Overexpression of cMOAT (MRP2/ABCC2) is associated with decreased formation of platinum-DNA adducts and decreased G2-arrest in melanoma cells resistant to cisplatin

Journal of Investigative Dermatology

Volumn 121, Issue 1, 2003, Pages 172-176

  Liedert, Bernd ^a   Materna, Verena ^d   Schadendorf, Dirk ^b   Thomale, Jürgen ^a   Lage, Hermann ^c  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

^d NONE

Author keywords

ABCC2; Cisplatin; cMOAT; Drug resistance; Melanoma; MeWo; MRP2

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; CARBOPLATIN; CELL NUCLEUS DNA; CISPLATIN; DAUNORUBICIN; ETOPOSIDE; MULTIDRUG RESISTANCE PROTEIN 2; PLATINUM; VINCRISTINE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS RESISTANCE; DNA ADDUCT; DNA CROSS LINKING; DNA REPAIR; DRUG RESISTANCE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; KINETICS; MELANOMA; MELANOMA CELL; MITOSIS INHIBITION; MULTIDRUG RESISTANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0041342087     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12313.x     Document Type: Article

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