Thieno[3,2-b]- and thieno[2,3-b]pyrrole bioisosteric analogues of the hallucinogen and serotonin agonist N,N-dimethyltryptamine

Journal of Medicinal Chemistry

Volumn 42, Issue 6, 1999, Pages 1106-1111

  Blair, Joseph B ^a   Marona Lewicka, Danuta ^a   Kanthasamy, Arthi ^a   Lucaites, Virginia L ^b   Nelson, David L ^b   Nichols, David E ^a  

^a PURDUE UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 (N,N DIMETHYLAMINO)ETHYL] 6H THIENO[2,3 B]PYRROLE; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6 [2 (N,N DIMETHYLAMINO)ETHYL] 4H THIENO[3,2 B]PYRROLE; 6 ACETYL 4 (DI N PROPYLAMINO) 1,3,4,5 TETRAHYDROBENZ[C,D]INDOLE; LY 293284; LYSERGIDE; N,N DIMETHYLTRYPTAMINE; PSYCHEDELIC AGENT; SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN AGONIST; THIENO[2,3 B]PYRROLE DERIVATIVE; THIENO[3,2 B]PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DISCRIMINATION; DRUG SYNTHESIS; FIBROBLAST; HAMSTER; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; SALIVATION; SEROTONIN SYNDROME;

AMPHETAMINES; ANIMALS; CELL LINE; CLONING, MOLECULAR; CRICETINAE; DISCRIMINATION LEARNING; HALLUCINOGENS; HUMANS; LYSERGIC ACID DIETHYLAMIDE; MALE; N,N-DIMETHYLTRYPTAMINE; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2B; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; THIOPHENES; TRYPTAMINES;

EID: 0033602547     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980692q     Document Type: Article

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