Lysophosphatidic acid induces α1B-adrenergic receptor phosphorylation through Gβγ, phosphoinositide 3-kinase, protein kinase C and epidermal growth factor receptor transactivation

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1633, Issue 2, 2003, Pages 75-83

  Casas González, Patricia ^a   Ruiz Martínez, Alejandro ^a   García Sáinz, J Adolfo ^a  

^a INSTITUTO DE FISIOLOGÍA CELULAR   (Mexico)

Author keywords

Phosphoinositide 3 kinase; Protein kinase C; Receptor phosphorylation; Receptor transactivation; 1B Adrenergic receptor

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; ALPHA 1B ADRENERGIC RECEPTOR; BATIMASTAT; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; METALLOPROTEINASE INHIBITOR; NORADRENALIN; PHORBOL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE INHIBITOR; STAUROSPORINE; WORTMANNIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSFECTION; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; TRANSACTIVATION;

EID: 0038825248     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-1981(03)00089-1     Document Type: Article

References (42)

1. 1-Adrenergic receptor subtypes. Molecular structure, function and signalling. Circ. Res. 78:1996;737-749.
2. 1-Adrenoceptors: subtypes, signaling and roles in health and disease. Arch. Med. Res. 31:1999;449-458.
3. 1-Adrenoceptors: function and phosphorylation. Eur. J. Pharmacol. 389:2000;1-12.
4. 1-Adrenergic receptors: new insights and directions. J. Pharmacol. Exp. Ther. 298:2001;403-410.
5. 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism. Proc. Natl. Acad. Sci. U. S. A. 82:1985;5651-5655.
6. 1b-adrenoceptors in Rat-1 fibroblasts. J. Biol. Chem. 272:1997;27330-27337.
7. 1B-adrenergic receptor. J. Biol. Chem. 272:1997;28712-28719.
8. 1b-adrenoceptors induced through activation of bradykinin B2 receptors. FEBS Lett. 422:1998;141-145.
9. 1b-adrenoceptor phosphorylation and function. Roles of Gi and phosphoinositide 3-kinase. Mol. Pharmacol. 57:2000;1027-1033.
10. 1b-adrenoceptors. Biochem. J. 350:2000;413-419.
11. 1-adrenergic receptor. Proc. Natl. Acad. Sci. U. S. A. 85:1988;7159-7163.
12. 1B-adrenergic receptor. J. Biol. Chem. 271:1996;5049-5058.
13. 1 adenosine receptor-mediated responses. Mol. Pharmacol. 56:1999;316-324.
14. García-Sáinz J.A., Romero-Avila M.T., Ruíz-Arriaga A., Ruíz-Puente J., Agundis C., Ortíz V., Isibasi A. Characterization and detoxification of an easily prepared acellular pertussis vaccine. Antigenic role of the A protomer of pertussis toxin. Vaccine. 10:1992;341-344.
15. 1a-adrenergic receptors. Functional aspects. J. Biol. Chem. 275:2000;6553-6559.
16. González A.L., Joly E. A simple procedure to increase efficiency of DEAE-dextran transfection of COS cells. Trends Genet. 11:1995;216-217.
17. Hara K., Yonezawa K., Sakaue H., Ando A., Kotani K., Kitamura T., Kitamura Y., Ueda H., Stephens L., Jackson T.R., Waterfield M.D., Kasuga M. L-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but nor for RAS activation in CHO cells. Proc. Natl. Acad. Sci. U. S. A. 91:1994;7415-7419.
18. Koch W.J., Hawes B.E., Inglese J., Luttrell L.M., Lefkowitz R.J. Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. J. Biol. Chem. 269:1994;6193-6197.
19. Wymann M.P., Pirola L. Structure and function of phosphoinositide 3-kinase. Biochim. Biophys. Acta. 1436:1998;127-150.
20. Vanhaesebroeck B., Waterfield M.D. Signaling by distinct classes of phosphoinositide 3-kinases. Exp. Cell Res. 253:1999;239-254.
21. Cantrell D.A. Phosphoinositide 3-kinase signalling pathways. J. Cell Sci. 114:2001;1439-1445.
22. Murga C., Laguinge L., Wetzker R., Cuadrado A., Gutkind J.S. Activation of AKT/protein kinase B by G protein-coupled receptors. A role for α and βγ subunits of heterotrimeric G proteins acting through phosphatidylinositol 3-kinase. J. Biol. Chem. 273:1998;19080-19085.
23. Murga C., Fukuhara S., Gutkind J.S. A novel role for phosphatidylinositol 3-kinase β in signaling from G protein-coupled receptors to Akt. J. Biol. Chem. 275:2000;12069-12073.
24. Kurose H., Maehama T., Okada T., Yamamoto T., Hoshino S.-I., Fukui Y., Ui M., Hazeki O., Katada T. Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110β is synergically activated by the βγ subunits of G proteins and phosphotyrosyl peptide. J. Biol. Chem. 272:1997;24252-24256.
25. Daub H., Weiss F.U., Wallasch C., Ullrich A. Role of transactivation of the EFG receptor in signalling by G-protein-coupled receptors. Nature. 379:1996;557-560.
26. Daub H., Wallash C., Lankenau A., Herrlich A., Ullrich A. Signal characteristics of G protein-transactivated EGF receptor. EMBO J. 16:1997;7032-7044.
27. Laffargue M., Raynal P., Yart A., Perez C., Wetzker R., Roche S., Payastre B., Chap H. An epidermal growth factor receptor/Gab 1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid. J. Biol. Chem. 274:1999;32835-32841.
28. Gohla A., Harhammer R., Schultz G. The G-protein G13 but not G12 mediated signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho. J. Biol. Chem. 273:1998;4653-4659.
29. Pierce K.L., Tohgo A., Ahn S., Field M.E., Luttrell L.M., Lefkowitz R.J. Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors. A co-culture system for identifying intermediated upstream and downstream of heparin-binding EGF shedding. J. Biol. Chem. 276:2001;23155-23160.
30. Prenzel N., Zwick E., Daub H., Leserer M., Relmar A., Wallasch C., Ullrich A. EGF receptor transactivation by G-protein coupled receptors requires metalloproteinase cleavage of proHB EGF. Nature. 402:1999;884-888.
31. Alessi D.R., Deak M., Casamayor A., Caudwell F.B., Morrice N., Norman D.G., Gaffney P., Reese C.B., MacDougall C.N., Harbison D., Ashworth A., Bownes M. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase. Curr. Biol. 7:1997;776-789.
32. Stephens L., Anderson K., Stokoe D., Erdjument Bromage H., Painter G.F., Holmes A.B., Gaffney P.R., Reese C.B., McCormick F., Tempst P., Coadwell J., Hawkins P.T. Protein kinase B kinases that mediate phosphatidylinositol 3, 4, 5-trisphosphate-dependent activation of protein kinase B. Science. 279:1998;710-714.
33. Le Good J.A., Ziegler W.H., Parekh D.B., Alessi D.R., Cohen P., Parker P.J. Protein kinase C isotypes controlled by phosphoinositide 3 kinase through the protein kinase PDK. Science. 281:1998;2042-2045.
34. Toker A. Protein kinases as mediators of phosphoinositide 3-kinase signaling. Mol. Pharmacol. 57:2000;652-658.
35. Newton A.C. Protein kinase C: structure, function and regulation. J. Biol. Chem. 270:1995;28495-28498.
36. 1b-adrenoceptor coimmunoprecipitation: effect of hormones and phorbol myristate acetate. Eur. J. Pharmacol. 419:2001;9-13.
37. Moolenaar W.H., Kanenburg O., Postma F.R., Zondag G.C. Lysophosphatidic acid: G-protein signalling and cellular responses. Curr. Opin. Cell Biol. 9:1997;168-173.
38. Huang M.-C., Graeler M., Shankar G., Spencer J., Goetzl E.J. Lysophospholipid mediators of immunity and neoplasia. Biochim. Biophys. Acta. 1582:2002;161-167.
39. Toews M.L., Edinger T.L., Tomberg D.J., Rennard S.I. Lysophosphatidic acid in airway function and disease. Biochim. Biophys. Acta. 1582:2002;240-250.
40. Lynch K.R. Lysophospholipid receptor nomenclature. Biochim. Biophys. Acta. 1582:2002;70-71.
41. Pages C., Simon M., Valet P., Saulmier-Blache J.S. Prostaglandins. 64:2001;1-10.
42. Pages G., Girard A., Jeanneton O., Barbe P., Wolf C., Lafontan M., Valet P., Saulmier-Blache J.S. Ann. N.Y. Acad. Sci. 905:2000;159-164.