Development of a liquid culture system for megakaryocyte terminal differentiation: Fibrinogen promotes megakaryocytopoiesis but not thrombopoiesis

British Journal of Haematology

Volumn 121, Issue 2, 2003, Pages 315-323

  Sato, Takahiro ^a,b   Ono, Minoru ^b   Fujita, Hiroshi ^c   Tanaka, Nobuhito ^a   Tomiyama, Junji ^c   Sakamoto, Yujiro ^a   Takano, Yoshiro ^a   Murota, Sei Itsu ^a   Morita, Ikuo ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Radio Research Lab   (Japan)

^c TOKYO METROPOLITAN BOKUTOH HOSPITAL   (Japan)

Author keywords

Hematopoietic stem cells; Human; Megakaryocytes; Thrombopoiesis; Transcription factors

Indexed keywords

CD34 ANTIGEN; FIBRINOGEN RECEPTOR; GLYCOPROTEIN IIB; PROPIDIUM IODIDE; THROMBOXANE SYNTHASE; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR NF E2;

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL SELECTION; CONTROLLED STUDY; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LIQUID CULTURE; MEGAKARYOPOIESIS; NEWBORN; NORMAL HUMAN; PRIORITY JOURNAL; STEM CELL; THROMBOCYTOPOIESIS; TRANSMISSION ELECTRON MICROSCOPY; UMBILICAL CORD BLOOD;

ANTIGENS, CD34; BIOLOGICAL MARKERS; BLOOD PLATELETS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; CULTURE MEDIA; FIBRINOGEN; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; HUMANS; MEGAKARYOCYTES; MICROSCOPY, ELECTRON; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET MEMBRANE GLYCOPROTEIN IIB; STEM CELL FACTOR; THROMBOPOIETIN;

EID: 0038217075     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04266.x     Document Type: Article

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