R. (1991). Regionally restricted development defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature 350, 473-479.
7. Coulier, F., Pontarolti, P., Roubin, R., Hartung, H., Goldfarb, M. and Birnbaum, D. (1997). Of worms and men: an evolutionary perspective on the fibroblast growth factor (FGF) and FGF receptor families. J. Mol. Evol. 44, 43-56.
8. Crossley, P. H., Martinez, S. and Martin, G. R. ( 1996). Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.
9. Gardner, C. A. and Barald, K. F. (1991). The cellular environment controls the expression ol engrailed-like protein in the cranial neuroepithelinm of quail-chick chimeric embryos. Development 113, 1037-48.
10. Gritti, A., Parati, E. A., Cova, L., Frolichsthal, P., Galli, R., Wanke, E., Faravelli, L., et al. (1996). Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J. Neurosci. 16, 1091-100.
11. Hallonet, M. and Alvaradomallart, R. M. (1997). The chick/quail chimeric system - a model for early cerebellar development. Perspec. Dev. Neurol. 5, 17-31.
12. Hallonet, M. E. and Le Douarin, N. M. (1993). Tracing neuroepithelial cells of the mesencephalic and metencephalic alar plates during cerebellar ontogeny in quail-chick chimaeras. Eur. J. Neurosci. 5, 1145-55.
13. Hatten, M. E. and Heintz, N. (1995). Mechanisms of neural patterning and specification in the developing cerebellum. Annul. Rev. Neurosci. 18, 385-408.
14. Hogan, B. L. M. and Yingling, J. M. (1998) Epithelial/Mesenchymal Interactions and Branching Morphogenesis of the Lung. Curr. Opin. Genet. Devel. 8, 481-486.
15. Itasaki, N., Ichijo, H., Hama, C., Matsuno, T. and Nakamura, H. (1991). Establishment of rostrocaudal polarity in tectal primordiurn: engrailed expression and subsequent tectal polarity. Development 113, 1133-44.
16. Johe, K. K., Hazel, T. G., Muller, T., Dugich-Djordjevic, M. M. and McKay, R. D. (1996). Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 10, 3129-40.
17. Joyner, A. L. (1996). Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development. Trends Genet. 12, 15-20.
18. Lee, S. M., Danielian, P. S., Fritzsch, B. and McMahon, A. P. (1997). Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124, 959-969.
19. Lewandoski, M., Wassarman, K. M. and Martin, G. R. (1997). Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line. Curr. Biol. 7, 148-51.
20. Liu, A., Losos, K. and Joyner, A. L. (1999). FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindhrain fate. Development 126, 4827-4838.
21. Marin, F. and Puelles, L. (1995). Morphological fate of rhombomeres in quail/chick chimeras: a segmental analysis of hindbrain nuclei. Eur. J. Neurosci. 7, 1714-38.
22. Martinez, S., Crossley, P. H., Cobos, I., Rubenstein, J. L. and Martin, G. R. (1999). FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development 126, 1189-200.
23. Martinez, S., Wassef, M. and Alvarado-Mallart, R. M. (1991). Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en. Neuron 6, 971-81.
24. Maruoka, Y., Ohbayashi, N., Hoshikawa, M., Itoh, N., Hogan, B. L. M. and Furuta, Y. (1998). Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo. Mech. Dev. 74, 175-177.
25. McKeehan, W. L., Wang, F. and Kan, M. (1998). The heparan sulfate-fibroblast growth factor family: diversity of structure and function. Prog. Nucleic Acid Res. Mol. Biol. 59, 135-176.
26. - mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell 69, 581-95.
27. McWhirter, J. R., Goulding, M., Weiner, J. A., Chun, J. and Murre, C. (1997). A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. Development 124, 3221-3232.
28. Meyers, E. N., Lewandoski, M. and Martin, G. R. (1998). An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat. Genet. 18, 136-141.
29. Naski, M. C., Colvin, J. S., Coffin, J. D. and Ornitz, D. M. (1998). Repression of hedgehog signaling and BMP4 expression by fibroblast growth factor receptor 3 in growth plate cartilage of transgenic mice. Development 125, 4977-4988.
30. Naski, M. C. and Ornitz, D. M. (1998). FGF signaling in skeletal development, Front. Biosci. 3, D781-794.
31. Nishimura, T., Utsunomiya, Y., Hoshikawa, M., Ohuchi, H. and Itoh, N. (1999). Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain. Biochem. Biophys. Acta 1444, 148-151.
32. Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G., et al. (1996). Receptor specificity of the fibroblast growth factor family. J. Biol. Chem. 271, 15292-15297.
33. Reifers, F., Bohli, H., Walsh, E. C., Crossley, P. H., Stainier, D. Y. and Brand, M. (1998). Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125, 2381-95.
34. Schwarz, M., Alvarez-Bolado, G., Dressler, G., Urbanek, P., Busslinger, M. and Gruss, P. (1999). Pax2/5 and Pax6 subdivide the early neural tube into three domains. Mech. Dev. 82, 29-39.
35. Shamim, H., Mahmood, R., Logan, C., Doherty, P., Lumsden, A. and Mason, I. (1999). Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbram. Development 126, 945-59.
36. Sheikh, H. and Mason, I. (1996). Polarising activity of FGF-8 in the avian midbrain. Int. J. Dev. Biol. Supplement. 117S-118S.
37. Szebenyi, G. and Fallon, J. F. (1999). Fibroblast growth factors as multifunctional signaling factors. Int. Rev. Cyt. 185, 45-106.
38. Tybulewicz, V. L. J., Crawford, C. E., Jackson, P. K., Bronson, R. T. and Mulligan, R. C. (1991). Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65, 1153-1163.
39. Victor, M., Adams, R. D. and Mancall, E. L. (1959). A restricted form of cerebellar cortical degeneration occurring in alcoholic patients. Arch. Neurol. 1, 579-699.
40. Xu, J., Lawshe, A., MacArthur, C. A. and Ornitz, D. M. (1999). Genomic structure, mapping, activity and expression of fibroblast growth factor 17. Mech. Dev. 83, 165-78.
41. Yuasa, S., Kawamura, K., Ono, K., Yamakuni, T. and Takahashi, Y. (1991). Development and migration of Purkinje cells in the mouse cerebellar primordium. Anat. Embryol. 184, 195-212.