p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB

EMBO Journal

Volumn 22, Issue 11, 2003, Pages 2810-2820

  Crighton, Diane ^c   Woiwode, Annette ^b   Zhang, Cheng ^b   Mandavia, Nihar ^b   Morton, Jennifer P ^c   Warnock, Lorna J ^a   Milner, Jo ^a   White, Robert J ^c   Johnson, Deborah L ^b  

^a UNIVERSITY OF YORK   (United Kingdom)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c NONE

Author keywords

p53; RNA polymerase III; TBPF; TFIIIB; Transcription

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; PROTEIN P53; TATA BINDING PROTEIN;

APOPTOSIS; ARTICLE; COMPLEX FORMATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR DOWN REGULATION; RECEPTOR OCCUPANCY; RNA TRANSLATION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; BINDING SITES; DNA, NEOPLASM; GENE EXPRESSION; GENES, P53; HELA CELLS; HUMANS; MICE; MICE, KNOCKOUT; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RNA POLYMERASE III; SACCHAROMYCES CEREVISIAE PROTEINS; TATA-BINDING PROTEIN ASSOCIATED FACTORS; TATA-BOX BINDING PROTEIN; TRANSCRIPTION FACTOR TFIIIB; TRANSCRIPTION FACTORS, TFIII; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0038521256     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg265     Document Type: Article

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