Cell cycle-dependent transduction of cell-permeant Cre recombinase proteins

Journal of Cellular Biochemistry

Volumn 89, Issue 4, 2003, Pages 674-687

  Jo, Daewoong ^a   Lin, Qing ^a   Nashabi, Abudi ^a   Mays, Deborah J ^a   Unutmaz, Derya ^a   Pietenpol, Jennifer A ^a   Ruley, H Earl ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MCN   (United States)

Author keywords

Cell cycle; Membrane transport; Protein transduction; Proteomics

Indexed keywords

CRE RECOMBINASE;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL MEMBRANE PERMEABILITY; CELL SIZE; CONTROLLED STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TRANSPORT; PROTEOMICS;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BLOTTING, SOUTHERN; CELL CYCLE; CELL MEMBRANE PERMEABILITY; CELL SIZE; CELLS, CULTURED; DNA, BACTERIAL; ESCHERICHIA COLI; FLOW CYTOMETRY; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; INTEGRASES; LUMINESCENT PROTEINS; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC; SIGNAL TRANSDUCTION; VIRAL PROTEINS;

EID: 0038311722     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10542     Document Type: Article

References (50)

1. Berlin RD, Oliver JM, Walter RJ. 1978. Surface functions during mitosis I: Phagocytosis, pinocytosis, and mobility of surface-bound Con A. Cell 15:327-341.
2. Cunningham CC, Vegners R, Bucki R, Funaki M, Korde N, Hartwig JH, Stossel TP, Janmey PA. 2001. Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly. J Biol Chem 30:30.
3. Datta K, Sundberg C, Karumanchi SA, Mukhopadhyay D. 2001. The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion. Cancer Res 61:1768-1775.
4. de Laat SW, van der Saag PT, Shinitzky M. 1977. Microviscosity modulation during the cell cycle of neuroblastoma cells. Proc Natl Acad Sci USA 74:4458-4461.
5. de Laat SW, van der Saag PT, Elson EL, Schlessinger J. 1980. Lateral diffusion of membrane lipids and proteins during the cell cycle of neuroblastoma cells. Proc Natl Acad Sci USA 77:1526-1528.
6. Derossi D, Joliot AH, Chassaing G, Prochiantz A. 1994. The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem 269: 10444-10450.
7. Derossi D, Williams EJ, Green PJ, Dunican DJ, Doherty P. 1998. Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide. Biochem Biophys Res Commun 251:148-152.
8. Dunican DJ, Doherty P. 2001. Designing cell-permeant phosphopeptides to modulate intracellular signaling pathways. Biopolymers 60:45-60.
9. Elliott G, O'Hare P. 1997. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 88:223-233.
10. Ezhevsky SA, Nagahara H, Vocero-Akbani AM, Gius DR, Wei MC, Dowdy SF. 1997. Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb. Proc Natl Acad Sci USA 94:10699-10704.
11. Ezhevsky SA, Ho A, Becker-Hapak M, Davis PK, Dowdy SF. 2001. Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo. Mol Cell Biol 21:4773-4784.
12. Fujihara SM, Cleaveland JS, Grosmaire LS, Berry KK, Kennedy KA, Blake JJ, Loy J, Rankin BM, Ledbetter JA, Nadler SG. 2000. A D-amino acid peptide inhibitor of NF-kappa B nuclear localization is efficacious in models of inflammatory disease. J Immunol 165:1004-1012.
13. Gius DR, Ezhevsky SA, Becker-Hapak M, Nagahara H, Wei MC, Dowdy SF. 1999. Transduced p16INK4a peptides inhibit hypophosphorylation of the retinoblastoma protein and cell cycle progression prior to activation of Cdk2 complexes in late G1. Cancer Res 59:2577-2580.
14. Grdina DJ, Meistrich ML, Meyn RE, Johnson TS, White A. 1986. Cell synchrony techniques: A comparison of methods. In: Gray JW, Darzynkiewicz Z, editors. Techniques in cell cycle analysis. Clifton, NJ: Humana Press. pp 367-402.
15. Hall H, Williams EJ, Moore SE, Walsh FS, Prochiantz A, Doherty P. 1996. Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide. Curr Biol 6:580-587.
16. Hall DJ, Cui J, Bates ME, Stout BA, Koenderman L, Coffer PJ, Bertics PJ. 2001. Transduction of a dominant-negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability. Blood 98:2014-2021.
17. Hawiger J. 1999. Noninvasive intracellular delivery of functional peptides and proteins. Curr Opin Chem Biol 3:89-94.
18. Huang S. 2000. The practical problems of post-genomic biology. Nat Biotechnol 18:471-472.
19. Illinger D, Italiano L, Beck JP, Waltzinger C, Kuhry JG. 1993. Comparative evolution of endocytosis levels and of the cell surface area during the L929 cell cycle: A fluorescence study with TMA-DPH. Biol Cell 79:265-268.
20. Incardona JP, Eaton S. 2000. Cholesterol in signal transduction. Curr Opin Cell Biol 12:193-203.
21. Jo D, Nashabi A, Doxsee C, Lin Q, Unutmaz D, Chen J, Ruley HE. 2001. Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nat Biotechnol 19:929-933.
22. Joshi SK, Hashimoto K, Koni PA. 2002. Induced DNA recombination by Cre recombinase protein transduction. Genesis 33:48-54.
23. Knutton S, Sumner MC, Pasternak CA. 1975. Role of microvilli in surface changes of synchronized P815Y mastocytoma cells. J Cell Biol 66:568-576.
24. Lai CS, Hopwood LE, Swartz HM. 1980. Electron spin resonance studies of changes in membrane fluidity of Chinese hamster ovary cells during the cell cycle. Biochim Biophys Acta 602:117-126.
25. Lin YZ, Yao SY, Veach RA, Torgerson TR, Hawiger J. 1995. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J Biol Chem 270:14255-14258.
26. Liu KY, Timmons S, Lin YZ, Hawiger J. 1996. Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs. Proc Natl Acad Sci USA 93:11819-11824.
27. Lundberg M, Johansson M. 2001. Is VP22 nuclear homing an artifact? Nat Biotechnol 19:713.
28. Mann DA, Frankel AD. 1991. Endocytosis and targeting of exogenous HIV-1 Tat protein. EMBO J 10:1733-1739.
29. May MJ, D'Acquisto F, Madge LA, Glockner J, Pober JS, Ghosh S. 2000. Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 289:1550-1554.
30. Morris MC, Vidal P, Chaloin L, Heitz F, Divita G. 1997. A new peptide vector for efficient delivery of oligonucleotides into mammalian cells. Nucleic Acids Res 25:2730-2736.
31. Morris MC, Depollier J, Mery J, Heitz F, Divita G. 2001. A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat Biotechnol 19:1173-1176.
32. Oliver JM, Seagrave JC, Pfeiffer JR, Feibig ML, Deanin GG. 1985. Surface functions during mitosis in rat basophilic leukemia cells. J Cell Biol 101:2156-2166.
33. Pan DA, Sullivan-Tailyour G, Hulbert AJ. 1990. Membrane fatty acid changes during the cell cycle of CV-1 cells. Exp Cell Res 191:141-143.
34. Peitz M, Pfannkuche K, Rajewsky K, Edenhofer F. 2002. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes. Proc Natl Acad Sci USA 99:4489-4494.
35. Pellegrin P, Fernandez A, Lamb NJ, Bennes R. 2002. Macromolecular uptake is a spontaneous event during mitosis in cultured fibroblasts: Implications for vector-dependent plasmid transfection. Mol Biol Cell 13:570-578.
36. Phelan A, Elliott G, O'Hare P. 1998. Intercellular delivery of functional p53 by the herpesvirus protein VP22. Nat Biotechnol 16:440-443.
37. Rojas M, Yao S, Lin YZ. 1996. Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor. J Biol Chem 271:27456-27461.
38. Schlegel A, Pestell RG, Lisanti MP. 2000. Caveolins in cholesterol trafficking and signal transduction: Implications for human disease. Front Biosci 5:D929-D937.
39. Schwarze SR, Dowdy SF. 2000. In vivo protein transduction: Intracellular delivery of biologically active proteins, compounds, and DNA. Trends Pharmacol Sci 21:45-48.
40. Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. 1999. In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 285:1569-1572.
41. Torgerson TR, Colosia AD, Donahue JP, Lin YZ, Hawiger J. 1998. Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50. J Immunol 161:6084-6092.
42. Vastrik I, Eickholt BJ, Walsh FS, Ridley A, Doherty P. 1999. Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32. Curr Biol 9:991-998.
43. Vocero-Akbani AM, Heyden NV, Lissy NA, Ratner L, Dowdy SF. 1999. Killing HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein. Nat Med 5:29-33.
44. Will E, Klump H, Heffner N, Schwieger M, Schiedlmeier B, Ostertag W, Baum C, Stocking C. 2002. Unmodified Cre recombinase crosses the membrane. Nucleic Acids Res 30:e59.
45. Williams EJ, Dunican DJ, Green PJ, Howell FV, Derossi D, Walsh FS, Doherty P. 1997. Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide. J Biol Chem 272:22349-22354.
46. Wu W, Lee WL, Wu YY, Chen D, Liu TJ, Jang A, Sharma PM, Wang PH. 2000. Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells. J Biol Chem 275:40113-40119.
47. Yan Liu X, Robinson D, Veach RA, Liu D, Timmons S, Collins RD, Hawiger J. 2000. Peptide-directed suppression of a pro-inflammatory cytokine response. J Biol Chem 275:16774-16778.
48. Yao BB, Niu P, Surowy CS, Faltynek CR. 1999. Direct interaction of STAT4 with the IL-12 receptor. Arch Biochem Biophys 368:147-155.
49. Yigzaw Y, Cartin L, Pierre S, Scholich K, Patel TB. 2001. The C terminus of sprouty is important for modulation of cellular migration and proliferation. J Biol Chem 276: 22742-22747.
50. Zezula J, Casaccia-Bonnefil P, Ezhevsky SA, Osterhout DJ, Levine JM, Dowdy SF, Chao MV, Koff A. 2001. p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal. EMBO Rep 2: 27-34.