Isolation and characterization of Bud6p, an actin interacting protein, from Yarrowia lipolytica

Journal of Microbiology

Volumn 41, Issue 2, 2003, Pages 121-128

  Song, Yunkyoung ^a   Cheon, Seon Ah ^a   Lee, So Yeon ^a   Hwang, Ji Sook ^a   Kim, Jeong Yoon ^a  

^a Chungnam National University   (South Korea)

Author keywords

BUD6; Cell polarity; Hyphae; Yarrowia lipolytica; Yeast

Indexed keywords

ACTIN; AMINO ACID; FUNGAL PROTEIN; N ACETYLGLUCOSAMINE; PROTEIN BUD6P; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; ARTICLE; CELL POLARITY; CONTROLLED STUDY; DIPLOIDY; FUNGAL GENE; FUNGAL MORPHOLOGY; FUNGAL STRAIN; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS MUTANT; GENE DISRUPTION; GENE ISOLATION; GENE SWITCHING; HAPLOIDY; MORPHOGENESIS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY; SERUM; SPECIES COMPARISON; WILD TYPE; YARROWIA LIPOLYTICA; YEAST;

FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE; YARROWIA LIPOLYTICA;

EID: 0038119299     PISSN: 12258873     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Amberg, D.C., J.E. Zahner, J.W. Mulholland, J.R. Pringle, and D. Botstein. 1997. Aip3p/Bud6p, a yeast actin-interacting protein that is involved in morphogenesis and the selection of bipolar budding sites. Mol. Biol. Cell 8, 729-753.
2. Barth, G. and C. Gaillardin. 1996. Yarrowia lipolytica, p. 313-388. In K. Wolf (ed.), Nonconventional yeasts in biotechnology. Springer-Verlag, Berlin Heidelberg.
3. Bensen, E.S., S.G. Filler, and J. Berman. 2002. A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans. Eukaryot. Cell 1, 787-798.
4. Brown, A.J. and N.A. Gow. 1999. Regulatory networks controlling Candida albicans morphogenesis. Trends Microbiol. 7, 333-338.
5. Calderone, R.A. and W.A. Fonzi. 2001. Virulence factors of Candida albicans. Trends Microbiol. 9, 327-335.
6. Calera, J.A. and R. Calderone. 1999. Histidine kinase, two-component signal transduction proteins of Candida albicans and the pathogenesis of candidosis. Mycoses 42 Suppl 2, 49-53.
7. Calera, J.A., X.J. Zhao, and R. Calderone. 2000. Defective hyphal development and avirulence caused by a deletion of the SSK1 response regulator gene in Candida albicans. Infect. Immun. 68, 518-525.
8. Evangelista, M., K. Blundell, M.S. Longtine, C.J. Chow, N. Adames, J.R. Pringle, M. Peter, and C. Boone. 1997. Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 276, 118-122.
9. Freedman, T., A. Porter, and B. Haarer. 2000. Mutational and hyper-expression-induced disruption of bipolar budding in yeast. Microbiology 146 (Pt 11), 2833-2843.
10. Gancedo, J.M. 2001. Control of pseudohyphae formation in Saccharomyces cerevisiae. FEMS Microbiol. Rev. 25, 107-123.
11. Gimeno, C.J. and G.R. Fink. 1994. Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development. Mol. Cell. Biol. 14, 2100-2112.
12. Glynn, J.M., R.J. Lustig, A. Berlin, and F. Chang. 2001. Role of bud6p and tea1p in the interaction between actin and microtubules for the establishment of cell polarity in fission yeast. Curr. Biol. 11, 836-845.
13. Gow, N.A. 1997. Germ tube growth of Candida albicans. Curr. Top. Med. Mycol. 8, 43-55.
14. Herrero, A.B., M.C. Lopez, L.F. Lago, and A. Dominguez. 1999. Candida albicans and Yarrowia lipolytica as alternative models for analysing budding patterns and germ tube formation in dimorphic fungi. Microbiology 145 (Pt 10), 2727-2737.
15. Ho, J. and A. Bretscher. 2001. Ras regulates the polarity of the yeast actin cytoskeleton through the stress response pathway. Mol. Biol. Cell 12, 1541-1555.
16. Hurtado, C.A., J.M. Beckerich, C. Gaillardin, and R.A. Rachubinski. 2000. A rac homolog is required for induction of hyphal growth in the dimorphic yeast Yarrowia lipolytica. J. Bacteriol. 182, 2376-2386.
17. Hurtado, C.A. and R.A. Rachubinski. 2002. Isolation and characterization of YlBEM1, a gene required for cell polarization and differentiation in the dimorphic yeast Yarrowia lipolytica. Eukaryot. Cell 1, 526-537.
18. Jaquenoud, M. and M. Peter. 2000. Gic2p may link activated Cdc42p to components involved in actin polarization, including Bni1p and Bud6p (Aip3p). Mol. Cell. Biol. 20, 6244-6258.
19. Jin, H. and D.C. Amberg. 2001. Fission yeast Aip3p (spAip3p) is required for an alternative actin-directed polarity program. Mol. Biol. Cell 12, 1275-1291.
20. Kadosh, D. and A.D. Johnson. 2001. Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans. Mol. Cell. Biol. 21, 2496-2505.
21. Kim, J., S.A. Cheon, S. Park, Y. Song, and J.-Y. Kim. 2000. Serum-induced hypha formation in the dimorphic yeast Yarrowia lipolytica. FEMS Microbiol. Lett. 190, 9-12.
22. Kim, J., S.A. Cheon, Y. Song, and J.-Y. Kim. 2002. Cloning and characterization of the multiprotein bridging factor 1 (YlMBF1) gene from the dimorphic yeast Yarrowia lipolytica. J. Microbiol. 40, 173-177.
23. Leberer, E., K. Ziegelbauer, A. Schmidt, D. Harcus, D. Dignard, J. Ash, L. Johnson and D.Y. Thomas. 1997. Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p. Curr. Biol. 7, 539-546.
24. Liu, H. 2001. Transcriptional control of dimorphism in Candida albicans. Curr. Opin. Microbiol. 4, 728-735.
25. Lo, H.J., J.R. Kohler, B. DiDomenico, D. Loebenberg, A. Cacciapuoti, and G.R. Fink. 1997. Nonfilamentous C. albicans mutants are avirulent. Cell 90, 939-949.
26. Magee, B.B. and P.T. Magee. 2000. Induction of mating in Candida albicans by construction of MTLa and MTLalpha strains. Science 289, 310-313.
27. McNemar, M.D. and W.A. Fonzi. 2002. Conserved serine/threonine kinase encoded by CBK1 regulates expression of several hypha-associated transcripts and genes encoding cell wall pro teins in Candida albicans. J. Bacteriol. 184, 2058-2061.
28. Michel, S., S. Ushinsky, B. Klebl, E. Leberer, D. Thomas, M. Whiteway, and J. Morschhauser. 2002. Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes. Mol. Microbiol. 46, 269-280.
29. Nakayama, H., T. Mio, S. Nagahashi, M. Kokado, M. Arisawa, and Y. Aoki. 2000. Tetracycline-regulatable system to tightly control gene expression in the pathogenic fungus Candida albicans. Infect. Immun. 68, 6712-6719.
30. Navarro-Garcia, F., M. Sanchez, C. Nombela, and J. Pla. 2001. Virulence genes in the pathogenic yeast Candida albicans. FEMS Microbiol. Rev. 25, 245-268.
31. Oberholzer, U., A. Marcil, E. Leberer, D.Y. Thomas, and M. Whiteway. 2002. Myosin I is required for hypha formation in Candida albicans. Eukaryot. Cell 1, 213-228.
32. Richard, M., R.R. Quijano, S. Bezzate, F. Bordon-Pallier, and C. Gaillardin. 2001. Tagging morphogenetic genes by insertional mutagenesis in the yeast Yarrowia lipolytica. J. Bacteriol. 183, 3098-3107.
33. Sambrook, J. and D.W. Russell. 2001. Molecular Cloning: A Laboratory Manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
34. Schweizer, A., S. Rupp, B.N. Taylor, M. Rollinghoff, and K. Schroppel. 2000. The TEA/ATTS transcription factor CaTec1p regulates hyphal development and virulence in Candida albicans. Mol. Microbiol. 38, 435-445.
35. Segal, M., K. Bloom, and S.I. Reed. 2002. Kar9p-independent microtubule capture at Bud6p cortical sites primes spindle polarity before bud emergence in Saccharomyces cerevisiae. Mol. Biol. Cell. 13, 4141-4155.
36. Sheu, Y.J., B. Santos, N. Fortin, C. Costigan, and M. Snyder. 1998. Spa2p interacts with cell polarity proteins and signaling components involved in yeast cell morphogenesis. Mol. Cell. Biol. 18, 4053-4069.
37. Stoldt, V.R., A. Sonneborn, C.E. Leuker, and J.F. Ernst. 1997. Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J. 16, 1982-1991.
38. Sudbery, P.E. 2001. The germ tubes of Candida albicans hyphae and pseudohyphae show different patterns of septin ring localization. Mol. Microbiol. 41, 19-31.
39. Thompson, J.D., D.G. Higgins, and T.J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4680.
40. Torres-Guzman, J.C. and A. Dominguez. 1997. HOY1, a homeo gene required for hyphal formation in Yarrowia lipolytica. Mol. Cell. Biol. 17, 6283-6293.