A novel specific bioassay for the determination of glucocorticoid bioavailability in human serum

Clinical Endocrinology

Volumn 59, Issue 1, 2003, Pages 49-55

  Vermeer, H ^a   Hendriks Stegeman, B I ^a   Van Den Brink, C E ^b   Van Der Saag, P T ^b   Van Der Burg, B ^b   Van Buul Offers, S C ^a   Jansen, M ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b BIODETECTION SYSTEMS B V   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; DEXAMETHASONE; ESTRADIOL; FLUTICASONE PROPIONATE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; LIGAND; LUCIFERASE; PROGESTERONE; STEROID HORMONE; TESTOSTERONE;

ARTICLE; BIOASSAY; BLOOD ANALYSIS; CIRCADIAN RHYTHM; CONTROLLED STUDY; CROSS REACTION; DNA RESPONSIVE ELEMENT; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFECT; DRUG HALF LIFE; DRUG POTENCY; EMBRYO; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INHALER; KIDNEY CELL; NORMAL HUMAN; PLASMID; PRIORITY JOURNAL;

ADMINISTRATION, INHALATION; ANDROSTADIENES; BIOLOGICAL ASSAY; BIOLOGICAL AVAILABILITY; BUDESONIDE; CELL LINE; DEXAMETHASONE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; LUCIFERASES; RECEPTORS, GLUCOCORTICOID; SENSITIVITY AND SPECIFICITY; TRANSFECTION;

EID: 0038095673     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2003.01793.x     Document Type: Article

References (37)

1. Andrews, R.C. & Walker, B.R. (1999) Glucocorticoids and insulin resistance: old hormones, new targets. Clinical Science, 96, 513-523.
2. Boot, A.M., De Jongste, J.C., Verberne, A.A., Pols, H.A. & De Muinck Keizer-Schrama, S. (1997) Bone mineral density and bone metabolism of prepubertal children with asthma after long-term treatment with inhaled corticosteroids. Pediatric Pulmonology., 24, 379-384.
3. Bronnegard, M. (1996) Steroid receptor number. Individual variation and downregulation by treatment. American Journal of Respiratory and Critical Care Medicine, 154, S28-S32.
4. Cassidy, F., Ritchie, J.C., Verghese, K. & Carroll, B.J. (2000) Dexamethasone metabolism in dexamethasone suppression test suppressors and nonsuppressors. Biological Psychiatry, 47, 677-680.
5. Crim, C., Pierre, L.N. & Daley-Yates, P.T. (2001) A review of the pharmacology and pharmacokinetics of inhaled fluticasone propionate and mometasone furoate. Clinical Therapy, 23, 1339-1354.
6. Dean, M., Stock, B., Patterson, R.J. & Levy, G. (1980) Serum protein binding of drugs during and after pregnancy in humans. Clinical Pharmacology and Therapeutics, 28, 253-261.
7. Delhaas, T., Jansen, M., Sinnema, G., De Schryver, J.E.A.R. & De Meer, K. (1998) Steroid-resistant inflammatory bowel disease: a patient with non-compliance in the hospital. European Journal of Pediatrics, 157, 443.
8. Dempsey, O.J., Coutie, W.J.R., Wilson, A.M., Williams, P. & Lipworth, B.J. (1999) Evaluation of the buccal component of systemic absorption with inhaled fluticasone propionate. Thorax, 54, 614-617.
9. Derendorf, H. (1997) Pharmacokinetic and pharmacodynamic properties of inhaled corticosteroids in relation to efficacy and safety. Respiriratory Medicine, 91 (Suppl. A), 22-28.
10. Duclos, M., Gatta, B., Corcuff, J.B., Rashedi, M., Pehourcq, F. & Roger, P. (2001) Fat distribution in obese women is associated with subtle alterations of the hypothalamic-pituitary-adrenal axis activity and sensitivity to glucocorticoids. Clinical Endocrinology, 55, 719-721.
11. Fowler, S.J., Orr, L.C., Wilson, A.M., Sims, E.J. & Lipworth, B.J. (2001) Dose-response for adrenal suppression with hydrofluoroalkane formulations of fluticasone propionate and beclomethasone dipropionate. British Journal of Clinical Pharmacology, 52, 93-95.
12. Grebe, S.K., Feek, C.M., Durham, J.A., Kljakovic, M. & Cooke, R.R. (1997) Inhaled beclomethasone dipropionate suppresses the hypothalamo-pituitary-adrenal axis in a dose-dependent manner. Clinical Endocrinology, 47, 297-304.
13. Hearing, S.D., Norman, M., Smyth, C., Foy, C. & Dayan, C.M. (1999) Wide variation in lymphocyte steroid sensitivity among healthy human volunteers. Journal of Clinical Endocrinology and Metabolism, 84, 4149-4154.
14. Holsboer, F. (2000) The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology, 23, 477-501.
15. Holsboer, F., Wiedemann, K., Gerken, A. & Boll, E. (1986) The plasma dexamethasone variable in depression: test-retest studies and early biophase kinetics. Psychiatry Research, 17, 97-103.
16. Huizenga, N.A., Koper, J.W., De Lange, P., Pols, H.A., Stolk, R.P., Burger, H., Grobbee, D.E., Brinkmann, A.O., De Jong, F.H. & Lamberts, S.W.J. (1998) A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo. Journal of Clinical Endocrinology and Metabolism, 83, 144-151.
17. Huizenga, N.A., De Lange, P., Koper, J.W., De Herder, W.W., Abstract, R., Kasteren, J.H.L.M.V., De Jong, F.H. & Lamberts, S.W.J. (2000) Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene. Journal of Clinical Endocrinology and Metabolism, 85, 2076-2081.
18. Johnson, M. (1996) Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids. Jounal of Allergy and Clinical Immunology, 97, 169-176.
19. Kannisto, S., Korppi, M., Remes, K. & Voutilainen, R. (2000) Adrenal suppression, evaluated by a low-dose adrenocorticotropin test, and growth in asthmatic children treated with inhaled steroids. Journal of Clinical Endocrinology and Metabolism, 85, 652-657.
20. Karlsson, R., Kallio, J., Irjala, K., Ekblad, S., Toppari, J. & Kero, P. (2000) Adrenocorticotropin and corticotropin-releasing hormone tests in pre-term infants. Journal of Clinical Endocrinology and Metabolism, 85, 4592-4595.
21. Kelly, H.W. (1999) Comparative potency and clinical efficiacy of inhaled corticosteroids. Respiratory Care Clinics of North America, 5, 537-553.
22. Kino, T. & Chrousos, G.P. (2001) Glucocorticoid and mineralocorticoid resistance/hypersensitivity syndromes. Journal of Endocrinology, 169, 437-445.
23. Lamberts, S.W., Huizenga, N.A., De Lange, P., De Jong, F.H. & Koper, J.W. (1996) Clinical aspects of glucocorticoid sensitivity. Steroids, 61, 157-160.
24. Legler, J., Van den Brink, C.E., Brouwer, A., Murk, A.J., Van der Saag, P.T., Vethaak, A.D. & Van der Burg, B. (1999) Development of a stably transfected estrogen-receptor mediated luciferase reporter gene assay in the human T47D breast cancer cell line. Toxicological Sciences, 48, 55-66.
25. Mayenknecht, J., Diederich, S., Bähr, V., Plöckinger, U., & Oelker, W. (1998) Comparison of low and high dose corticotropin stimulation tests in patients with pituitary disease. Journal of Clinical Endocrinology and Metabolism, 83, 1558-1562.
26. McKenna, N.J., Lanz, R.B. & O'Malley, B.W. (1999) Nuclear Receptor Coregulators: Cellular and Molecular Biology. Endocrine Reviews, 20, 321-344.
27. Nye, E.J., Grice, J.E., Hockings, G.I., Strakosch, C.R., Crosbie, G.V., Walters, M.M. & Jackson, R.V. (1999) Comparison of adrenocorticotropin (ACTH) stimulation tests and insulin hypoglycemia in normal humans: Dose, standard high-dose, and 8-hour ACTH-(1-24) infusion tests. Journal of Clinical Endocrinology and Metabolism, 84, 3648-3655.
28. O'Sullivan, B.T., Cutler, D.J., Hunt, G.E., Walters, C., Johnsn, G.F. & Caterson, I.D. (1997) Pharmacokinetics of dexamethasone and its relationship to dexamethasone suppression test outcome in depressed patients and healthy control subjects. Biological Psychiatry, 41, 574-584.
29. Panarelli, M., Holloway, C.D., Mulatero, P., Fraser, R. & Kenyon, C.J. (1994) Inhibition of lysozyme synthesis by dexamethasone in human mononuclear leukocytes: an index of glucocorticoid sensitivity. Journal of Clinical Endocrinology and Metabolism, 78, 872-877.
30. Pariante, C.M. & Miller, A.H. (2001) Glucocorticoids in major depression: relevance to pathophysiology and treatment. Biological Psychiatry, 49, 391-404.
31. Pugeat, M.M., Dunn, J.F. & Nisula, B.C. (1981) Transport of steroid hormones: interaction of 70 drugs with testosterone-binding globulin and corticosteroid-binding globulin in human plasma. Journal of Clinical Endocrinology and Metabolism, 53, 69-75.
32. Raivo, T., Palvimo, J.J., Kannisto, S., Voutilainen, R. & Jänne, O.A. (2002) Transactivation assay for determination of glucocorticoid bioactivity in human serum. Journal of Clinical Endocrinology and Metabolism, 87, 3740-3744.
33. Saha, M.T., Laippala, P. & Lenko, H.L. (1997) Growth of asthmatic children is slower during than before treatment with inhaled glucocorticoids. Acta Paediatrica, 86, 138-142.
34. Simeon, D., Guralnik, O., Knutelska, M., Hollander, E. & Schmeidler, J. (2001) Hypothalamic-pituitary-adrenal axis dysregulation in depersonalization disorder. Neuropsychopharmacology, 25, 793-795.
35. Vermeer, H., Hendriks-Stegeman, B.I., Van der Burg, B., Van Buul-Offers, S.C. & Jansen, M. (2003) Glucocorticoid-induced increase in lymphocytic FKBP51 mRNA expression: a potential marker for glucocorticoid sensitivity, potency and bioavailability. Journal of Clinical Endocrinology and Metabolism, 88, 277-284.
36. Whelan, C.J., Payne, A.N. & Planquois, J.-M. (1999) A comparison of the inhibitory effects of budesonide, beclomethasone dipropionate, dexamethasone, hydrocortisone and tixocortol pivalate on cytokine release from leukocytes recovered from human bronchalveolar lavage. Inflammation Research, 48, 224-228.
37. Zhang, X., Moilanen, E. & Kankaanranta, H. (2000) Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide, and beclomethasone. European Journal of Pharmacology, 406, 325-332.