Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein

Biochemical Journal

Volumn 368, Issue 1, 2002, Pages 101-110

  Clerk, Angela ^a,b   Kemp, Timothy J ^a   Harrison, Joanne G ^a   Mullen, Anthony J ^a   Barton, Paul J R ^a   Sugden, Peter H ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Heart; Immediate early gene; Mitogen activated protein kinase

Indexed keywords

DEGRADATION; ENZYMES; GENES; RNA;

PHOSPHORYLATION; TRANSCRIPTION;

BIOCHEMISTRY;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENDOTHELIN 1; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHENYLEPHRINE; PROTEIN C JUN; PROTEIN KINASE C INHIBITOR; SORBITOL; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE CONTROL; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; IMMEDIATE EARLY GENE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RAT; TRANSCRIPTION REGULATION;

ANIMALS; ENDOTHELIN-1; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; OSMOTIC PRESSURE; PHENYLEPHRINE; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; UP-REGULATION;

ANIMALIA; JANUS;

EID: 0037113124     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021083     Document Type: Article

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