Characterization of the locomotor activity-inhibiting effect of nociceptin/orphanin FQ in mice

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 363, Issue 2, 2001, Pages 161-165

  Rizzi, A ^a   Bigoni, R ^a   Marzola, G ^a   Guerrini, Remo ^b   Salvadori, Severo ^b   Regoli, D ^a   Calo', G ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b Department of Pharmaceutical Sciences ^*  (Italy)

Author keywords

Mouse; NC receptor; Nociceptin orphanin FQ; Spontaneous locomotor activity; Nphe1 NC(1 13)NH2; Phe1 (CH2 NH)Gly2 NC(1 13)NH)2

Indexed keywords

MORPHINE; NALOXONE; NOCICEPTIN; NOCICEPTIN RECEPTOR; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; LOCOMOTION; MALE; MOUSE; NONHUMAN; PROTEIN ANALYSIS;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MORPHINE; MOTOR ACTIVITY; NALOXONE; NARCOTIC ANTAGONISTS; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; RECEPTORS, OPIOID;

EID: 0035094936     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000358     Document Type: Article

References (21)

1. Characterization of nociceptin receptors in the periphery: In vitro and in vivo studies
2. 2 N-terminal tetrapeptide and discovery of a nociceptin receptor antagonist
3. Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay
4. 2, a new selective nociceptin receptor antagonist
5. Pharmacology of nociceptin and its receptor - A novel therapeutic target
6. Nociceptin/orphanin FQ receptor ligands
7. Reverse physiology: Discovery of the novel neuropeptide, orphanin FQ/nociceptin
8. Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ
9. Nociceptin stimulates locomotion and exploratory behaviour in mice
10. Address and message sequences for the nociceptin receptor: A structure-activity study of nociceptin-(1-13)-peptide amide
11. 2 on nociceptin receptor mediated inhibition of cAMP formation in Chinese hamster ovary cells stably expressing the recombinant human nociceptin receptor
12. Intracerebroventricular injections in mice. Some methodological refinements
13. Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor
14. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
15. Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphanin FQ receptor
16. Association of aminopeptidase N and endopeptidase 24.15 inhibitors potentiates behavioral effects mediated by nociceptin/orphanin FQ in mice
17. Loss of antinociception induced by naloxone benzoylhydrazone in nociceptin receptor-knockout mice
18. Pharmacological characterization of the nociceptin receptor mediating hyperphagia: Identification of a selective antagonist
19. Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor
20. [Nphe(1)]nociceptin-(1-13)-NH(2) antagonizes nociceptin effects in the mouse colon
21. Modulation of 5-HT efflux from rat cortical synaptosomes by opioids and nociceptin