-
1
-
-
0030786717
-
Prion research: The next frontiers
-
Aguzzi, A., and C. Weissmann. 1997. Prion research: the next frontiers. Nature 389:795-798.
-
(1997)
Nature
, vol.389
, pp. 795-798
-
-
Aguzzi, A.1
Weissmann, C.2
-
2
-
-
0025314573
-
Presence of mitochondrial D-loop DNA in scrapie-infected brain preparations enriched for prion protein
-
Aiken, J.M., J.L. Williamson, M. Borchardt, et al. 1990. Presence of mitochondrial D-loop DNA in scrapie-infected brain preparations enriched for prion protein. J. Virol. 64:3265-3268.
-
(1990)
J. Virol.
, vol.64
, pp. 3265-3268
-
-
Aiken, J.M.1
Williamson, J.L.2
Borchardt, M.3
-
3
-
-
0034798246
-
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
-
Aucouturier, P., F. Geissmann, D. Damotte, et al. 2001. Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J. Clin. Invest. 703-708.
-
(2001)
J. Clin. Invest.
, pp. 703-708
-
-
Aucouturier, P.1
Geissmann, F.2
Damotte, D.3
-
4
-
-
0345188622
-
Microglial activation varies in different models of Creutzfeldt-Jakob disease
-
Baker, C., Z.Y. Lu, I. Zaitsev, et al. 1999. Microglial activation varies in different models of Creutzfeldt-Jakob disease. J. Virol. 73:5089-5097.
-
(1999)
J. Virol.
, vol.73
, pp. 5089-5097
-
-
Baker, C.1
Lu, Z.Y.2
Zaitsev, I.3
-
5
-
-
0037457875
-
Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease
-
Baker, C., and L. Manuelidis. 2003. Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease. Proc. Natl. Acad. Sci. USA 100:675-679.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 675-679
-
-
Baker, C.1
Manuelidis, L.2
-
6
-
-
0036838213
-
Microglia from CJD brain are infectious and show specific mRNA activation profiles
-
Baker, C.A., D. Martin, and L. Manuelidis. 2002. Microglia from CJD brain are infectious and show specific mRNA activation profiles. J. Virol. 10905-10913.
-
(2002)
J. Virol.
, pp. 10905-10913
-
-
Baker, C.A.1
Martin, D.2
Manuelidis, L.3
-
7
-
-
0035903461
-
Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers
-
Barron, R., V. Thomson, E. Jamieson, et al. 2001. Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers. EMBO J. 17:5070-5078.
-
(2001)
EMBO J.
, vol.17
, pp. 5070-5078
-
-
Barron, R.1
Thomson, V.2
Jamieson, E.3
-
8
-
-
0036184403
-
Strain characterization of natural sheep scrapie and comparison with BSE
-
Bruce, M., A. Boyle, S. Cousens, et al. 2002. Strain characterization of natural sheep scrapie and comparison with BSE. J. Gen. Virol. 83:695-704.
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 695-704
-
-
Bruce, M.1
Boyle, A.2
Cousens, S.3
-
9
-
-
0023205075
-
Biological evidence that scrapie has an independent genome
-
Bruce, M.E., and A.G. Dickinson. 1987. Biological evidence that scrapie has an independent genome. J. Gen. Virol. 68:79-89.
-
(1987)
J. Gen. Virol.
, vol.68
, pp. 79-89
-
-
Bruce, M.E.1
Dickinson, A.G.2
-
10
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Büeler, H., A. Aguzzi, A. Sailer, et al. 1993. Mice devoid of PrP are resistant to scrapie. Cell 73:1339-1347.
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Büeler, H.1
Aguzzi, A.2
Sailer, A.3
-
11
-
-
0031023679
-
Scrapie strains retain their distinctive characteristics following passages of homogenates from different brain regions and spleen
-
Carp, R., H. Meeker, and E. Sersen. 1997. Scrapie strains retain their distinctive characteristics following passages of homogenates from different brain regions and spleen. J. Gen. Virol. 78:283-290.
-
(1997)
J. Gen. Virol.
, vol.78
, pp. 283-290
-
-
Carp, R.1
Meeker, H.2
Sersen, E.3
-
12
-
-
0345716276
-
Highly infectious purified preparations of disease-specific amyloid of transmissible spongiform encephalopathies are not devoid of nucleic acids of viral size
-
Diringer, H., M. Beekes, M. Ozel, et al. 1997. Highly infectious purified preparations of disease-specific amyloid of transmissible spongiform encephalopathies are not devoid of nucleic acids of viral size. Intervirology 40:238-246.
-
(1997)
Intervirology
, vol.40
, pp. 238-246
-
-
Diringer, H.1
Beekes, M.2
Ozel, M.3
-
13
-
-
0021036329
-
Scrapie infectivity, fibrils and low molecular weight protein
-
Diringer, H., H. Gelderblom, H. Hilmert, et al. 1983. Scrapie infectivity, fibrils and low molecular weight protein. Nature 306:476-478.
-
(1983)
Nature
, vol.306
, pp. 476-478
-
-
Diringer, H.1
Gelderblom, H.2
Hilmert, H.3
-
14
-
-
0029844811
-
Visualization of viral candidate cDNAs in infectious brain fractions from Creutzfeldt-Jakob disease by representational difference analysis
-
Dron, M., and L. Manuelidis. 1996. Visualization of viral candidate cDNAs in infectious brain fractions from Creutzfeldt-Jakob disease by representational difference analysis. J. Neurovirol. 2:240-248.
-
(1996)
J. Neurovirol.
, vol.2
, pp. 240-248
-
-
Dron, M.1
Manuelidis, L.2
-
15
-
-
0014051249
-
Pathogenesis of scrapie virus infection in the mouse
-
Eklund, C.M., R.C. Kennedy, and W.J. Hadlow. 1967. Pathogenesis of scrapie virus infection in the mouse. J. Infect. Dis. 117:15-22.
-
(1967)
J. Infect. Dis.
, vol.117
, pp. 15-22
-
-
Eklund, C.M.1
Kennedy, R.C.2
Hadlow, W.J.3
-
16
-
-
0029863648
-
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
-
Fischer, M., T. Rulicke, A. Raeber, et al. 1996. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J. 15:1255-1264.
-
(1996)
EMBO J.
, vol.15
, pp. 1255-1264
-
-
Fischer, M.1
Rulicke, T.2
Raeber, A.3
-
17
-
-
0033576323
-
Transmissible and genetic prion diseases share a common pathway of neurodegeneration
-
Hegde, R., P. Tremblay, D. Groth, et al. 1999. Transmissible and genetic prion diseases share a common pathway of neurodegeneration. Nature 402:822-826.
-
(1999)
Nature
, vol.402
, pp. 822-826
-
-
Hegde, R.1
Tremblay, P.2
Groth, D.3
-
18
-
-
0033573778
-
Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples
-
Hill, A., R. Butterworth, S. Joiner, et al. 1999. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 353:183-189.
-
(1999)
Lancet
, vol.353
, pp. 183-189
-
-
Hill, A.1
Butterworth, R.2
Joiner, S.3
-
19
-
-
0038657071
-
Transmission of BSE by blood transfusion in sheep
-
Houston, F., J. Foster, A. Chong, et al. 2000. Transmission of BSE by blood transfusion in sheep. Lancet 16:955-956.
-
(2000)
Lancet
, vol.16
, pp. 955-956
-
-
Houston, F.1
Foster, J.2
Chong, A.3
-
20
-
-
0030985542
-
Is scrapie solely a genetic disease?
-
Hunter, N., D. Cairns, J. Foster, et al. 1997. Is scrapie solely a genetic disease? Nature 386:137.
-
(1997)
Nature
, vol.386
, pp. 137
-
-
Hunter, N.1
Cairns, D.2
Foster, J.3
-
21
-
-
0027468779
-
Cloning the differences between two complex genomes
-
Lisitsyn, N., N. Lisitsyn, and M. Wigler. 1993. Cloning the differences between two complex genomes. Science 259:946-951.
-
(1993)
Science
, vol.259
, pp. 946-951
-
-
Lisitsyn, N.1
Lisitsyn, N.2
Wigler, M.3
-
22
-
-
0018099217
-
Viremia in experimental Creutzfeldt-Jakob disease
-
Manuelidis, E.E., E.J. Gorgacz, and L. Manuelidis. 1978. Viremia in experimental Creutzfeldt-Jakob disease. Science 200:1069-1071.
-
(1978)
Science
, vol.200
, pp. 1069-1071
-
-
Manuelidis, E.E.1
Gorgacz, E.J.2
Manuelidis, L.3
-
23
-
-
0031432869
-
Beneath the emperor's clothes: The body of data in scrapie and CJD
-
Manuelidis, L. 1997. Beneath the emperor's clothes: the body of data in scrapie and CJD. Ann. Inst. Pasteur 8:311-326.
-
(1997)
Ann. Inst. Pasteur
, vol.8
, pp. 311-326
-
-
Manuelidis, L.1
-
24
-
-
0031059831
-
Decontamination of Creutzfeldt-Jakob disease and other transmissible agents
-
Manuelidis, L. 1997. Decontamination of Creutzfeldt-Jakob disease and other transmissible agents. J. Neurovirol. 3:62-65.
-
(1997)
J. Neurovirol.
, vol.3
, pp. 62-65
-
-
Manuelidis, L.1
-
25
-
-
0028235039
-
Dementias, neurodegeneration, and viral mechanisms of disease from the perspective of human transmissible encephalopathies
-
Manuelidis, L. 1994. Dementias, neurodegeneration, and viral mechanisms of disease from the perspective of human transmissible encephalopathies. Ann. N.Y. Acad. Sci. 724:259-281.
-
(1994)
Ann. N.Y. Acad. Sci.
, vol.724
, pp. 259-281
-
-
Manuelidis, L.1
-
26
-
-
0027968896
-
The dimensions of Creutzfeldt-Jakob disease
-
Manuelidis, L. 1994. The dimensions of Creutzfeldt-Jakob disease. Transfusion 34:915-928.
-
(1994)
Transfusion
, vol.34
, pp. 915-928
-
-
Manuelidis, L.1
-
27
-
-
0034704239
-
Penny wise, pound foolish - A retrospective
-
Manuelidis, L. 2000. Penny wise, pound foolish - a retrospective. Science 290:2257.
-
(2000)
Science
, vol.290
, pp. 2257
-
-
Manuelidis, L.1
-
28
-
-
0032478072
-
Vaccination with an attenuated CJD strain prevents expression of a virulent agent
-
Manuelidis, L. 1998. Vaccination with an attenuated CJD strain prevents expression of a virulent agent. Proc. Natl. Acad. Sci. USA 95:2520-2525.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2520-2525
-
-
Manuelidis, L.1
-
29
-
-
0029866901
-
Infectivity and host responses in Creutzfeldt-Jakob disease
-
Manuelidis, L., and W. Fritch. 1996. Infectivity and host responses in Creutzfeldt-Jakob disease. Virology 215:46-59.
-
(1996)
Virology
, vol.215
, pp. 46-59
-
-
Manuelidis, L.1
Fritch, W.2
-
30
-
-
0030758270
-
Evolution of a strain of CJD that induces BSE-like plaques
-
Manuelidis, L., W. Fritch, and Y.G. Xi. 1997. Evolution of a strain of CJD that induces BSE-like plaques. Science 277:94-98.
-
(1997)
Science
, vol.277
, pp. 94-98
-
-
Manuelidis, L.1
Fritch, W.2
Xi, Y.G.3
-
31
-
-
0034602565
-
Attenuated Creutzfeldt-Jakob disease agents can hide more virulent infections
-
Manuelidis, L., and Z.Y. Lu. 2000. Attenuated Creutzfeldt-Jakob disease agents can hide more virulent infections. Neurosci. Lett. 293:163-166.
-
(2000)
Neurosci. Lett.
, vol.293
, pp. 163-166
-
-
Manuelidis, L.1
Lu, Z.Y.2
-
32
-
-
0038302903
-
Virus-like interference in the latency and prevention of Creutzfeldt-Jakob disease
-
a. Manuelidis, L., and B.Y. Lu. 2003. Virus-like interference in the latency and prevention of Creutzfeldt-Jakob disease. Proc. Natl. Acad. Sci. USA 100:5360-5365.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5360-5365
-
-
Manuelidis, L.1
Lu, B.Y.2
-
33
-
-
0023775668
-
Potential involvement of retroviral elements in human dementias
-
Manuelidis, L., G. Murdoch, and E. Manuelidis. 1988. Potential involvement of retroviral elements in human dementias. Ciba Found. Symp. 135:117-134.
-
(1988)
Ciba Found. Symp.
, vol.135
, pp. 117-134
-
-
Manuelidis, L.1
Murdoch, G.2
Manuelidis, E.3
-
34
-
-
0029035284
-
Viral particles are required for infection in neurodegenerative Creutzfeldt-Jakob disease
-
Manuelidis, L., T. Sklaviadis, A. Akowitz, et al. 1995. Viral particles are required for infection in neurodegenerative Creutzfeldt-Jakob disease. Proc. Natl. Acad. Sci. USA 92:5124-5128.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5124-5128
-
-
Manuelidis, L.1
Sklaviadis, T.2
Akowitz, A.3
-
35
-
-
0023282354
-
Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease
-
Manuelidis, L., T. Sklaviadis, and E.E. Manuelidis. 1987. Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease. EMBO J. 6:341-347.
-
(1987)
EMBO J.
, vol.6
, pp. 341-347
-
-
Manuelidis, L.1
Sklaviadis, T.2
Manuelidis, E.E.3
-
36
-
-
0033856794
-
Follicular dendritic cells and the dissemination of Creutzfeldt-Jakob disease
-
Manuelidis, L., I. Zaitsev, P. Koni, et al. 2000. Follicular dendritic cells and the dissemination of Creutzfeldt-Jakob disease. J. Virol. 74:8614-8622.
-
(2000)
J. Virol.
, vol.74
, pp. 8614-8622
-
-
Manuelidis, L.1
Zaitsev, I.2
Koni, P.3
-
37
-
-
0021023167
-
A protease-resistant protein is a structural component of the scrapie prion
-
McKinley, M.P., D.C. Bolton, and S.B. Prusiner. 1983. A protease-resistant protein is a structural component of the scrapie prion. Cell 35:57-62.
-
(1983)
Cell
, vol.35
, pp. 57-62
-
-
McKinley, M.P.1
Bolton, D.C.2
Prusiner, S.B.3
-
38
-
-
0021036327
-
Scrapie-associated fibrils in Creutzfeldt-Jakob disease
-
Merz, P.A., R.A. Somerville, H.M. Wisniewski, et al. 1983. Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature 306:474-476.
-
(1983)
Nature
, vol.306
, pp. 474-476
-
-
Merz, P.A.1
Somerville, R.A.2
Wisniewski, H.M.3
-
39
-
-
0034686002
-
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
-
Montrasio, F., R. Frigg, M. Glatzel, et al. 2000. Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science 288:1257-1259.
-
(2000)
Science
, vol.288
, pp. 1257-1259
-
-
Montrasio, F.1
Frigg, R.2
Glatzel, M.3
-
40
-
-
0025209915
-
Potential retroviral RNAs in Creutzfeldt-Jakob disease
-
Murdoch, G., T. Sklaviadis, E.E. Manuelidis, et al. 1990. Potential retroviral RNAs in Creutzfeldt-Jakob disease. J. Virol. 64:1477-1486.
-
(1990)
J. Virol.
, vol.64
, pp. 1477-1486
-
-
Murdoch, G.1
Sklaviadis, T.2
Manuelidis, E.E.3
-
41
-
-
0033988236
-
Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein
-
Nishida, N., D.A. Harris, D. Vilette, et al. 2000. Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein. J. Virol. 74:320-325.
-
(2000)
J. Virol.
, vol.74
, pp. 320-325
-
-
Nishida, N.1
Harris, D.A.2
Vilette, D.3
-
42
-
-
0023757760
-
Search for a scrapie-specific nucleic acid: A progress report
-
Oesch, B., D.F. Groth, S.B. Prusiner, et al. 1988. Search for a scrapie-specific nucleic acid: a progress report. Ciba Found. Symp. 135:209-217.
-
(1988)
Ciba Found. Symp.
, vol.135
, pp. 209-217
-
-
Oesch, B.1
Groth, D.F.2
Prusiner, S.B.3
-
44
-
-
0025910229
-
Molecular biology of prion diseases
-
Prusiner, S.B. 1991. Molecular biology of prion diseases. Science 252:1515-1522.
-
(1991)
Science
, vol.252
, pp. 1515-1522
-
-
Prusiner, S.B.1
-
45
-
-
2942616756
-
Blood-borne transit of CJD from brain to gut at early stages of infection
-
Radebold, K., M. Chernyak, D. Martin, et al. 2001. Blood-borne transit of CJD from brain to gut at early stages of infection. BMC Infect. Dis. 1:20-25.
-
(2001)
BMC Infect. Dis.
, vol.1
, pp. 20-25
-
-
Radebold, K.1
Chernyak, M.2
Martin, D.3
-
46
-
-
0030026759
-
Disruption of prion rods generates 10-nm spherical particles having high a-helical content and lacking scrapie infectivity
-
Riesner, D., K. Kellings, K. Post, et al. 1996. Disruption of prion rods generates 10-nm spherical particles having high a-helical content and lacking scrapie infectivity. J. Virol. 70:1714-1722.
-
(1996)
J. Virol.
, vol.70
, pp. 1714-1722
-
-
Riesner, D.1
Kellings, K.2
Post, K.3
-
47
-
-
0035859102
-
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
-
Saborio, G., B. Permanne, and C. Soto. 2001. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411:810-813.
-
(2001)
Nature
, vol.411
, pp. 810-813
-
-
Saborio, G.1
Permanne, B.2
Soto, C.3
-
48
-
-
0035957944
-
Reconstitution of prion infectivity from solubilized protease-resistant PrP and nonprotein components of prion rods
-
Shaked, G., Z. Meiner, I. Avraham, et al. 2001. Reconstitution of prion infectivity from solubilized protease-resistant PrP and nonprotein components of prion rods. J. Biol. Chem. 17:1432-1438.
-
(2001)
J. Biol. Chem.
, vol.17
, pp. 1432-1438
-
-
Shaked, G.1
Meiner, Z.2
Avraham, I.3
-
49
-
-
0035979189
-
Neuroinvasion by a Creutzfeldt-Jakob disease agent in the absence of B cells and follicular dendritic cells
-
Shlomchik, M., K. Radebold, N. Duclos, et al. 2001. Neuroinvasion by a Creutzfeldt-Jakob disease agent in the absence of B cells and follicular dendritic cells. Proc. Natl. Acad. Sci. USA 98:9289-9294.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9289-9294
-
-
Shlomchik, M.1
Radebold, K.2
Duclos, N.3
-
50
-
-
0025046363
-
Nuclease treatment results in high specific purification of Creutzfeldt-Jakob disease infectivity with a density characteristic of nucleic acid-protein complexes
-
Sklaviadis, T., A. Akowitz, E.E. Manuelidis, et al. 1990. Nuclease treatment results in high specific purification of Creutzfeldt-Jakob disease infectivity with a density characteristic of nucleic acid-protein complexes. Arch. Virol. 112:215-229.
-
(1990)
Arch. Virol.
, vol.112
, pp. 215-229
-
-
Sklaviadis, T.1
Akowitz, A.2
Manuelidis, E.E.3
-
51
-
-
0030019508
-
The association between PrP and infectivity in scrapie and BSE infected mouse brain
-
Somerville, R.A., and A. Dunn, 1996. The association between PrP and infectivity in scrapie and BSE infected mouse brain. Arch Virol. 14:275-289.
-
(1996)
Arch. Virol.
, vol.14
, pp. 275-289
-
-
Somerville, R.A.1
Dunn, A.2
-
52
-
-
0029132280
-
First experimental transmission of fatal familial insomnia
-
Tateishi, J., P. Brown, T. Kitamoto, et al. 1995. First experimental transmission of fatal familial insomnia. Nature 376:434-435.
-
(1995)
Nature
, vol.376
, pp. 434-435
-
-
Tateishi, J.1
Brown, P.2
Kitamoto, T.3
-
53
-
-
0028882424
-
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
-
Telling, G.C., M. Scott, J. Mastrianni, et al. 1995. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 83:79-90.
-
(1995)
Cell
, vol.83
, pp. 79-90
-
-
Telling, G.C.1
Scott, M.2
Mastrianni, J.3
-
54
-
-
0026600866
-
Amphotericin B treatment dissociates in vivo replication of the scrapie agent from PrP accumulation
-
Xi, Y.G., A. Ingrosso, A. Ladogana, et al. 1992. Amphotericin B treatment dissociates in vivo replication of the scrapie agent from PrP accumulation. Nature 356:598-601.
-
(1992)
Nature
, vol.356
, pp. 598-601
-
-
Xi, Y.G.1
Ingrosso, A.2
Ladogana, A.3
|