Synthesis of the C22-C26 tetrahydropyran segment of phorboxazole by a stereoselective Prins cyclization

Organic Letters

Volumn 2, Issue 9, 2000, Pages 1217-1219

  Rychnovsky, Scott D ^a   Thomas, Christian R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0041408703     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol005646a     Document Type: Article

References (46)

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44. Alcohol 9 was analyzed for optical purity by using a Chiralcel OD-H column with 98:2 hexane:i-PrOH as the eluent, using the racemate as a standard. The 3R,4R enantiomer (9) eluted first.
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46. The X-ray data are available as Supporting Information. We thank Dr. Joe Ziller for determining the structure of 14.