Prins cyclization of 4-allyl-1,3-dioxanes prepared from 1,3-diol synthons. A rapid entry into functionalized tetrahydropyrans

Tetrahedron Letters

Volumn 37, Issue 48, 1996, Pages 8679-8682

  Hu, Yueqing ^a   Skalitzky, Donald J ^a   Rychnovsky, Scott D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

1,3 diols; Prins cyclization; Tetrahydropyrans

Indexed keywords

1,3 DIOXANE DERIVATIVE; TETRAHYDROPYRAN DERIVATIVE;

ALKYLATION; ARTICLE; CYCLIZATION; DIASTEREOISOMER; STEREOCHEMISTRY; SYNTHESIS;

EID: 0030602166     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02008-4     Document Type: Article

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20. 13 Tetrahydropyran 16 (X = F, entry 4) was produced as a 2:1 mixture of equatorial and axial fluorides.
21. 14 This work was supported by the NIH, the NSF, and Pfizer, Inc.