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Volumn 5, Issue 1, 2003, Pages 37-41

Complex roles for telomeres and telomerase in breast carcinogenesis

Author keywords

Breast cancer; Genomic instability; Mouse model; Telomerase; Telomere

Indexed keywords

DNA; PROTEIN P16; PROTEIN P53; TELOMERASE;

EID: 0038743066     PISSN: 14655411     EISSN: None     Source Type: Journal    
DOI: 10.1186/bcr553     Document Type: Article
Times cited : (19)

References (26)
  • 1
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn EH: Switching and signaling at the telomere. Cell 2001, 106:661-673.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 2
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW Harley CB, Bacchetti S: Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992, 11:1921-1929.
    • (1992) EMBO J. , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 3
    • 0037148276 scopus 로고    scopus 로고
    • Senescence: Does it all happen at the ends?
    • Stewart SA, Weinberg RA: Senescence: does it all happen at the ends? Oncogene 2002, 21:627-630.
    • (2002) Oncogene , vol.21 , pp. 627-630
    • Stewart, S.A.1    Weinberg, R.A.2
  • 4
    • 0031899814 scopus 로고    scopus 로고
    • Inactivation of p16 in human mammary epithelial cells by CpG island methylation
    • Foster SA, Wong DJ, Barrett MT, Galloway DA: Inactivation of p16 in human mammary epithelial cells by CpG island methylation. Mol Cell Biol 1998, 18:1793-1801.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 1793-1801
    • Foster, S.A.1    Wong, D.J.2    Barrett, M.T.3    Galloway, D.A.4
  • 5
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov SR, Kozakiewicz BK, Holst CR, Stampfer MR, Haupt LM, Tlsty TD: Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 2001, 409:633-637.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.R.1    Kozakiewicz, B.K.2    Holst, C.R.3    Stampfer, M.R.4    Haupt, L.M.5    Tlsty, T.D.6
  • 6
    • 0032487675 scopus 로고    scopus 로고
    • Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
    • Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway D, Klingelhutz AJ: Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 1998, 396:84-88.
    • (1998) Nature , vol.396 , pp. 84-88
    • Kiyono, T.1    Foster, S.A.2    Koop, J.I.3    McDougall, J.K.4    Galloway, D.5    Klingelhutz, A.J.6
  • 10
    • 0033553516 scopus 로고    scopus 로고
    • p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    • Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA: p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 1999, 97:527-538.
    • (1999) Cell , vol.97 , pp. 527-538
    • Chin, L.1    Artandi, S.E.2    Shen, Q.3    Tam, A.4    Lee, S.L.5    Gottlieb, G.J.6    Greider, C.W.7    DePinho, R.A.8
  • 11
    • 0343228751 scopus 로고    scopus 로고
    • Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
    • Gonzalez-Suarez E, Samper E, Flores JM, Blasco MA: Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet 2000, 26:114-117.
    • (2000) Nat. Genet. , vol.26 , pp. 114-117
    • Gonzalez-Suarez, E.1    Samper, E.2    Flores, J.M.3    Blasco, M.A.4
  • 13
    • 0034978564 scopus 로고    scopus 로고
    • Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
    • Rudolph KL, Millard M, Bosenberg MW, DePinho RA: Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat Genet 2001, 28:155-159.
    • (2001) Nat. Genet. , vol.28 , pp. 155-159
    • Rudolph, K.L.1    Millard, M.2    Bosenberg, M.W.3    DePinho, R.A.4
  • 14
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA: Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 2000, 406:641-645.
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.E.1    Chang, S.2    Lee, S.L.3    Alson, S.4    Gottlieb, G.J.5    Chin, L.6    DePinho, R.A.7
  • 17
    • 0034885252 scopus 로고    scopus 로고
    • Genetic changes in paired atypical and usual ductal hyperplasia of the breast by comparative genomic hybridization
    • Gong G, DeVries S, Chew KL, Cha I, Ljung BM, Waldman FM: Genetic changes in paired atypical and usual ductal hyperplasia of the breast by comparative genomic hybridization. Clin Cancer Res 2001, 7:2410-2414.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2410-2414
    • Gong, G.1    DeVries, S.2    Chew, K.L.3    Cha, I.4    Ljung, B.M.5    Waldman, F.M.6
  • 19
    • 0030838976 scopus 로고    scopus 로고
    • Genetic alterations in primary breast cancers and their metastases: Direct comparison using modified comparative genomic hybridization
    • Nishizaki T, DeVries S, Chew K, Goodson WH III, Ljung BM, Thor A, Waldman FM: Genetic alterations in primary breast cancers and their metastases: direct comparison using modified comparative genomic hybridization. Genes Chromosomes Cancer 1997, 19:267-272.
    • (1997) Genes Chromosomes Cancer , vol.19 , pp. 267-272
    • Nishizaki, T.1    DeVries, S.2    Chew, K.3    Goodson W.H. III4    Ljung, B.M.5    Thor, A.6    Waldman, F.M.7
  • 20
    • 0028303112 scopus 로고
    • Reduction of telomeric length and c-erbB-2 gene amplification in human breast cancer, fibroadenoma, and gynecomastia. Relationship to histologic grade and clinical, parameters
    • Odagiri E, Kanada N, Jibiki K, Demura R, Aikawa E, Demura H: Reduction of telomeric length and c-erbB-2 gene amplification in human breast cancer, fibroadenoma, and gynecomastia. Relationship to histologic grade and clinical, parameters. Cancer 1994, 73:2978-2984.
    • (1994) Cancer , vol.73 , pp. 2978-2984
    • Odagiri, E.1    Kanada, N.2    Jibiki, K.3    Demura, R.4    Aikawa, E.5    Demura, H.6
  • 21
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay JW, Bacchetti S: A survey of telomerase activity in human cancer. Eur J Cancer 1997, 33:787-791.
    • (1997) Eur. J. Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 24
    • 0035836727 scopus 로고    scopus 로고
    • Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells
    • Stampfer MR, Garbe J, Levine G, Lichtsteiner S, Vasserot AP, Yaswen P: Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells. Proc Natl Acad Sci USA 2001, 98:4498-4503.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4498-4503
    • Stampfer, M.R.1    Garbe, J.2    Levine, G.3    Lichtsteiner, S.4    Vasserot, A.P.5    Yaswen, P.6
  • 26
    • 0035355340 scopus 로고    scopus 로고
    • Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
    • Gonzalez-Suarez E, Samper E, Ramirez A, Flores JM, Martin-Caballero J, Jorcano JL, Blasco MA: Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J 2001, 20:2619-2630.
    • (2001) EMBO J. , vol.20 , pp. 2619-2630
    • Gonzalez-Suarez, E.1    Samper, E.2    Ramirez, A.3    Flores, J.M.4    Martin-Caballero, J.5    Jorcano, J.L.6    Blasco, M.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.