Changes in gene expression induced by H2O2 in cardiac myocytes

Biochemical and Biophysical Research Communications

Volumn 307, Issue 2, 2003, Pages 416-421

  Kemp, Timothy J ^a   Causton, Helen C ^a   Clerk, Angela ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiac myocytes; Gene expression; Heat shock protein; Heme oxygenase; Microarrays; Oxidative stress; P21Cip1 Waf1; Syndecan

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEME OXYGENASE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; INTEGRIN; PROTEIN P21; SYNDECAN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; GENE; GENE EXPRESSION; HEART MUSCLE CELL; HEART VENTRICLE; INTRACELLULAR SPACE; MULTIGENE FAMILY; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNINDEXED SEQUENCE; UPREGULATION;

EID: 0038690249     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)01215-4     Document Type: Article

References (23)

1. Vanden Hoek T.L., Li C., Shao Z., Schumacker P.T., Becker L.B. Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion. J. Mol. Cell. Cardiol. 29:1997;2571-2583.
2. Ferrari R., Agnoletti L., Comini L., Gaia G., Bachetti T., Cargnoni A., Ceconi C., Curello S., Visioli O. Oxidative stress during myocardial ischaemia and heart failure. Eur. Heart J. 19(Suppl. B):1998;B2-B11.
3. Ide T., Tsutsui H., Kinugawa S., Suematsu N., Hayashidani S., Ichikawa K., Utsumi H., Macida Y., Egashira K., Takeshita A. Direct evidence for increased hydroxyl radicals originating from superoxide in the failing human myocardium. Circ. Res. 86:2000;152-157.
4. Boveris A., Oshino N., Chance B. The cellular production of hydrogen peroxide. Biochem. J. 128:1972;617-630.
5. Sawyer D.B., Siwik D.A., Xiao L., Pimental D.R., Singh K., Colucci W.S. Role of oxidative stress in myocardial hypertrophy and failure. J. Mol. Cell. Cardiol. 34:2002;379-388.
6. Ide T., Tsutsui H., Kinugawa S., Utsumi H., Kang D., Hattori N., Uchida K., Arimura K., Egashira K., Takeshita A. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ. Res. 85:1999;357-363.
7. Cook S.A., Sugden P.H., Clerk A. Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. Circ. Res. 85:1999;940-949.
8. von Harsdorf R., Li P.-F., Dietz R. Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation. 99:1999;2934-2941.
9. Kang P.M., Haunstetter A., Aoki H., Usheva A., Izumo S. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ. Res. 87:2000;118-125.
10. Clerk A., Cole S.M., Cullingford T.E., Harrison J.G., Jormakka M., Valks D.M. Regulation of cardiac myocyte cell death. Pharm. Ther. 97:2003;223-261.
11. Ytrehus K., Walsh R.S., Richards S.C., Downey J.M. Hydrogen peroxide as a protective agent during reperfusion. A study in the isolated perfused rabbit heart subjected to regional ischemia. Cardiovasc. Res. 30:1995;1033-1037.
12. 2-induced cardiac dysfunction. Free Radic. Res. 29:1998;235-245.
13. Bogoyevitch M.A., Clerk A., Sugden P.H. Activation of the mitogen-activated protein kinase cascade by pertussis toxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes. Biochem. J. 309:1995;437-443.
14. Kemp T.J., Sadusky T.J., Saltisi F., Carey N., Moss J., Yang S.Y., Sassoon D.A., Goldspink G., Coulton G.R. Identification of Ankrd2, a novel muscle gene coding for a stretch-responsive ankyrin-repeat protein. Genomics. 66:2000;229-241.
15. Clerk A., Kemp T.J., Harrison J.G., Mullen A.J., Barton P.J., Sugden P.H. Upregulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient upregulation of c-Jun protein. Biochem. J. 368:2002;101-110.
16. 1-phase progression. Genes Dev. 13:1999;1501-1512.
17. Coqueret O. New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol. 13:2003;65-70.
18. Woods A. Syndecans: transmembrane modulators of adhesion and matrix assembly. J. Clin. Invest. 107:2001;935-941.
19. Benjamin I.J., McMillan D.R. Stress (heat shock) proteins. Molecular chaperones in cardiovascular biology and disease. Circ. Res. 83:1998;117-132.
20. Kukreja R.C., Kontos M.C., Loesser K.E., Batra S.K., Qian Y.Z., Gbur C.J., Naseem S.A., Jesse R.L., Hess M.L. Oxidant stress increases heat shock protein 70 mRNA in isolated perfused rat heart. Am. J. Physiol. 267:1994;H2213-H2219.
21. Yet S.F., Tian R., Layne M.D., Wang Z.Y., Maemura K., Solovyeva M., Ith B., Melo L.G., Zhang L., Ingwall J.S., Dzau V.J., Lee M.E., Perrella M.A. Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice. Circ. Res. 89:2001;168-173.
22. Inguaggiato P., GonzalezMichaca L., Groatt A.J., Haggard J.J., Alam J., Nath K.A. Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis. Kidney Int. 60:2001;2181-2191.
23. Cip1 expression. J. Biol. Chem. 277:2002;13761-13770.