Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide

Current Biology

Volumn 6, Issue 5, 1996, Pages 580-587

  Hall, Heike ^a   Williams, Emma J ^a,c   Moore, Stephen E ^a   Walsh, Frank S ^a   Prochiantz, Alain ^b   Doherty, Patrick ^a  

^a GUY S HOSPITAL   (United Kingdom)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

VISCUM ALBUM;

FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; ISOENZYME; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOPEPTIDE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; DRUG ANTAGONISM; HYDROLYSIS; METABOLISM; MOLECULAR GENETICS; NEURITE; RAT;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; FIBROBLAST GROWTH FACTOR 2; HYDROLYSIS; ISOENZYMES; MOLECULAR SEQUENCE DATA; NEURITES; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOPEPTIDES; RATS; RECEPTORS, FIBROBLAST GROWTH FACTOR;

EID: 0030133937     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00544-4     Document Type: Article

References (34)

1. Schlessinger J: SH2/SH3 signalling proteins. Curr Opin Gen Dev 1994, 4:25-30.
2. Margolis B, Rhee SG, Felder S, Mervic M, Lyall R, Levitzki A, et al.: EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signalling. Cell 1989, 57:1101-1107.
3. Meisenhelder J, Suh PG, Rhee SG, Hunter T: Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein tyrosine kinases in vivo and in vitro. Cell 1989, 57:1109-1122.
4. Wahl MI, Nishibe S, Suh PG , Rhee SG, Carpenter G: Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalisation and extracellular calcium. Proc Nat Acad Sci USA 1989, 86:1568-72.
5. Burgess WH, Dionne CA, Kaplow J, Mudd R, Friesel R, Zilberstein A, et al.: Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Mol Cell Biol 1990, 10:4770-4777.
6. Middlemas DS, Meisenhelder J, Hunter T: Identification of TrkB autophosphorylation sites and evidence that phospholipase C-gamma 1 is a substrate of the TrkB receptor. J Biol Chem 1994, 269:5458-5466.
7. Mohammadi M, Honegger AM, Rotin D, Fischer R, Bellot F, Li W, et al.: A tyrosine phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1. Mol Cell Biol 1991, 11:5068-5078.
8. Mohammadi M, Dionne C A, Li W, Li N, Spivak T, Honegger AM, et al.: Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature 1992, 358:681-684.
9. 2+ flux but not mitogenesis. Nature 1992, 358:678-681.
10. Felder S, Zhou M, Hu P, Urena J, Ullrich A, Chaudhuri M et al.: SH2 domains exhibit high-affinity binding to tyrosine phosphorylated peptides yet also exhibit rapid dissociation and exchange. Mol Cell Biol 1993, 13:1449-1455.
11. Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG et al.: SH2 domains recognize specific phosphopeptide sequences. Cell 1993, 72:767-778.
12. McNamara DJ, Dobrusin, EM, Zhu G, Decker SJ, Saltiel A: Inhibition of binding of phospholipase C gamma 1 SH2 domains to phosphorylated epidermal growth factor receptor by phosphorylated peptides. Int J Pept Protein Res 1994, 43:240-248.
13. Pascal SM, Singer AU, Gish G, Yamazaki T, Shoelson SE, Pawson T, et al.: Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell 1994, 77:461-472.
14. Eriksson A, Nanberg E, Ronnstrand L, Engstrom U, Hellman U, Rupp E, et al.: Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet derived growth factor receptors. J Biol Chem 1995, 270:7773-7781.
15. Derossi D, Joliot A H, Chassaing G, Prochiantz A: The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem 1994, 269:10444-10450.
16. Theodore L, Derossi D, Chassaing G, Llirbat B, Miroslav K, Pascale J, et al.: Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse. J Neurosci 1995, 15:7158-7167.
17. Cole SR, Ashman LK, Ey PL: Biotinylation: an alternative to radioiodination for the identification of cell surface antigens in immunoprecipitates. Mol Immunol 1987, 24:699-705.
18. Claesson-Welsh L: Signal transduction by the PDGF receptors. Prog Growth Factor Res 1994, 5:37-54.
19. Guiton M, Gunn-Moore FJ, Glass DJ, Geis DR, Yancopoulos GD, Tavare JM: Naturally occurring tyrosine kinase inserts block high affinity binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3 signalling. J Biol Chem 1995, 270:20384-20390.
20. Lamballe F, Tapley P, Barbacid M: TrkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities. EMBO J 1993, 12:3083-3094.
21. Obermeier A, Halfter H, Wiesmuller KH, Jung G, Schlessinger J, Ullrich A: Tyrosine 785 is a major determinant of Trk-substrate interaction. EMBO J 1993, 12:933-941.
22. Schor KJ: Role of prostaglandins in the cardiovascular effects of bradykinin and angiotensin-converting enzyme inhibitors. J Cardiovasc Pharmacol 1992, 20:568-73.
23. Williams EJ, Furness J, Walsh FS, Doherty P: Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF. Development 1994, 120:1685-1693.
24. Williams EJ, Mittal, B, Walsh FS, Doherty P: FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules. J Cell Sci 1995, 108:3523-3530.
25. Kemp B: Pseudosubstrate-based peptide inhibitors. Methods Enzymol 1991, 201:287-304.
26. Allinquant B, Hantraye P, Mailleux P, Moya K, Bouillot C, Prochiantz A: Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro. J Cell Biol 1995, 128:919-927.
27. Godpodarowicz D: Fibroblast growth factor and its involvement in developmental processes. Curr Topics Dev Biol 1990, 24: 57-93.
28. Hatten ME, Lynch M, Rydel RE, Sanchez J, Joseph-Silverstein J, Moscatelli D, Rifkin DB: In vitro neurite extension by granule neurons is dependent upon astroglial-derived fibroblast growth factor. Dev Biol 1988, 125:280-289.
29. Morrison RS, Sharma A, de Vellis J, Bradshaw RA: Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture. Proc Natl Acad Sci USA 1986, 83:7537-7541.
30. Anderson DJ: Molecular control of cell fate in the neural crest: the sympathodrenal lineage. Annu Rev Neurosci 1993, 16:129-58.
31. Spivak-Krozman T, Mohammadi M, Hu P, Jaye M, Schlessinger J, Lax I: Point mutation in the fibroblast growth factor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells. J Biol Chem 1994, 269:14419-14423.
32. Togari A, Dickens G, Kuzuya H, Guroff G: The effect of fibroblast growth factor on PC12 cells. J Neurosci 1985, 5:307-316.
33. Schnitzer J, Schachner M: Characterization of isolated mouse cerebellar cell populations in vivo. J Neuroimmunol 1981, 1:457-470.
34. Taylor CW, Blakeley DM, Corps AN, Berridge MJ, Brown KD: Effects of pertussis toxin on growth factor-stimulated inositol phosphate formation and DNA synthesis in Swiss 3T3 cells. Biochem J 1988, 249:917-920.