-
1
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn EH: Switching and signaling at the telomere. Cell 2001, 106:661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
2
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW Harley CB, Bacchetti S: Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992, 11:1921-1929.
-
(1992)
EMBO J.
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
3
-
-
0037148276
-
Senescence: Does it all happen at the ends?
-
Stewart SA, Weinberg RA: Senescence: does it all happen at the ends? Oncogene 2002, 21:627-630.
-
(2002)
Oncogene
, vol.21
, pp. 627-630
-
-
Stewart, S.A.1
Weinberg, R.A.2
-
4
-
-
0031899814
-
Inactivation of p16 in human mammary epithelial cells by CpG island methylation
-
Foster SA, Wong DJ, Barrett MT, Galloway DA: Inactivation of p16 in human mammary epithelial cells by CpG island methylation. Mol Cell Biol 1998, 18:1793-1801.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 1793-1801
-
-
Foster, S.A.1
Wong, D.J.2
Barrett, M.T.3
Galloway, D.A.4
-
5
-
-
0035252089
-
Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
-
Romanov SR, Kozakiewicz BK, Holst CR, Stampfer MR, Haupt LM, Tlsty TD: Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 2001, 409:633-637.
-
(2001)
Nature
, vol.409
, pp. 633-637
-
-
Romanov, S.R.1
Kozakiewicz, B.K.2
Holst, C.R.3
Stampfer, M.R.4
Haupt, L.M.5
Tlsty, T.D.6
-
6
-
-
0032487675
-
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway D, Klingelhutz AJ: Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 1998, 396:84-88.
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.5
Klingelhutz, A.J.6
-
7
-
-
0035114576
-
Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
-
Ramirez RD, Morales CP, Herbert BS, Rohde JM, Passons C, Shay JW, Wright WE: Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev 2001, 15:398-403.
-
(2001)
Genes Dev.
, vol.15
, pp. 398-403
-
-
Ramirez, R.D.1
Morales, C.P.2
Herbert, B.S.3
Rohde, J.M.4
Passons, C.5
Shay, J.W.6
Wright, W.E.7
-
8
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco MA, Lee HW, hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW: Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 1997, 91:25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
9
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee HW, Blasco MA, Gottlieb GJ, Horner JW, Greider CW, DePinho RA: Essential role of mouse telomerase in highly proliferative organs. Nature 1998, 392:569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
Horner, J.W.4
Greider, C.W.5
DePinho, R.A.6
-
10
-
-
0033553516
-
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA: p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 1999, 97:527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottlieb, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
11
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
Gonzalez-Suarez E, Samper E, Flores JM, Blasco MA: Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet 2000, 26:114-117.
-
(2000)
Nat. Genet.
, vol.26
, pp. 114-117
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
12
-
-
0000146723
-
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse
-
Greenberg RA, Chin L, Femino A, Lee KH, Gottlieb GJ, Singer RH, Greider CW, DePinho RA: Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell 1999, 97:515-525.
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
Lee, K.H.4
Gottlieb, G.J.5
Singer, R.H.6
Greider, C.W.7
DePinho, R.A.8
-
13
-
-
0034978564
-
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
-
Rudolph KL, Millard M, Bosenberg MW, DePinho RA: Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat Genet 2001, 28:155-159.
-
(2001)
Nat. Genet.
, vol.28
, pp. 155-159
-
-
Rudolph, K.L.1
Millard, M.2
Bosenberg, M.W.3
DePinho, R.A.4
-
14
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA: Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 2000, 406:641-645.
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.L.3
Alson, S.4
Gottlieb, G.J.5
Chin, L.6
DePinho, R.A.7
-
15
-
-
0000839280
-
Telomere dysfunction provokes regional amplification and deletion in cancer genomes
-
O'Hagan RC, Chang S, Maser RS, Mohan R, Artandi SE, Chin L, DePinho RA: Telomere dysfunction provokes regional amplification and deletion in cancer genomes. Cancer Cell 2002, 2:149-155.
-
(2002)
Cancer Cell
, vol.2
, pp. 149-155
-
-
O'Hagan, R.C.1
Chang, S.2
Maser, R.S.3
Mohan, R.4
Artandi, S.E.5
Chin, L.6
DePinho, R.A.7
-
16
-
-
0033650397
-
Heterogeneous chromosomal aberrations in intraductal breast lesions adjacent to invasive carcinoma
-
Aubele M, Cummings M, Walsch A, Zitzelsberger H, Nahrig J, Hofler H, Werner M: Heterogeneous chromosomal aberrations in intraductal breast lesions adjacent to invasive carcinoma. Anal Cell Pathology 2000, 20:17-24.
-
(2000)
Anal. Cell Pathology
, vol.20
, pp. 17-24
-
-
Aubele, M.1
Cummings, M.2
Walsch, A.3
Zitzelsberger, H.4
Nahrig, J.5
Hofler, H.6
Werner, M.7
-
17
-
-
0034885252
-
Genetic changes in paired atypical and usual ductal hyperplasia of the breast by comparative genomic hybridization
-
Gong G, DeVries S, Chew KL, Cha I, Ljung BM, Waldman FM: Genetic changes in paired atypical and usual ductal hyperplasia of the breast by comparative genomic hybridization. Clin Cancer Res 2001, 7:2410-2414.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2410-2414
-
-
Gong, G.1
DeVries, S.2
Chew, K.L.3
Cha, I.4
Ljung, B.M.5
Waldman, F.M.6
-
18
-
-
0032980789
-
Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways
-
Buerger H, Otterbach F, Simon R, Poremba C, Diallo R, Decker T, Riethdorf L, Brinkschmidt C, Dockhorn-Dworniczak B, Boecker W: Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways. J Pathol 1999, 187:396-402.
-
(1999)
J. Pathol.
, vol.187
, pp. 396-402
-
-
Buerger, H.1
Otterbach, F.2
Simon, R.3
Poremba, C.4
Diallo, R.5
Decker, T.6
Riethdorf, L.7
Brinkschmidt, C.8
Dockhorn-Dworniczak, B.9
Boecker, W.10
-
19
-
-
0030838976
-
Genetic alterations in primary breast cancers and their metastases: Direct comparison using modified comparative genomic hybridization
-
Nishizaki T, DeVries S, Chew K, Goodson WH III, Ljung BM, Thor A, Waldman FM: Genetic alterations in primary breast cancers and their metastases: direct comparison using modified comparative genomic hybridization. Genes Chromosomes Cancer 1997, 19:267-272.
-
(1997)
Genes Chromosomes Cancer
, vol.19
, pp. 267-272
-
-
Nishizaki, T.1
DeVries, S.2
Chew, K.3
Goodson W.H. III4
Ljung, B.M.5
Thor, A.6
Waldman, F.M.7
-
20
-
-
0028303112
-
Reduction of telomeric length and c-erbB-2 gene amplification in human breast cancer, fibroadenoma, and gynecomastia. Relationship to histologic grade and clinical, parameters
-
Odagiri E, Kanada N, Jibiki K, Demura R, Aikawa E, Demura H: Reduction of telomeric length and c-erbB-2 gene amplification in human breast cancer, fibroadenoma, and gynecomastia. Relationship to histologic grade and clinical, parameters. Cancer 1994, 73:2978-2984.
-
(1994)
Cancer
, vol.73
, pp. 2978-2984
-
-
Odagiri, E.1
Kanada, N.2
Jibiki, K.3
Demura, R.4
Aikawa, E.5
Demura, H.6
-
21
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S: A survey of telomerase activity in human cancer. Eur J Cancer 1997, 33:787-791.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
22
-
-
0032924343
-
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
-
Morales CP, Holt SE, Ouellette M, Kaur KJ, Yan Y, Wilson KS, White MA, Wright WE, Shay JW: Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nat Genet 1999, 21:115-118.
-
(1999)
Nat. Genet.
, vol.21
, pp. 115-118
-
-
Morales, C.P.1
Holt, S.E.2
Ouellette, M.3
Kaur, K.J.4
Yan, Y.5
Wilson, K.S.6
White, M.A.7
Wright, W.E.8
Shay, J.W.9
-
23
-
-
0032923742
-
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
-
Jiang XR, Jimenez G, Chang E, Frolkis M, Kusler B, Sage M, Beeche M, Bodnar AB, Wahl GM, Tlsty TD, Chiu CP: Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 1999, 21:111-114.
-
(1999)
Nat. Genet.
, vol.21
, pp. 111-114
-
-
Jiang, X.R.1
Jimenez, G.2
Chang, E.3
Frolkis, M.4
Kusler, B.5
Sage, M.6
Beeche, M.7
Bodnar, A.B.8
Wahl, G.M.9
Tlsty, T.D.10
Chiu, C.P.11
-
24
-
-
0035836727
-
Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells
-
Stampfer MR, Garbe J, Levine G, Lichtsteiner S, Vasserot AP, Yaswen P: Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells. Proc Natl Acad Sci USA 2001, 98:4498-4503.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4498-4503
-
-
Stampfer, M.R.1
Garbe, J.2
Levine, G.3
Lichtsteiner, S.4
Vasserot, A.P.5
Yaswen, P.6
-
25
-
-
0037062454
-
Constitutive telomerase expression promotes mammary carcinomas in aging mice
-
Artandi SE, Alson S, Tietze MK, Sharpless N, Ye S, Greenberg R, Castrillion D, Horner J, Weiler S, Carrasco R, DePinho RA: Constitutive telomerase expression promotes mammary carcinomas in aging mice. Proc Natl Acad Sci USA 2002, 99: 8191-8196.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8191-8196
-
-
Artandi, S.E.1
Alson, S.2
Tietze, M.K.3
Sharpless, N.4
Ye, S.5
Greenberg, R.6
Castrillion, D.7
Horner, J.8
Weiler, S.9
Carrasco, R.10
DePinho, R.A.11
-
26
-
-
0035355340
-
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
-
Gonzalez-Suarez E, Samper E, Ramirez A, Flores JM, Martin-Caballero J, Jorcano JL, Blasco MA: Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J 2001, 20:2619-2630.
-
(2001)
EMBO J.
, vol.20
, pp. 2619-2630
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Ramirez, A.3
Flores, J.M.4
Martin-Caballero, J.5
Jorcano, J.L.6
Blasco, M.A.7
|