Thrombin Differentiates Normal Lung Fibroblasts to a Myofibroblast Phenotype via the Proteolytically Activated Receptor-1 and a Protein Kinase C-dependent Pathway

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 45184-45192

  Bogatkevich, Galina S ^b   Tourkina, Elena ^b   Silver, Richard M ^b   Ludwicka Bradley, Anna ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GELS; METABOLISM; MUSCLE;

MICROVASCULAR INJURIES;

ENZYMES;

ALPHA ACTIN; ANTISENSE OLIGONUCLEOTIDE; COLLAGEN GEL; PROTEIN KINASE C; PROTEIN KINASE C EPSILON; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN; TRANSFORMING GROWTH FACTOR BETA; ACTIN; COLLAGEN; DNA; ISOENZYME; ISOPROTEIN;

ARTICLE; BLOOD VESSEL INJURY; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG FIBROBLAST; MUSCLE CONTRACTION; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCLERODERMA; SMOOTH MUSCLE; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; FIBROBLAST; LUNG; METABOLISM; PROTEIN BINDING; SERODIAGNOSIS; SYSTEMIC SCLEROSIS; TIME; WESTERN BLOTTING;

SCLERODERMA;

ACTINS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; COLLAGEN; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FIBROBLASTS; HUMAN; ISOENZYMES; LUNG; MUSCLE, SMOOTH; PHENOTYPE; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN KINASE C; SCLERODERMA, SYSTEMIC; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; THROMBIN; TIME FACTORS;

EID: 0035976915     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106441200     Document Type: Article

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