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Volumn 285, Issue 2 29-2, 2003, Pages

Contractile activity and smooth muscle α-actin organization in thrombin-induced human lung myofibroblasts

Author keywords

Fibroblast differentiation; Protein kinase C ; RhoA

Indexed keywords

ALPHA ACTIN; COLLAGEN GEL; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); PROTEIN KINASE C EPSILON; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBIN;

EID: 0041343259     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00417.2002     Document Type: Article
Times cited : (61)

References (47)
  • 2
    • 0035976915 scopus 로고    scopus 로고
    • Thrombin differentiates normal lung fibroblasts to a myofibroblast phenotype via proteolytically activated receptor-1 and a protein kinase C-dependent pathway
    • Bogatkevich GS, Tourkina E, Silver RM, and Ludwicka-Bradley A. Thrombin differentiates normal lung fibroblasts to a myofibroblast phenotype via proteolytically activated receptor-1 and a protein kinase C-dependent pathway. J Biol Chem 276: 45184-45192, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 45184-45192
    • Bogatkevich, G.S.1    Tourkina, E.2    Silver, R.M.3    Ludwicka-Bradley, A.4
  • 4
    • 0034102483 scopus 로고    scopus 로고
    • Actin cytoskeleton and cell signaling
    • Carpenter CL. Actin cytoskeleton and cell signaling. Crit Care Med 28 Suppl: N94-N99, 2000.
    • (2000) Crit Care Med , vol.28 , Issue.SUPPL.
    • Carpenter, C.L.1
  • 6
    • 0035823602 scopus 로고    scopus 로고
    • G-protein-coupled receptor activation induces the membrane translocation and activation of phosphatidylinositol-4-phosphate 5-kinase Iα by a Rac- and Rho-dependent pathway
    • Chatah NE and Abrams CS. G-protein-coupled receptor activation induces the membrane translocation and activation of phosphatidylinositol-4-phosphate 5-kinase Iα by a Rac- and Rho-dependent pathway. J Biol Chem 276: 34059-34065, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 34059-34065
    • Chatah, N.E.1    Abrams, C.S.2
  • 7
    • 0037023691 scopus 로고    scopus 로고
    • Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation
    • Chikumi H, Fukuhara S, and Gutkind JS. Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation. J Biol Chem 277: 12463-12473, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 12463-12473
    • Chikumi, H.1    Fukuhara, S.2    Gutkind, J.S.3
  • 8
    • 0024410410 scopus 로고
    • Functional sorting of actin isoforms in microvascular pericytes
    • DeNofrio D, Hoock TC, and Herman IM. Functional sorting of actin isoforms in microvascular pericytes. J Cell Biol 109: 191-202, 1989.
    • (1989) J Cell Biol , vol.109 , pp. 191-202
    • DeNofrio, D.1    Hoock, T.C.2    Herman, I.M.3
  • 9
    • 0028911139 scopus 로고
    • Analysis of the role of protein kinase C in T cell activation
    • Genot EM, Parker PJ, and Cantrell DA. Analysis of the role of protein kinase C in T cell activation. J Biol Chem 270: 9833-9839, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 9833-9839
    • Genot, E.M.1    Parker, P.J.2    Cantrell, D.A.3
  • 11
    • 0033618273 scopus 로고    scopus 로고
    • Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement
    • Hu MH, Bauman EM, Roll RL, Yeilding N, and Abrams CS. Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement. J Biol Chem 274: 21515-21518, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 21515-21518
    • Hu, M.H.1    Bauman, E.M.2    Roll, R.L.3    Yeilding, N.4    Abrams, C.S.5
  • 13
    • 0035071665 scopus 로고    scopus 로고
    • Functional specificity of actin isoforms
    • Khaitlina SY. Functional specificity of actin isoforms. Int Rev Cytol 202: 35-98, 2001.
    • (2001) Int Rev Cytol , vol.202 , pp. 35-98
    • Khaitlina, S.Y.1
  • 15
    • 0028986034 scopus 로고
    • The Ras-related protein Cdc 42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
    • Kozma R, Ahmed S, Best A, and Lim L. The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol Cell Biol 15: 1942-1952, 1995.
    • (1995) Mol Cell Biol , vol.15 , pp. 1942-1952
    • Kozma, R.1    Ahmed, S.2    Best, A.3    Lim, L.4
  • 17
    • 0025729855 scopus 로고
    • The roles of the myofibroblast in idiopathic pulmonary fibrosis
    • Kuhn C and McDonald JA. The roles of the myofibroblast in idiopathic pulmonary fibrosis. Am J Pathol 138: 1257-1265, 1991.
    • (1991) Am J Pathol , vol.138 , pp. 1257-1265
    • Kuhn, C.1    McDonald, J.A.2
  • 18
    • 0030977123 scopus 로고    scopus 로고
    • Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation
    • Kureishi Y, Kobayashi S, Amano M, Kimura K, Kanaide H, Nakano T, Kaibuchi K, and Ito M. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem 272: 12257-12260, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 12257-12260
    • Kureishi, Y.1    Kobayashi, S.2    Amano, M.3    Kimura, K.4    Kanaide, H.5    Nakano, T.6    Kaibuchi, K.7    Ito, M.8
  • 19
    • 0032616967 scopus 로고    scopus 로고
    • Modulation of myofibroblasts and smooth-muscle phenotypes in the lung
    • Low RB. Modulation of myofibroblasts and smooth-muscle phenotypes in the lung. Curr Top Pathol 93: 19-26, 1999.
    • (1999) Curr Top Pathol , vol.93 , pp. 19-26
    • Low, R.B.1
  • 22
    • 0035808389 scopus 로고    scopus 로고
    • Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization
    • Mack CP, Somlyo AV, Hautmann M, Somlyo AP, and Owens GK. Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. J Biol Chem 276: 341-347, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 341-347
    • Mack, C.P.1    Somlyo, A.V.2    Hautmann, M.3    Somlyo, A.P.4    Owens, G.K.5
  • 23
    • 0032562675 scopus 로고    scopus 로고
    • Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis
    • Majumdar M, Seasholtz TM, Goldstein D, de Lanerolle P, and Brown JH. Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis. J Biol Chem 273: 10099-10106, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 10099-10106
    • Majumdar, M.1    Seasholtz, T.M.2    Goldstein, D.3    De Lanerolle, P.4    Brown, J.H.5
  • 24
    • 0032054640 scopus 로고    scopus 로고
    • F-actin-binding proteins
    • McGough A. F-actin-binding proteins. Curr Opin Cell Biol 8: 166-176, 1996.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 166-176
    • McGough, A.1
  • 25
    • 0035933870 scopus 로고    scopus 로고
    • Protein kinase C-α signals Rho-guanine nucleotide dissociation inhibitor phosphorylation and Rho activation and regulates the endothelial cell barrier function
    • Mehta D, Rahman A, and Malik AB. Protein kinase C-α signals Rho-guanine nucleotide dissociation inhibitor phosphorylation and Rho activation and regulates the endothelial cell barrier function. J Biol Chem 276: 22614-22620, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 22614-22620
    • Mehta, D.1    Rahman, A.2    Malik, A.B.3
  • 27
    • 0034141607 scopus 로고    scopus 로고
    • Regulation of LPA-promoted myofibroblast contraction: Role of Rho, myosin light chain kinase, and myosin light chain phosphatase
    • Parizi M, Howard E, and Tomasek JJ. Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase. Exp Cell Res 254: 210-220, 2000.
    • (2000) Exp Cell Res , vol.254 , pp. 210-220
    • Parizi, M.1    Howard, E.2    Tomasek, J.J.3
  • 28
    • 0029887282 scopus 로고    scopus 로고
    • Role of the myofibroblast in pulmonary fibrosis
    • Phan SH. Role of the myofibroblast in pulmonary fibrosis. Kidney Int 49: S46-S48, 1996.
    • (1996) Kidney Int , vol.49
    • Phan, S.H.1
  • 29
    • 0032601635 scopus 로고    scopus 로고
    • The myofibroblast as an inflammatory cell in pulmonary fibrosis
    • Phan SH, Zhang K, Zhang HY, and Gharaee-Kermani M. The myofibroblast as an inflammatory cell in pulmonary fibrosis. Curr Top Pathol 93: 173-182, 1999.
    • (1999) Curr Top Pathol , vol.93 , pp. 173-182
    • Phan, S.H.1    Zhang, K.2    Zhang, H.Y.3    Gharaee-Kermani, M.4
  • 30
    • 0032500583 scopus 로고    scopus 로고
    • Molecular analysis of the interactions between protein kinase C-ε and filamentous actin
    • Prekeris R, Hernandez RM, Mayhew MW, White MK, and Terrian DM. Molecular analysis of the interactions between protein kinase C-ε and filamentous actin. J Biol Chem 273: 26790-26798, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 26790-26798
    • Prekeris, R.1    Hernandez, R.M.2    Mayhew, M.W.3    White, M.K.4    Terrian, D.M.5
  • 32
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the Rho-binding domain
    • Reid T, Furuyashiki T, Ishizaki T, Watanabe N, Fujisawa K, Morii N, Madaule P, and Narumiya S. Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the Rho-binding domain. J Biol Chem 271:13556-13560, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 13556-13560
    • Reid, T.1    Furuyashiki, T.2    Ishizaki, T.3    Watanabe, N.4    Fujisawa, K.5    Morii, N.6    Madaule, P.7    Narumiya, S.8
  • 33
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren XD, Kiosses WB, and Schwartz MA. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 18: 578-585, 1999.
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 34
    • 0028321785 scopus 로고
    • Signal transduction pathways regulating Rho-mediated stress fiber formation: Requirement for a tyrosine kinase
    • Ridley AJ and Hall A. Signal transduction pathways regulating Rho-mediated stress fiber formation: requirement for a tyrosine kinase. EMBO J 13: 2600-2610, 1994.
    • (1994) EMBO J , vol.13 , pp. 2600-2610
    • Ridley, A.J.1    Hall, A.2
  • 35
    • 0026654125 scopus 로고
    • The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling
    • Ridley AJ, Paterson HF, Johnston CL, Diekmann D, and Hall A. The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling. Cell 70: 401-410, 1992.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 36
    • 0033612371 scopus 로고    scopus 로고
    • Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration
    • Seasholtz TM, Majumdar M, Kaplan DD, and Brown JH. Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration. Circ Res 84: 1186-1193, 1999.
    • (1999) Circ Res , vol.84 , pp. 1186-1193
    • Seasholtz, T.M.1    Majumdar, M.2    Kaplan, D.D.3    Brown, J.H.4
  • 37
    • 0035836522 scopus 로고    scopus 로고
    • Interaction of protein kinase C isozymes with Rho GTPases
    • Slater SJ, Seiz JL, Stagliano BA, and Stubbs CD. Interaction of protein kinase C isozymes with Rho GTPases. Biochemistry 40: 4437-4445, 2001.
    • (2001) Biochemistry , vol.40 , pp. 4437-4445
    • Slater, S.J.1    Seiz, J.L.2    Stagliano, B.A.3    Stubbs, C.D.4
  • 39
    • 0034631516 scopus 로고    scopus 로고
    • Inhibition of PKC-α and RhoA translocation in differentiated smooth muscle by a caveolin scaffolding domain peptide
    • Taggart MJ, Leavis P, Feron O, and Morgan KG. Inhibition of PKC-α and RhoA translocation in differentiated smooth muscle by a caveolin scaffolding domain peptide. Exp Cell Res 258: 72-81, 2000.
    • (2000) Exp Cell Res , vol.258 , pp. 72-81
    • Taggart, M.J.1    Leavis, P.2    Feron, O.3    Morgan, K.G.4
  • 41
  • 42
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signaling networks
    • Van Aelst L and D'Souza-Schorey C. Rho GTPases and signaling networks. Genes Dev 11: 2295-2322, 1997.
    • (1997) Genes Dev , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 43
    • 0027772698 scopus 로고
    • Rat alveolar myofibroblasts acquire α-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis
    • Vyalov SL, Gabbiani G, and Kapanci Y. Rat alveolar myofibroblasts acquire α-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis. Am J Pathol 143: 1754-1765, 1993.
    • (1993) Am J Pathol , vol.143 , pp. 1754-1765
    • Vyalov, S.L.1    Gabbiani, G.2    Kapanci, Y.3
  • 45
    • 0030022205 scopus 로고    scopus 로고
    • Lung fibroblast α-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis
    • Zhang H, Gharaee-Kermani M, Zhang K, Karmiol S, and Phan SH. Lung fibroblast α-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis. Am J Pathol 148: 527-537, 1996.
    • (1996) Am J Pathol , vol.148 , pp. 527-537
    • Zhang, H.1    Gharaee-Kermani, M.2    Zhang, K.3    Karmiol, S.4    Phan, S.H.5
  • 46
    • 0028278029 scopus 로고
    • Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis: A combined immunohistochemical and in situ hybridization
    • Zhang K, Rekhter MD, Gordon D, and Phan SH. Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis: a combined immunohistochemical and in situ hybridization. Am J Pathol 145: 114-125, 1994.
    • (1994) Am J Pathol , vol.145 , pp. 114-125
    • Zhang, K.1    Rekhter, M.D.2    Gordon, D.3    Phan, S.H.4
  • 47
    • 0032984388 scopus 로고    scopus 로고
    • Signaling pathways in thrombin-induced actin reorganization in pulmonary artery endothelial cells
    • Zhao Y and Davis HW. Signaling pathways in thrombin-induced actin reorganization in pulmonary artery endothelial cells. Exp Cell Res 25: 23-39, 1999.
    • (1999) Exp Cell Res , vol.25 , pp. 23-39
    • Zhao, Y.1    Davis, H.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.