Molecular responses to photogenotoxic stress induced by the antibiotic lomefloxacin in human skin cells: From DNA damage to apoptosis

Journal of Investigative Dermatology

Volumn 121, Issue 3, 2003, Pages 596-606

  Marrot, Laurent ^a   Belaïdi, Jean Phillipe ^a   Jones, Christophe ^a   Perez, Phillipe ^a   Riou, Lydia ^b   Sarasin, Alain ^b   Meunier, Jean Roch ^a  

^a L'Oréal Research Center   (France)

^b Laboratory of Genetic Instability and Cancer   (France)

Author keywords

DNA damage; Fluoroquinolone; Melanogenesis; p53; Phototoxicity; Skin cells

Indexed keywords

ANTIOXIDANT; CASPASE 3; DIMER; GENOMIC DNA; HEME OXYGENASE 1; LOMEFLOXACIN; MONOPHENOL MONOOXYGENASE; PROTEIN P21; PROTEIN P53; PSORALEN; PYRIMIDINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CAUCASIAN; CELL CULTURE; CELL TYPE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG MECHANISM; ENZYME ACTIVITY; FAS LIGAND GENE; GADD45 GENE; GENE; GENOTOXICITY; HUMAN; HUMAN CELL; KERATINOCYTE; MDM2 GENE; MELANOCYTE; MOLECULAR BIOLOGY; MOLECULAR RESPONSE; PHOTOCARCINOGENESIS; PHOTOGENOTOXICITY; PHOTOTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN CELL; SKIN FIBROBLAST; SKIN TUMOR; STRESS; SUN EXPOSURE; SUNLIGHT; ULTRAVIOLET A RADIATION;

EID: 0041333150     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12422.x     Document Type: Article

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