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Volumn 125, Issue 28, 2003, Pages 8476-8485

Allosteric inhibition of protein-DNA complexes by polyamide-intercalator conjugates

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC INHIBITION;

EID: 0038375540     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja030125e     Document Type: Article
Times cited : (66)

References (60)
  • 5
    • 0035962636 scopus 로고    scopus 로고
    • (a) Pandolfi, P. P. Oncogene 2001, 20, 3116-3127.
    • (2001) Oncogene , vol.20 , pp. 3116-3127
    • Pandolfi, P.P.1
  • 48
    • 0038342916 scopus 로고    scopus 로고
    • note
    • All relaxation reactions were run at a sufficiently high (and constant) binding site-to-polyamide ratio to ensure that unwinding effects were only caused by sequence-specific interactions.
  • 49
    • 0038681490 scopus 로고    scopus 로고
    • note
    • The 60 amino acid sequence (222-281) of GCN4 contains the 'leucine zipper' dimerization domain and the 'basic region' responsible for DNA binding.
  • 50
    • 0038342914 scopus 로고    scopus 로고
    • note
    • The effects of polyamide-acridine conjugates binding only to the upstream site showed similar GCN4 inhibition values as ARE-41.
  • 54
    • 0022693818 scopus 로고
    • (a) Dervan, P. B. Science 1986, 232, 464-471.
    • (1986) Science , vol.232 , pp. 464-471
    • Dervan, P.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.