Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription

Molecular and Cellular Biology

Volumn 20, Issue 24, 2000, Pages 9192-9202

  Sutcliffe, J E ^a   Brown, T R P ^a   Allison, S J ^a   Scott, P H ^a   White, R J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; HISTONE DEACETYLASE; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE REPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL LINE; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; MICE; MODELS, GENETIC; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA PROTEIN; RNA POLYMERASE III; RNA, SMALL NUCLEAR; TRANSCRIPTION FACTOR TFIIIB; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFIII; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA;

EID: 0034459686     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.24.9192-9202.2000     Document Type: Article

References (65)

1. Regulation of a TATA-binding protein-associated factor during cellular differentiation
2. Common and unique transcription factor requirements of human U1 and U6 snRNA genes
3. Retinoblastoma protein meets chromatin
4. Retinoblastoma protein recruits histone deacetylase to repress transcription
5. p53 is a general repressor of RNA polymerase III transcription
6. Enhanced B2 transcription in simian virus 40-transformed cells is mediated through the formation of RNA polymerase III transcription complexes on previously inactive genes
7. Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product
8. RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2
9. Ordering promoter binding of class III transcription factors TFIIIC1 and TFIIIC2
10. Separation of TFIIIC into two functional components by sequence specific DNA affinity chromatography
11. The regulation of E2F by pRB-family proteins
12. Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth
13. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
14. Regulation of cell proliferation by the E2F transcription factors
15. The retinoblastoma protein: A master regulator of cell cycle, differentiation and apoptosis
16. Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
17. The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity
18. pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes
19. Acetylation of general transcription factors by histone acetyltransferases
20. The gene complementing a temperature-sensitive cell cycle mutant of BHK cells is the human homologue of the yeast RPC53 gene, which encodes a subunit of RNA polymerase C (III)
21. The BN51 protein is a polymerase (Pol)-specific subunit of RNA Pol III which reveals a link between Pol III transcription and pre-rRNA processing
22. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
23. S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors
24. A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding
25. Sin meets NuRD and other tails of repression
26. Human TFIIIC relieves chromatin-mediated repression of RNA polymerase III transcription and contains an intrinsic histone acetyltransferase activity
27. Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC
28. Mechanistic analysis of RNA polymerase III regulation by the retinoblastoma protein
29. Activation of RNA polymerase III transcription in cells transformed by simian virus 40
30. A positive role for histone acetylation in transcription factor access to nucleosomal DNA
31. A 7 bp mutation converts a human RNA polymerase II snRNA promoter into an RNA polymerase III promoter
32. The cloned RNA polymerase II transcription factor IID selects RNA polymerase III to transcribe the human U6 gene in vitro
33. A TBP complex essential for transcription from TATA-less but not TATA-containing RNA polymerase III promoters is part of the TFIIIB fraction
34. Rb interacts with histone deacetylase to repress transcription
35. Retinoblastoma protein represses transcription by recruiting a histone deacetylase
36. RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB
37. The retinoblastoma gene family: Cousins with overlapping interests
38. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
39. Transcription by RNA polymerases I and III
40. Regional specialization in human nuclei: Visualization of discrete sites of transcription by RNA polymerase III
41. Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis
42. Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein
43. Adenovirus type 2 preferentially stimulates polymerase III transcription of Alu elements by relieving repression: A potential role for chromatin
44. DNA damage activates p53 through a phosphorylation-acetylation cascade
45. Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
46. RNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130
47. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
48. RB kinases and RB-binding proteins: New points of view
49. Functional interchangeability of TFIIIB components from yeast and human cells in vitro
50. Physical separation of two different forms of human TFIIIB active in the transcription of the U6 or the VAI gene in vitro
51. Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III
52. Histone acetylation: Influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression
53. Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein
54. Identification of transcription factors required for the expression of mammalian U6 genes in vitro
55. Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition
56. Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains
57. The retinoblastoma protein and cell cycle control
58. Regulation of RNA polymerases I and III by the retinoblastoma protein: A mechanism for growth control?
59. Mitotic regulation of a TATA-binding-protein-containing complex
60. Regulation of RNA polymerase III transcription in response to F9 embryonal carcinoma stem cell differentiation
61. Repression of RNA polymerase III transcription by the retinoblastoma protein
62. Oncogenic point mutations in the human retinoblastoma gene: Their application to genetic counseling
63. Potent and specific inhibition of histone deacetylase both in vitro and in vivo by trichostatin A
64. Resolution of human transcription factor TFIIIC into two functional components