X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 Å resolution

Biochemistry

Volumn 38, Issue 14, 1999, Pages 4266-4276

  Erskine, Peter T ^b   Norton, Ed ^b   Cooper, Jon B ^b   Lambert, Richard ^b   Coker, Alun ^b   Lewis, Gareth ^b   Spencer, Paul ^a,b   Sarwar, Mohammed ^b   Wood, Steve P ^b   Warren, Martin J ^c   Shoolingin Jordan, Peter M ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYSTEINE; DIMER; LEVULINIC ACID; LYSINE; MAGNESIUM; MONOMER; PORPHOBILINOGEN SYNTHASE; SERINE; TYROSINE; ZINC;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ESCHERICHIA COLI; HYDROGEN BOND; METAL BINDING; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ENZYME INHIBITORS; ESCHERICHIA COLI; LEVULINIC ACIDS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PORPHOBILINOGEN SYNTHASE; PROTEIN STRUCTURE, SECONDARY; ZINC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0033528697     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982137w     Document Type: Article

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