Scabrous and Gp150 are endosomal proteins that regulate Notch activity

Development

Volumn 130, Issue 13, 2003, Pages 2819-2827

  Li, Yanxia ^a   Fetchko, Michael ^b   Lai, Zhi Chun ^b   Baker, Nicholas E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Drosophila eye; Endosome; Gp150; Notch; Scabrous

Indexed keywords

EPIDERMAL GROWTH FACTOR; GLYCOPROTEIN; MEMBRANE PROTEIN; MICROSOMAL AMINOPEPTIDASE; MONOSACCHARIDE; NOTCH RECEPTOR; SCA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DROSOPHILA; ENDOSOME; EYE DEVELOPMENT; GENE MUTATION; GENETIC ANALYSIS; MOSAICISM; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOSOMES; GLYCOPROTEINS; INSECT PROTEINS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MOSAICISM; PHENOTYPE; PHOTORECEPTORS, INVERTEBRATE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; WING;

ANIMALIA;

EID: 0038445524     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00495     Document Type: Article

References (57)

1. Artavanis-Tsakonas, S., Rand, M. D. and Lake, R. J. (1999). Notch signaling: cell fate control and signal integration in development. Science 284, 770-776.
2. Baker, N. E. (2000). Notch signalling in the nervous system. Pieces still missing from the puzzle. BioEssays 22, 264-273.
3. Baker, N. E. and Zitron, A. E. (1995). Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous. Mech. Dev. 49, 173-189.
4. Baker, N. E., Mlodzik, M. and Rubin, G. M. (1990). Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous. Science 250, 1370-1377.
5. Berdnik, D., Torok, T., Gonzalez-Gaitan, M. and Knoblich, J. A. (2002). The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev. Cell 3, 221-231.
6. Brand, M. and Campos-Ortega, J. A. (1990). Second site modifiers of the split mutation of Notch define genes involved in neurogenesis in Drosophila melanogaster. Roux's Arch. Dev. Biol. 198, 275-285.
7. Cho, K. O. and Choi, K. W. (1998). Fringe is essential for mirror symmetry and morphogenesis in the Drosophila eye. Nature 396, 272-276.
8. Chou, Y. H. and Chien, C. T. (2002). Scabrous controls ommatidial rotation in the Drosophila compound eye. Dev. Cell 3, 839-850.
9. Chung, H. M. and Struhl, G. (2001). Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila. Nat. Cell Biol. 3, 1129-1132.
10. Couso, J. P. and Martinez Arias, A. (1994). Notch is required for wingless signaling in the epidermis of Drosophila. Cell 79, 259-272.
11. de Celis, J. F., Barrio, R., del Arco, A. and Garcia-Bellido, A. (1993). Genetic and molecular characterization of a Notch mutation in its Delta- and Serrate-binding domain in Drosophila. Proc. Natl. Acad. Sci. USA 90, 4037-4041.
12. Doherty, D., Feger, G., Younger-Sheperd, S., Jan, L. Y. and Jan, Y. N. (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434.
13. Doherty, D., Jan, L. Y. and Jan, Y. N. (1997). The Drosophila neurogenic gene big brain, which encodes a membrane-associated protein, acts cell autonomously and can act synergistically with Notch and Delta. Development 124, 3881-3893.
14. Dominguez, M. and de Celis, J. F. (1998). A dorsal/ventral boundary established by Notch controls growth and polarity in the Drosophila eye. Nature 396, 276-278.
15. Ellis, M. C., Weber, U., Wiersdorff, V. and Mlodzik, M. (1994). Confrontation of scabrous expressing and non-expressing cells is essential for normal ommatidial spacing in the Drosophila eye. Development 120, 1959-1969.
16. Entchev, E. V., Schwabedissen, A. and Gonzalez-Gaitan, M. (2000). Gradient formation of the TGF-beta homolog Dpp. Cell 103, 981-991.
17. Fashena, S. J. and Zinn, K. (1997). Transmembrane glycoprotein Gp150 is a substrate for receptor tyrosine phosphatase Dptp10D in Drosophila cells. Mol. Cell. Biol. 17, 6859-6867.
18. Fehon, R. G., Kooh, P. J., Rebay, I., Regan, C. L., Xu, T., Muskavitch, M. A. and Artavanis-Tsakonas, S. (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous gene in Dropsophila. Cell 61, 657-669.
19. Fehon, R. G., Johansen, K., Rebay, I. and Artavanis-Tsakonas, S. (1991). Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: implications for Notch function. J. Cell Biol. 113, 657-669.
20. Fetchko, M., Huang, W., Li, Y. and Lai, Z. C. (2002). Drosophila Gp150 is required for early ommatidial development through modulation of Notch signaling. EMBO J. 21, 1074-1083.
21. Golic, K. G. (1991). Site-specific recombination between homologous chromosomes in Drosophila. Science 252, 958-961.
22. Hu, X., Lee, E.-C. and Baker, N. E. (1995). Molecular analysis of scabrous mutant alleles from Drosophila indicates a secreted protein with two functional domains. Genetics 141, 607-617.
23. Jacobsen, T. L., Brennan, K., Martinez-Arias, A. and Muskavitch, M. A. (1998). Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila. Development 125, 4531-4540.
24. Justice, N. J. and Jan, Y. N. (2002). Variations on the Notch pathway in neural development. Curr. Opin. Neurobiol. 12, 64-70.
25. Klein, T., Brennan, K. and Martinez-Arias, A. (1997). An intrinsic dominant negative activity of serrate that is regulated during wing development in Drosophila. Dev. Biol. 189, 123-134.
26. Komada, M., Masaki, R., Yamamoto, A. and Kitamura, N. (1997). Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J. Biol. Chem. 272, 20538-20544.
27. Lee, E. and Baker, N. E. (1996). GP300sca is not a high affinity ligand for Notch. Biochem. Biophys. Res. Commun. 225, 720-725.
28. Lee, E.-C., Hu, X., Yu, S. Y. and Baker, N. E. (1996). The scabrous gene encodes a secreted glycoprotein dimer and regulates proneural development in Drosophila eyes. Mol. Cell. Biol. 16, 1179-1188.
29. Lee, E.-C., Yu, S.-Y., Hu, X., Mlodzik, M. and Baker, N. E. (1998). Functional analysis of the Fibrinogen-related scabrous gene from Drosophila melanogaster identifies potential effector and stimulatory protein domains. Genetics 150, 663-673.
30. Lee, E.-C., Yu, S.-Y. and Baker, N. E. (2000). The SCABROUS protein can act as an extracellular antagonist of Notch signaling in the Drosophila wing. Curr. Biol. 10, 931-934.
31. Lee, T. and Luo, L. (1999). Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22, 451-461.
32. Li, Y. and Baker, N. E. (2001). Proneural enhancement by Notch overcomes Suppressor-of-Hairless repressor function in the developing Drosophila eye. Curr. Biol. 11, 330-338.
33. Li, Y., Lei, L., Irvine, K. D. and Baker, N. E. (2003). Notch activity in neural cells triggered by a mutation with altered glycosylation. Development 130, 2829-2840.
34. Lindsley, D. L. and Zimm, G. G. (1992). The Genome of Drosophila melanogaster. New York: Academic Press.
35. Lloyd, T. E., Atkinson, R., Wu, M. N., Zhou, Y., Penntta, G. and Bellen, H. J. (2002). HRS regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell 108, 261-269.
36. Lopez-Schier, H. and St Johnston, D. (2002). Drosophila Nicastrin is essential for the intramembranous cleavage of Notch. Dev. Cell 2, 79-89.
37. Micchelli, C. A., Rulifson, E. J. and Blair, S. S. (1997). The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. Development 124, 1485-1495.
38. Mlodzik, M., Baker, N. E. and Rubin, G. M. (1990). Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila. Genes Dev. 4, 1848-1861.
39. Mumm, J. S. and Kopan, R. (2000). Notch signaling: from the outside in. Dev. Biol. 228, 151-165.
40. Nolo, R., Abbot, L. A. and Bellen, H. J. (2000). Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila. Cell 102, 349-362.
41. Oda, H., Uemura, T., Harada, Y., Iwai, Y. and Takeichi, M. (1994). A Drosophila homolog of cadherin associated with Armadillo and essential for embryonic cell-cell adhesion. Dev. Biol. 165, 716-726.
42. Papayannopoulos, V., Tomlinson, A., Panin, V. M., Rauskolb, C. and Irvine, K. D. (1998). Dorsal-ventral signaling in the Drosophila eye. Science 281, 2031-2034.
43. Parks, A. L., Klueg, K. M., Stout, J. R. and Muskavitch, M. A. (2000). Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development 127, 1373-1385.
44. Powell, P. A., Wesley, C. S., Spencer, S. and Cagan, R. L. (2001). Scabrous complexes with Notch to mediate boundary formation. Nature 409, 626-630.
45. Rabinow, L. and Birchler, J. A. (1990). Interactions of vestigial and scabrous with the Notch locus of Drosophila melanogaster. Genetics 125, 41-50.
46. Rebay, I., Fleming, R. J., Fehon, R. G., Cherbas, L., Cherbas, P. and Artavanis-Tsakonas, S. (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67, 687-699.
47. Renaud, O. and Simpson, P. (2001). scabrous modifies epithelial cell adhesion and extends the range of lateral signalling during development of the spaced bristle pattern in Drosophila. Dev. Biol. 240, 361-376.
48. Rubin, G. M. and Spradling, A. C. (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.
49. Seugnet, L., Simpson, P. and Haenlin, P. (1997). Requirement for dynamin during Notch signaling in Drosophila neurogenesis. Dev. Biol. 192, 585-598.
50. Shaye, D. D. and Greenwald, I. (2002). Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans. Nature 420, 686-690.
51. Staehling-Hampton, K., Jackson, P. D., Clark, M. J., Brand, A. H. and Hoffmann, F. M. (1994). Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A. Cell Growth Diff. 5, 585-593.
52. Steller, H. and Pirrotta, V. (1986). P transposons controlled by the heat shock promoter. Mol. Cell. Biol. 6, 1640-1649.
53. Tian, S.-S. and Zinn, K. (1994). An adhesion molecule-like protein that interacts with and is a substrate for a Drosophila receptor-linked protein tyrosine phosphatase. J. Biol. Chem. 269, 28478-28486.
54. Tomlinson, A. and Ready, D. F. (1987). Cell fate in the Drosophila ommatidium. Dev. Biol. 123, 264-275.
55. Vincent, J., Girdham, C. and O'Farrell, P. (1994). A cell-autonomous, ubiquitous marker for the analysis of Drosophila genetic mosaics. Dev. Biol. 164, 328-331.
56. Weinmaster, G. (2000). Notch signaling: a real rip and more. Curr. Opin. Genet. Dev. 10, 363-369.
57. Xu, T. and Rubin, G. M. (1993). Analysis of genetic mosaics in the developing and adult Drosophila tissues. Development 117, 1223-1236.